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FBXO17 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. Additionally we are shipping F-Box Protein 17 Antibodies (20) and F-Box Protein 17 Kits (12) and many more products for this protein.
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our studies identify a previously unreported role of FBXO17 in regulating IFN-I signaling
identified FBXO17 as an F-box protein subunit that recognizes and mediates GSK3beta polyubiquitination.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing of this gene results in 2 transcript variants encoding different isoforms.
F-box protein 17
, F-box only protein 17
, F-box only protein 26
, F-box protein FBG4