You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Family with Sequence Similarity 20, Member C (FAM20C) Antibodies

FAM20C encodes a member of the family with sequence similarity 20 (FAM20) family of secreted proteins. Additionally we are shipping FAM20C Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FAM20C 56975 Q8IXL6
FAM20C 80752 Q5MJS3
FAM20C 304334  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-FAM20C Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FAM20C Antibody Titration: 0.2-1 ug/mlPositive Control: NTERA2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-FAM20C Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB DMP4 antibody (C-term) (ABIN654936) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human breast carcinoma  reacted WITH DMP4 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of DMP4 Antibody (C-term) in HepG2 cell line lysates (35ug/lane).This demonstrates the DMP4 antibody detected the DMP4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB FAM20C antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated WB FAM20C antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

FAM20C Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-FAM20C Antibodies

  1. Human Polyclonal FAM20C Primary Antibody for IHC (p), WB - ABIN654936 : Simpson, Scheuerle, Hurst, Patton, Stewart, Crosby: Mutations in FAM20C also identified in non-lethal osteosclerotic bone dysplasia. in Clinical genetics 2009 (PubMed)
    Show all 3 references for ABIN654936

  2. Human Polyclonal FAM20C Primary Antibody for EIA, IHC (p) - ABIN951886 : Simpson, Hsu, Keir, Hao, Sivapalan, Ernst, Zackai, Al-Gazali, Hulskamp, Kingston, Prescott, Ion, Patton, Murday, George, Crosby: Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine syndrome), highlighting a crucial molecule in bone development. in American journal of human genetics 2007 (PubMed)
    Show all 3 references for ABIN951886

More Antibodies against FAM20C Interaction Partners

Human Family with Sequence Similarity 20, Member C (FAM20C) interaction partners

  1. Fam20A (show FAM20A Antibodies) potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro.

  2. The Fam20C-and VLK (show PKDCC Antibodies)-family of kinases mediate the phosphorylation of proteins in the secretory pathway and extracellular space.Mutation in several secretory pathway kinases cause human disease

  3. by treating Fam20C expressing HEK293T cells with myriocin, a potent inhibitor of the sphingosine biosynthetic pathway, the activity of Fam20C released into the conditioned medium is substantially decreased corroborating the concept that sphingosine

  4. Using CRISPR/Cas9 genome editing, mass spectrometry, and biochemistry, study identifies more than 100 secreted phosphoproteins as genuine Fam20C substrates; further, study shows that Fam20C exhibits broader substrate specificity than previously appreciated.

  5. phenotype in two families with non-lethal Raine syndrome with FAM20C mutations

  6. Findings suggest that certain homozygous FAM20C mutations can cause FGF23 (show FGF23 Antibodies)-related hypophosphatemic osteomalacia and indicate the multiple roles of FAM20C in bone.

  7. Results suggest that FAM20C suppresses FGF23 (show FGF23 Antibodies) production by enhancing DMP1 (show DMP1 Antibodies) expression, and inactivating mutations in FAM20C cause FGF23 (show FGF23 Antibodies)-related hypophosphatemia by decreasing transcription of DMP1 (show DMP1 Antibodies).

  8. We report on a child who is homozygous for a 487-kb deletion in 7p22.3 that contains FAM20C

  9. Fam20C phosphorylates FGF23 (show FGF23 Antibodies), which promotes FGF23 (show FGF23 Antibodies) proteolysis by furin (show FURIN Antibodies) by blocking O-glycosylation by polypeptide N-acetylgalactosaminyltransferase 3 (show GALNT3 Antibodies).

  10. mutations in FAM20C provide a putative new mechanism in human subjects leading to dysregulated FGF23 (show FGF23 Antibodies) levels, hypophosphatemia, hyperphosphaturia, dental anomalies, intracerebral calcifications and osteosclerosis of the long bones

Mouse (Murine) Family with Sequence Similarity 20, Member C (FAM20C) interaction partners

  1. Fam20A (show FAM20A Antibodies) potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro.

  2. Loss of Fam20C function leads to periodontal disease in mice

  3. Successful generation of Fam20C-GFP transgenic mice will provide a unique model for studying Fam20C gene expression and the biological function of this gene during odontogenesis and osteogenesis

  4. we have successfully generated the immortalized mouse floxed Fam20c dental papilla mesenchymal and osteoblast cell lines.

  5. These results indicated that the downregulation of Dmp1 (show DMP1 Antibodies) may not directly associate with, or significantly contribute to the bone and dentin defects in the Fam20C-cKO mice.

  6. that FAM20C is not a constituent of the enamel extracellular matrix and functions intracellularly within ameloblasts.

  7. FAM20C is a molecule essential to amelogenesis, its inactivation in the dental epithelium does not significantly affect dentinogenesis.

  8. FAM20C is essential to the differentiation and mineralization of dental tissues through the regulation of molecules critical to the differentiation of tooth-formative cells.

  9. Our findings indicate that FAM20C is essential to the differentiation of osteoblasts/osteocytes and is involved in the regulation of phosphate homeostasis via the mediation of FGF23 (show FGF23 Antibodies)

  10. Fam20c null mice develop hypophosphatemic rickets and defective enamel and dentin

FAM20C Antigen Profile

Protein Summary

This gene encodes a member of the family with sequence similarity 20 (FAM20) family of secreted proteins. A similar gene in mice encodes a protein that plays a role in dentin mineralization, and mutations in the human gene are associated with the autosomal recessive disorder Raine syndrome.

Gene names and symbols associated with FAM20C

  • family with sequence similarity 20, member C (LOC100231802) antibody
  • family with sequence similarity 20, member C (LOC100342945) antibody
  • family with sequence similarity 20, member C (FAM20C) antibody
  • family with sequence similarity 20, member C (Fam20c) antibody
  • family with sequence similarity 20, member C (fam20c) antibody
  • C76981 antibody
  • DMP-4 antibody
  • DMP4 antibody
  • GEF-CK antibody
  • mKIAA4081 antibody
  • RGD1311980 antibody
  • RNS antibody
  • si:ch73-266a4.1 antibody

Protein level used designations for FAM20C

family with sequence similarity 20, member C , dentin matrix protein 4 , extracellular serine/threonine protein kinase FAM20C , golgi-enriched fraction casein kinase , fam20c2

GENE ID SPECIES
100231802 Taeniopygia guttata
100342945 Oryctolagus cuniculus
416445 Gallus gallus
56975 Homo sapiens
491596 Canis lupus familiaris
80752 Mus musculus
304334 Rattus norvegicus
560397 Danio rerio
534672 Bos taurus
Selected quality suppliers for anti-FAM20C (FAM20C) Antibodies
Did you look for something else?