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Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. Additionally we are shipping FAM21C Antibodies (18) and many more products for this protein.
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FAM21 not only functions as an integral component of the cytoplasmic WASH complex, but also modulates NF-kappaB (show NFKB1 Proteins) gene transcription in the nucleus.
Data show that a component of the WASH regulatory complex (SHRC), FAM21, directly interacts with the retromer CSC protein VPS35 (show vps35 Proteins).
WASH exists in a multiprotein complex containing FAM21, which links WASH to endosomes and is required for WASH-dependent retromer-mediated sorting.
a cellular factor, VPEF, is exploited by vaccinia virus for cell entry through fluid phase endocytosis when vaccinia virus enters HeLa cells
Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. In the complex, it probably mediates the recruitment of the complex to endosome membranes (By similarity).
WASH complex subunit FAM21C
, vaccinia virus penetration factor
, WASH complex subunit FAM21