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Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. Additionally we are shipping FAM84A Proteins (6) and many more products for this protein.
Showing 10 out of 32 products:
Chicken Polyclonal FAM84A Primary Antibody for WB - ABIN2785104
Kobayashi, Masaki, Sugiyama, Atomi, Furukawa, Nakamura: A gene encoding a family with sequence similarity 84, member A (FAM84A) enhanced migration of human colon cancer cells. in International journal of oncology 2006
Human Polyclonal FAM84A Primary Antibody for IF (p), IHC (p) - ABIN1386304
Wang, Xu, Qin, Wang, Ma, Luo, Zhang: Myocardin-related transcription factor-A is a key regulator in retinoic acid-induced neural-like differentiation of adult bone marrow-derived mesenchymal stem cells. in Gene 2013
up-regulation of FAM84A may play a critical role in progression of colon cancer
Nse1 RING-like motif is a protein-protein interaction domain required for Smc5 (show SMC5 Antibodies)-Smc6 (show SMC6 Antibodies) holocomplex integrity and recruitment to, or retention at, DNA lesions
FAM84A is up-regulated by CAR during the development of liver tumors.
Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Has in vitro ubiquitin ligase activity in presence of NDNL2. Is involved in positive regulation of response to DNA damage stimulus.
family with sequence similarity 84, member A
, protein FAM84A
, neurologic sensory protein 1
, neurological/sensory 1
, non-structural maintenance of chromosomes element 1 homolog