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anti-Fanconi Anemia Complementation Group I (FANCI) Antibodies

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Additionally we are shipping FANCI Proteins (3) and FANCI Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FANCI 55215 Q9NVI1
Anti-Mouse FANCI FANCI 208836 Q8K368
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Top anti-FANCI Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$859.83
Details
Human Rabbit Un-conjugated IF, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of FANCI expression in transfected 293T cell line by FANCI MaxPab polyclonal antibody.Lane 1: FANCI transfected lysate(8.14 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF, WB   100 μL Log in to see 11 to 16 Days
$675.71
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$240.90
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$240.90
Details
Human Rabbit Un-conjugated IP, WB   20 μg Log in to see 8 to 10 Days
$815.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$859.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details

FANCI Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,
,

More Antibodies against FANCI Interaction Partners

Human Fanconi Anemia Complementation Group I (FANCI) interaction partners

  1. FANCI mutations are associated with Fanconi anemia (show PALB2 Antibodies) in VACTERL association.

  2. FANCJ (show BRIP1 Antibodies) protein is important for the stability of FANCD2 (show FANCD2 Antibodies)/FANCI proteins and protects them from proteasome and caspase-3 (show CASP3 Antibodies) dependent degradation.

  3. These findings indicate that FANCI functions upstream of FA core complex recruitment independently of FANCD2 (show FANCD2 Antibodies), and alter the current view of the FA-BRCA pathway.

  4. these purification methods for human FANCI and FANCD2 (show FANCD2 Antibodies) provide novel procedures to facilitate structural and biochemical studies of human FANCI and FANCD2 (show FANCD2 Antibodies).

  5. Results show that ATR (show ANTXR1 Antibodies)-mediated phosphorylation of FANCI, controls dormant origin firing in response to DNA replication stress.

  6. Our studies reveal a previously unknown mechanism for the coordinate nuclear import of a subset of FANCD2 and FANCI, a key early step in the cellular ICL response.

  7. Mutations in FANCI that impair its DNA binding activity compromise DNA-stimulated FANCD2 (show FANCD2 Antibodies) monoubiquitination.

  8. A CUE ubiquitin-binding domain in the FANCD2 (show FANCD2 Antibodies) protein is required for interaction with FANCI, retention of monoubiquitinated FANCD2 (show FANCD2 Antibodies), and FANCI in chromatin, and for efficient DNA interstrand crosslinks repair.

  9. These data suggest a key role for the E3 ligase activity of RAD18 (show RAD18 Antibodies) in the recruitment of FANCD2 (show FANCD2 Antibodies) and FANCI to chromatin and the events leading to their ubiquitylation during S phase.

  10. although proper nuclear localization of FANCI is crucial for robust FANCD2 (show FANCD2 Antibodies) monoubiquitination, the putative FANCI EDGE motif is important for DNA crosslink repair

Mouse (Murine) Fanconi Anemia Complementation Group I (FANCI) interaction partners

  1. crystal structure of FANCI-FANCD2 (show FANCD2 Antibodies)(ID) complex; crystallographic electron-density map of FANCI protein bound to splayed Y DNA; data suggest ID complex recognizes DNA structures resulting from encounter of replication forks with an interstrand cross-link

FANCI Antigen Profile

Protein Summary

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Gene names and symbols associated with FANCI

  • Fanconi anemia, complementation group I (FANCI) antibody
  • Fanconi anemia, complementation group I (Fanci) antibody
  • KIAA1794 antibody

Protein level used designations for FANCI

Fanconi anemia group I protein , Fanconi anemia group I protein homolog

GENE ID SPECIES
55215 Homo sapiens
208836 Mus musculus
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