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anti-Fat Mass and Obesity-Associated (FTO) Antibodies

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Additionally we are shipping Fat Mass and Obesity-Associated Proteins (11) and Fat Mass and Obesity-Associated Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top anti-Fat Mass and Obesity-Associated Antibodies at antibodies-online.com

Showing 10 out of 125 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of FTO Antibody (N-term) in NCI-H460 cell line l... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Mouse Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$445.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN308414 (0.03µg/ml) staining of Human Pancreas lysate (35µg protein... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of FTO Antibody (N-term) (ABIN390964) in NCI-H46... Formalin-fixed and paraffin-embedded human brain tissue reacted with F... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of FTO in mouse brain tissue with FTO antibody at... Western blot analysis of FTO in human uterus tissue lysate with AP3035... 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-FTO Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62... WB Suggested Anti-FTO  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Fto Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:15... WB Suggested Anti-Fto  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC, WB 100 μL Log in to see 2 to 3 Days
$283.50
Details
Mouse Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details

FTO Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Mouse (Murine) , , , ,
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Rat (Rattus) , , , ,
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Top referenced anti-Fat Mass and Obesity-Associated Antibodies

  1. Human Polyclonal FTO Primary Antibody for EIA, WB - ABIN453035 : Scott, Mohlke, Bonnycastle, Willer, Li, Duren, Erdos, Stringham, Chines, Jackson, Prokunina-Olsson, Ding, Swift, Narisu, Hu, Pruim, Xiao, Li, Conneely, Riebow, Sprau, Tong, White, Hetrick, Barnhart, Bark, Goldstein, Watkins, Xiang, Saramies, Buchanan, Wat: A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. in Science (New York, N.Y.) 2007 (PubMed)

  2. Human Polyclonal FTO Primary Antibody for EIA, IHC (p) - ABIN499863 : Scuteri, Sanna, Chen, Uda, Albai, Strait, Najjar, Nagaraja, Orrú, Usala, Dei, Lai, Maschio, Busonero, Mulas, Ehret, Fink, Weder, Cooper, Galan, Chakravarti, Schlessinger, Cao, Lakatta, Abecasis: Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. in PLoS genetics 2008 (PubMed)

  3. Human Polyclonal FTO Primary Antibody for ELISA, WB - ABIN308414 : Gerken, Girard, Tung, Webby, Saudek, Hewitson, Yeo, McDonough, Cunliffe, McNeill, Galvanovskis, Rorsman, Robins, Prieur, Coll, Ma, Jovanovic, Farooqi, Sedgwick, Barroso, Lindahl, Ponting, Ashcroft et al.: The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ... in Science (New York, N.Y.) 2007 (PubMed)

  4. Cow (Bovine) Monoclonal FTO Primary Antibody for IF, IHC (p) - ABIN782440 : Fredriksson, Hägglund, Olszewski, Stephansson, Jacobsson, Olszewska, Levine, Lindblom, Schiöth: The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. in Endocrinology 2008 (PubMed)

More Antibodies against Fat Mass and Obesity-Associated Interaction Partners

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. data showed that the rs9939609 FTO gene polymorphism is not a useful genetic test prior to laparoscopic sleeve gastrectomy to help clinicians predicting the weight loss for severely obese patients in short-term follow-up.

  2. The A-allele frequencies (95% CI) of FTO polymorphisms rs8050136 and rs9939609 were 39% (34-44%); 38% (33-43%) and 40% (35-45%); 41% (36-46%), respectively.

  3. The effects of exercise combined with dietary intervention on obesity were associated with the FTO rs9939609 polymorphism in Chinese adolescents and children.

  4. Individuals carrying the homozygous FTO obesity-predisposing allele may lose more weight through diet/lifestyle interventions than noncarriers. [Review, Meta-analysis]

  5. data suggest that FTO SNPs make differential contributions to obesity risk and support the hypothesis that gender differences in the mechanisms involving these variants may contribute to disease development

  6. There is a different evolution of weight loss in obese carriers of the FTO gene variant rs9939609 after bariatric surgery...evident at only 2 y postbariatric surgery, inducing a lower proportion of surgery success and a greater and earlier weight regain.

  7. The young Polish population is characterized by two disparate haplotypes of common FTO gene variants: TCGA (a risk SNP haplotype), and CTAT (a protective haplotype) in terms of body fat distribution.

  8. FTO rs9939609 associated with aortic valve stenosis in German men. Heterozygotes had a significantly lower chance to develop AVS. This was independent of BMI and other variables such as diabetes mellitus.

  9. Presurgery vitamin D levels influence the size of genotype effects of FTO rs9939609 on RYGB surgery-induced weight loss in obese patients.

  10. PPARgamma2 (show PPARG Antibodies) (rs1801282) and FTO (rs9939609) are associated with T2D susceptibility.

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. FTO-dependent N6-methyladenosine demethylation may be affected by betaine.

  2. FTO modulates circadian rhythms and inhibits the CLOCK-BMAL1 (show ARNTL Antibodies)-induced transcription.

  3. FTO expression and N6-methyladenosine levels are inversely correlated during adipogenesis. FTO depletion blocks differentiation and only catalytically active FTO restores adipogenesis.

  4. FTO is present in both the nucleus and cytoplasm, with a mobile fraction that shuttles between both cellular compartments, possibly by interaction with XPO2 (show CSE1L Antibodies).

  5. FTO plays an important role in the development of metabolic disorders and is an interesting target for therapeutic agents.

  6. data suggest that IRX3 (show IRX3 Antibodies) is a functional long-range target of obesity-associated variants within FTO and represents a novel determinant of body mass and composition

  7. FTO silencing did not modify PPARgamma2 (show PPARG Antibodies) mRNA levels. Partial reduction of FTO did not influence the first step of 3T3-L1 adipocyte differentiation.

  8. Downregulation was seen only with essential amino-acid deficiency and not with non-essential amino acids. These data suggest that FTO might have a role in the sensing of essential amino-acid availability.

  9. Data suggest that Fto-deficient white adipocytes exhibit some metabolic functions similar to brown adipocytes; expression of Ucp1 (uncoupling protein-1 (show UCP1 Antibodies)) is up-regulated and mitochondrial uncoupling is increased in Fto-deficient adipocytes.

  10. Inactivation of the Fto gene impairs dopamine receptor types 2 & 3 control of neuronal activity & behavioral responses. FTO regulates the demethylation of specific mRNAs in vivo, and this activity relates to the control of DA transmission.

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (show CSN2 Antibodies) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

Fat Mass and Obesity-Associated (FTO) Antigen Profile

Protein Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • fat mass and obesity associated (FTO) antibody
  • fat mass and obesity associated (Fto) antibody
  • fat mass and obesity associated (fto) antibody
  • AW743446 antibody
  • mKIAA1752 antibody
  • RGD1305121 antibody

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

GENE ID SPECIES
79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
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