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FCGR2C encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. Additionally we are shipping FCGR2C Antibodies (48) and FCGR2C Proteins (2) and many more products for this protein.
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Gene copy number variation (CNV) of the PKLR (show PKLR ELISA Kits), FCGR2A (show FCGR2A ELISA Kits), FCGR2C, and FCGR3 (show CD16 ELISA Kits) genes is associated with malaria severity, and our results provide evidence for a role of CNV in host responses to malaria.
FCGR2A (show FCGR2A ELISA Kits) and FCGR2C polymorphisms may also contribute to immunocomplexemia present in sarcoidosis.
FCGR2C SNPs that associated with vaccine efficacy in RV144 also strongly associated with the expression of FCGR2A (show FCGR2A ELISA Kits)/C and one of them also associated with the expression of Fc receptor-like A (FCRLA (show FCRLA ELISA Kits)), another Fc-gamma receptor (show FCGR1A ELISA Kits) (FcgammaR) gene
These include an FCGR2A (show FCGR2A ELISA Kits)/2C chimeric gene that causes a decreased expression
Data show that gains or losses in copy numbers of Fc gamma receptors FCGR3A (show CD16 ELISA Kits) were less frequent than for FCGR3B (show CD16 ELISA Kits) and FCGR2C.
Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus.(28-40) Status: Complete Incomplete Delete
Only FCGR3A, FCGR2C and FCGR3B show copy number variation, in contrast to FCGR2A and FCGR2B.
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants.
Fc gamma receptor IIC
, IgG Fc receptor II-c
, immunoglobulin G Fc receptor II-c
, low affinity immunoglobulin gamma Fc region receptor II-c