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Fc Receptor-Like 3 Proteins (FCRL3)

FCRL3 encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. Additionally we are shipping Fc Receptor-Like 3 Antibodies (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat FCRL3 FCRL3 680697  
FCRL3 115352 Q96P31
Mouse FCRL3 FCRL3 329693 Q68SN8
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Top Fc Receptor-Like 3 Proteins at

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Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 59 to 64 Days

FCRL3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Fc Receptor-Like 3 (FCRL3) Interaction Partners

Human Fc Receptor-Like 3 (FCRL3) interaction partners

  1. CTLA4 (show CTLA4 Proteins) and FCRL3 genes overexpression may play an important role in children suffering from autoimmune thyroiditis.

  2. FCRL3 genetic polymorphisms were associated with an increased risk of endometriosis-related infertility, regardless of symptoms.

  3. 4 Single Nucleotide Polymorphisms (rs7528684, rs945635, rs3761959, and rs2282284) could significantly elevate the risk of Neuromyelitis Optica in Chinese Han population.

  4. study found a significant association between the SNPs in FCRL3 gene and allergic rhinitis (AR) in Chinese Han patients; results suggest these gene polymorphisms might be the autoimmunity risk for AR

  5. Association between FCRL3 polymorphisms and increased risk of sudden sensorineural hearing loss in a Chinese Han population.

  6. the TIGIT (show TIGIT Proteins)/FCRL3 combination allows reliable identification of Helios (show ZNFN1A2 Proteins)(+) Treg cells even in highly activated conditions in vitro as well as in PBMCs of autoimmune patients.

  7. CONCLUSIONS: Our study demonstrated that the FCRL3 -169T>C polymorphism is not a risk factor of systemic lupus erythematosus in the Polish population, but this polymorphism may contribute to autoantibody production in this disease.

  8. the FCRL3 polymorphisms are associated with not only autoimmune diseases including RA, GD, T1D, and other disease under different genetic models, but also different ethnic subgroups.

  9. meta-analysis of published studies including 2,544 patients and 3,913 controls demonstrates that the FCRL3 -169 C/T polymorphism does not confer susceptibility to systemic lupus erythematosus in Europeans or Asians

  10. FCRL3 -169T>C polymorphism alters the expression of FCRL3 and can be a risk factor of endometriosis-related infertility.

Mouse (Murine) Fc Receptor-Like 3 (FCRL3) interaction partners

  1. FCRL5 (show FCRL5 Proteins) exerts binary and compartment-specific influence on innate-like B-cell receptor signaling.

  2. The three amino-terminal immunoglobulin domains of FCRL5 (show FCRL5 Proteins) are required for binding of orthopoxvirus histocompatibility class I-like protein to B (show TDO2 Proteins) cells and monocytes/macrophages.

  3. Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment.

Fc Receptor-Like 3 (FCRL3) Protein Profile

Protein Summary

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.

Gene names and symbols associated with Fc Receptor-Like 3 Proteins (FCRL3)

  • Fc receptor-like 3 (FCRL3)
  • Fc receptor-like 3 (Fcrl3)
  • Fc receptor-like 3 (fcrl3-a)
  • Fc receptor-like 3 (fcrl3)
  • Fc receptor-like 3 (fcrl3-b)
  • Fc receptor-like 5 (Fcrl5)
  • CD307c protein
  • Fcrh3 protein
  • IFGP3 protein
  • IRTA3 protein
  • mBXMH2 protein
  • SPAP2 protein
  • xfl1.2 protein

Protein level used designations for Fc Receptor-Like 3 Proteins (FCRL3)

Fc receptor-like 3 , type I TM-receptor XFL1.2a , type I TM-receptor XFL1.2b , Fc receptor-like protein 3-like , Fc receptor homolog 3 , Fc receptor-like protein 3 , IFGP family protein 3 , SH2 domain-containing phosphatase anchor protein 2 , fcR-like protein 3 , hIFGP3 , immune receptor translocation-associated protein 3 , immunoglobulin superfamily receptor translocation associated protein 3 , BXMAS1-like protein 2 , Fc receptor-like protein 5 , fc receptor homolog 3 , fcR-like protein 5 , moFcRH3

469519 Pan troglodytes
515085 Bos taurus
680697 Rattus norvegicus
718801 Macaca mulatta
733242 Xenopus laevis
734130 Xenopus (Silurana) tropicalis
779034 Xenopus laevis
100444413 Pongo abelii
100464205 Ailuropoda melanoleuca
100594898 Nomascus leucogenys
115352 Homo sapiens
329693 Mus musculus
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