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This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. Additionally we are shipping FOXE1 Proteins (3) and many more products for this protein.
Showing 10 out of 57 products:
Human Polyclonal FOXE1 Primary Antibody for IHC, ELISA - ABIN185032
Clifton-Bligh, Wentworth, Heinz, Crisp, John, Lazarus, Ludgate, Chatterjee: Mutation of the gene encoding human TTF-2 associated with thyroid agenesis, cleft palate and choanal atresia. in Nature genetics 1998
Cow (Bovine) Polyclonal FOXE1 Primary Antibody for WB - ABIN2777423
Carré, Castanet, Sura-Trueba, Szinnai, Van Vliet, Trochet, Amiel, Léger, Czernichow, Scotet, Polak: Polymorphic length of FOXE1 alanine stretch: evidence for genetic susceptibility to thyroid dysgenesis. in Human genetics 2008
Human Polyclonal FOXE1 Primary Antibody for EIA, IHC (p) - ABIN452689
Zhang, Zuo, Nakamura, Nakamura, Wakasa, Kakudo: Immunohistochemical analysis of thyroid-specific transcription factors in thyroid tumors. in Pathology international 2006
These results indicate that Foxe1 overexpression is not directly involved in the development of thyroid cancer and that proper Foxe1 dosage is essential for achieving normal structure and function of the thyroid.
Foxe1 mRNA expression was suppressed in HR-overexpressing skin, as well as in HR-expressing keratinocytes.
MSX1 (show MSX1 Antibodies) and TGF-beta3 (show TGFB3 Antibodies) are direct targets of FOXE1.
Data report a detailed expression pattern of thyroid transcription factor-2 protein during mouse embryogenesis.
Foxe1 is required for hair follicle morphogenesis.
In the analysis of all OFCs combined, SNPs near FOXE1 reached genome-wide significance
We confirmed associations with papillary thyroid cancer and SNPs in FOXE1/HEMGN, SERPINA5 (show SERPINA5 Antibodies) (rs2069974), FTO (show FTO Antibodies) (rs8047395), EVPL (show EVPL Antibodies) (rs2071194), TICAM1 (show TICAM1 Antibodies) (rs8120) and SCARB1 (show SCARB1 Antibodies) (rs11057820) genes. We found associations with SNPs in FOXE1, SERPINA5 (show SERPINA5 Antibodies), FTO (show FTO Antibodies), TICAM1 (show TICAM1 Antibodies) and HSPA6 (show HSPA6 Antibodies) and and follicular thyroid cancer
FOXE1 was the only gene which was over-expressed in six out of eight lung cancer cell lines and human cancer tissue specimens and is an important regulator by targeting autophagy and Matrix Metalloproteinases pathways in lung cancer development.
Taken together, this study showed that rs7043516 may be considered as a potentially susceptible marker of cleft lip only among Chinese Han populations.
this study shows that FOXE1 polymorphism is strongly associated with non-syndromic cleft lip and palate in populations in northeast China
High Levels of mRNA of both FOXE1 are associated with benign than in malignant thyroid lesions.
Our findings suggest that FOXE1 variations generate a higher risk for poor histopathological features of papillary thyroid carcinoma
analysis of novel somatic mutations of FOXE1 in papillary thyroid cancer
Causal mutations for orofacial clefting and thyroid diseases occur within cis (show CISH Antibodies)-regulatory elements at the human FOXE1 locus.
In pancreatic cancer cells, AF6 (show MLLT4 Antibodies) is expressed at reduced levels, causing Dvl2 (show DVL2 Antibodies) to be upregulated and available to bind and enhance FOXE1-induced trans-activation of Snail (show SNAI1 Antibodies), which promotes proliferation and metastasis.
Xenopus FoxE1, a gene that is primarily expressed in the developing pituitary and thyroid
This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. This gene functions as a thyroid transcription factor which likely plays a crucial role in thyroid morphogenesis. Mutations in this gene are associated with congenital hypothyroidism and cleft palate with thyroid dysgenesis. The map localization of this gene suggests it may also be a candidate gene for squamous cell epithelioma and hereditary sensory neuropathy type I.
forkhead box E1 (thyroid transcription factor 2)
, forkhead box E1
, forkhead box E protein
, thyroid transcription factor 2
, forkhead box protein E1
, HNF-3/fork head-like protein 5
, forkhead box E2
, forkhead box protein E2
, forkhead, drosophila, homolog-like 15
, forkhead-related protein FKHL15