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FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. Additionally we are shipping FOXQ1 Antibodies (86) and FOXQ1 Kits (1) and many more products for this protein.
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Data suggest that forkhead box Q1 (FOXQ1) is a potential therapeutic target for the development of therapies for colorectal cancer.
we identified FOXQ1 as an oncogene (show RAB1A Proteins) to promote ESCC tumor cell proliferation and metastasis by negatively regulating CDH1 (show CDH1 Proteins) in esophageal squamous cell carcinoma cells
MiR (show MLXIP Proteins)-1271 inhibits cell proliferation, invasion, and epithelial-mesenchymal transition in gastric cancer by directly suppressing FOXQ1 expression.
Results demonstrate that miR (show MLXIP Proteins)-124 functions as a tumor-suppressive microRNA in nasopharyngeal carcinoma by repressing Foxq1 expression.
FoxQ1 expression is negatively associated with the overall survival of PC patients, and that this protein may therefore represent a novel molecular target and new prognostic biomarker for PC.
miR (show MLXIP Proteins)-506 functions as a tumor suppressor miRNA in nasopharyngeal carcinoma; its suppressive effects are mediated chiefly by repressing FOXQ1 expression.
NSCLC cells with silenced FoxQ1 had decreased cell proliferation, migration and invasion in cell culture and delayed growth of xenograft tumors in mice compared with corresponding control cells.
PDGFRalpha and beta can be directly regulated by Foxq1 or indirectly regulated through the Foxq1/Twist1 (show TWIST1 Proteins) axis
The induction of EMT (show ITK Proteins) by FOXQ1 defines a new transfer function in promoting cancer behind possible mechanisms.
FOXQ1 expression is essential to maintain cell proliferation, motility/invasion, and epithelial-mesenchymal transition phenotypes in ovarian cancer cells.
R164C mutation in FOXQ1 H3 domain affects formation of the hair medulla in mice.
This study has elucidated the functional impact of FoxQ1 on epithelial differentiation.
satin hair mutant gene Foxq1 is among multiple and functionally diverse regulatory targets for Hoxc13 during hair follicle differentiation
Ultrastructural analysis suggests that the gastric acid secretion defect in Foxq1-deficient mice might be due to impairment in the fusion of cytoplasmic tubulovesicles to the apical membrane of secretory canaliculi.
Transcription factor foxq1 controls MUC5AC gene expression and granule content in mouse stomach surface mucous cells.
FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001
forkhead box Q1
, forkhead transcription factor Q1
, fork-head box Q1 transcription factor
, HNF-3/forkhead-like protein 1
, forkhead box protein Q1
, hepatocyte nuclear factor 3 forkhead homolog 1
, winged helix/forkhead transcription factor
, HNF-3/forkhead homolog 1 like
, HNF-3/forkhead homolog-1