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Fragile X Mental Retardation, Autosomal Homolog 2 Proteins (FXR2)

The protein encoded by FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. Additionally we are shipping Fragile X Mental Retardation, Autosomal Homolog 2 Antibodies (55) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FXR2 9513 P51116
FXR2 23879  
Rat FXR2 FXR2 287433  
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Top Fragile X Mental Retardation, Autosomal Homolog 2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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FXR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2) Interaction Partners

Human Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2) interaction partners

  1. An accumulation of 8 SNPs in the fragile gene family (FMR1 (show FMR1 Proteins), FXR1 (show FXR1 Proteins) and FXR2)were found associated with autistic traits in a sample of male patients.

  2. Data show that the nuclear localization signals of the FXR1 (show FXR1 Proteins) and FXR2 comprise tandem Tudor domain architectures.

  3. These results indicate that FMR1 (show FMR1 Proteins) gene function is evolutionarily conserved in neural mechanisms and cannot be compensated by either FXR1 (show FXR1 Proteins) or FXR2, but that all three proteins can substitute for each other in non-neuronal requirements.

  4. FXR1P (show FXR1 Proteins) and FXR2P KH2 (show KCNG1 Proteins) domains bind G-quadruplex and kissing complex RNA with the same affinity as the FMRP (show FMR1 Proteins) KH2 (show KCNG1 Proteins) domain.

Mouse (Murine) Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2) interaction partners

  1. Both Fmr1 (show FMR1 Proteins) and Fxr2 knockout mice have reduced fat deposits and glucose metabolism.

  2. these findings show a coordinated regulation of PSD95/Dlg4 (show DLG4 Proteins) mRNA by FMRP (show FMR1 Proteins) and FXR2P that ultimately affects its fine-tuning during synaptic activity.

  3. Differential regulation of SVZ and DG stem cells by FXR2 may be a key component of the mechanism that governs the different neurogenic processes in these two adult germinal.

  4. Findings suggest that Fmr1 (show FMR1 Proteins) and Fxr2 genes contribute in a cooperative manner to pathways controlling locomotor activity, sensorimotor gating and cognitive processes.

  5. Fxr2 regulates mammalian circadian behavioral rhythms.

  6. to unravel the function of Fxr2 protein, the expression pattern of 12,588 genes was studied in the brains of wild-type and Fxr2 knockout mice; genes and gene groups de-regulated in the brains of Fxr2 knockout mice were identified

  7. FXR1P (show FXR1 Proteins) and FXR2P KH2 (show KCNG1 Proteins) domains bind G-quadruplex and kissing complex RNA with the same affinity as the FMRP (show FMR1 Proteins) KH2 (show KCNG1 Proteins) domain.

Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2) Protein Profile

Protein Summary

The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.

Gene names and symbols associated with FXR2

  • fragile X mental retardation, autosomal homolog 2 (FXR2)
  • fragile X mental retardation, autosomal homolog 2 (fxr2)
  • fragile X mental retardation, autosomal homolog 2 (Fxr2)
  • FMR1L2 protein
  • Fxr2h protein
  • FXR2P protein
  • id:ibd5046 protein
  • zgc:56215 protein
  • zgc:77472 protein

Protein level used designations for FXR2

fragile X mental retardation syndrome-related protein 2 , fragile X mental retardation syndrome related protein 2 , fragile X mental retardation, autosomal homolog 2 , fragile X mental retardation syndrome-related protein 2-like , fragile X-mental retardation 1-like 2 , fragile X mental retardation gene 2, autosomal homolog , fragile X mental retardation-related protein 2

GENE ID SPECIES
100512131 Sus scrofa
393180 Danio rerio
721889 Macaca mulatta
749002 Pan troglodytes
100343838 Oryctolagus cuniculus
100387469 Callithrix jacchus
9513 Homo sapiens
23879 Mus musculus
489478 Canis lupus familiaris
618127 Bos taurus
287433 Rattus norvegicus
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