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anti-G Protein-Coupled Receptor 4 (GPR4) Antibodies

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.. Additionally we are shipping GPR4 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GPR4 2828 P46093
GPR4 319197 Q8BUD0
GPR4 308408 Q4KLH9
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Top anti-GPR4 Antibodies at antibodies-online.com

Showing 10 out of 32 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB GPR4 Antibody (Center) (ABIN1881386) western blot analysis in WiDr cell line and rat liver tissue lysates (35 µg/lane). This demonstrates the GPR4 antibody detected the GPR4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-GPR4 antibody  ABIN1048816 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-GPR4 antibody  ABIN1048818 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ICC, IHC (p) Anti-GPR4 antibody  ABIN1048817 IHC staining of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated ICC, IHC (p) 50 μg Log in to see 11 to 13 Days
$541.80
Details

GPR4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,


Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-GPR4 Antibodies

  1. Human Polyclonal GPR4 Primary Antibody for WB - ABIN1881386 : Heiber, Docherty, Shah, Nguyen, Cheng, Heng, Marchese, Tsui, Shi, George: Isolation of three novel human genes encoding G protein-coupled receptors. in DNA and cell biology 1995 (PubMed)
    Show all 4 references for ABIN1881386

More Antibodies against GPR4 Interaction Partners

Human G Protein-Coupled Receptor 4 (GPR4) interaction partners

  1. GPR4 induces angiogenesis via GPR4-induced p38 (show CRK Antibodies)-mediated IL6 (show IL6 Antibodies), IL8 (show IL8 Antibodies) and VEGFA (show VEGFA Antibodies) secretion at acidic extracellular pH in squamous cell carcinoma of the head and neck

  2. The results suggested that GPR4 may play an important role in the development of epithelial ovarian carcinoma (EOC), and its overexpression might be required for the angiogenesis, tumor growth, and metastasis of EOC

  3. acidosis/GPR4 signaling regulates endothelial cell adhesion mainly through the G(s)/cAMP/Epac (show RAPGEF3 Antibodies) pathway

  4. The mutation of histidine residue at 79, 165, or 269 from the N-terminal of GPR4 to phenylalanine shifted the half-maximal effective concentration (EC(50)) of proton-induced signaling activities to the right, including cAMP accumulation.

  5. Endogenous GPR4 in endothelial cells may be a potential G protein-coupled receptor (show ADRA1A Antibodies) by which LPC (show PCSK7 Antibodies) signals proinflammatory activities.

  6. GPR4, a close relative of OGR1 (show GPR68 Antibodies), also responds to pH changes, but elicits cyclic AMP (show APRT Antibodies) formation

  7. sphingosylphosphorylcholine and lysophosphatidic acid are not the ligands for GPR4 and that this receptor may constitutively inhibit ERK1/2 (show MAPK1/3 Antibodies) activation

  8. GPR4 and TDAG8 (show GPR65 Antibodies) overexpression in human tumors plays a role in driving or maintaining tumor formation

  9. results identify sphingosylphosphorylcholine and its receptor, G protein-coupled receptor 4(GPR4), as critical regulators of the angiogenic potential of endothelial cells

  10. GPR4 may play a critical role in the inflammatory responses activated by lysophosphatidylcholine

Mouse (Murine) G Protein-Coupled Receptor 4 (GPR4) interaction partners

  1. knockdown of a proton-sensing G protein-coupled receptor (show GPR34 Antibodies) GPR4 markedly reduced CHOP (show DDIT3 Antibodies) expression and endothelial cell apoptosis after hypoxia exposure.

  2. The results indicate that through the G12 (show TCF3 Antibodies)/13/Rho signaling pathway GPR4 modulates focal adhesion dynamics and reduces cell spreading and membrane ruffling.

  3. The data identify GPR4 and TASK-2 (show KCNK5 Antibodies) as distinct, parallel, and essential central mediators of respiratory chemosensitivity.

  4. These results suggested that, at least in part, RANKL (show TNFSF11 Antibodies) expression by osteoblasts in an acidic environment was mediated by cAMP/PKA signaling resulting from GPR4 activation.

  5. GPR4 modulates glucose homeostasis by increasing insulin (show INS Antibodies) sensitivity.

  6. Reduced pathological angiogenesis and tumor growth in mice lacking GPR4, a proton sensing receptor.

  7. findings suggest that GPR4 activation by an acidic pH inhibits tumor cell migration and invasion, and the Rho GTPase (show RACGAP1 Antibodies) is at least partly responsible for this phenotype

  8. These results suggest that GPR4 deficiency leads to partially penetrant vascular abnormalities during development and that this receptor functions in blood vessel pH sensing.

GPR4 Antigen Profile

Protein Summary

Proton-sensing receptor coupled to several G-proteins, including G(s), G(13) and G(q)/G(11) proteins, leading to cAMP production.

Gene names and symbols associated with GPR4

  • G protein-coupled receptor 4 (GPR4) antibody
  • G protein-coupled receptor 4 (Gpr4) antibody

Protein level used designations for GPR4

G-protein coupled receptor 19 , G-protein coupled receptor 4

GENE ID SPECIES
2828 Homo sapiens
319197 Mus musculus
308408 Rattus norvegicus
512876 Bos taurus
100144489 Sus scrofa
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