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GATA1 encodes a protein which belongs to the GATA family of transcription factors. Additionally we are shipping GATA1 Kits (11) and GATA1 Proteins (9) and many more products for this protein.
Showing 10 out of 235 products:
Human Polyclonal GATA1 Primary Antibody for IF, IHC (p) - ABIN197168
Trainor, Evans, Felsenfeld, Boguski: Structure and evolution of a human erythroid transcription factor. in Nature 1990
Show all 5 references for ABIN197168
Human Polyclonal GATA1 Primary Antibody for IF, IHC (p) - ABIN196684
Nichols, Crispino, Poncz, White, Orkin, Maris, Weiss: Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1. in Nature genetics 2000
Show all 3 references for ABIN196684
Human Polyclonal GATA1 Primary Antibody for IF, IHC - ABIN1532881
Freson, Devriendt, Matthijs, Van Hoof, De Vos, Thys, Minner, Hoylaerts, Vermylen, Van Geet: Platelet characteristics in patients with X-linked macrothrombocytopenia because of a novel GATA1 mutation. in Blood 2001
Show all 3 references for ABIN1532881
Human Monoclonal GATA1 Primary Antibody for ICC, IHC - ABIN969166
Blackford, Parmigiani, Kensler, Wolfgang, Jones, Zhang, Parsons, Lin, Leary, Eshleman, Goggins, Jaffee, Iacobuzio-Donahue, Maitra, Klein, Cameron, Olino, Schulick, Winter, Vogelstein, Velculescu, Kinzler, Hruban: Genetic mutations associated with cigarette smoking in pancreatic cancer. in Cancer research 2009
Show all 3 references for ABIN969166
Human Polyclonal GATA1 Primary Antibody for IF, WB - ABIN196686
Kadri, Maouche-Chretien, Rooke, Orkin, Romeo, Mayeux, Leboulch, Chretien: Phosphatidylinositol 3-kinase/Akt induced by erythropoietin renders the erythroid differentiation factor GATA-1 competent for TIMP-1 gene transactivation. in Molecular and cellular biology 2005
Human Polyclonal GATA1 Primary Antibody for WB - ABIN374593
Li, Godinho, Klusmann, Garriga-Canut, Yu, Orkin: Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. in Nature genetics 2005
Cow (Bovine) Polyclonal GATA1 Primary Antibody for WB - ABIN2792607
de Vooght, van Wijk, van Solinge: GATA-1 binding sites in exon 1 direct erythroid-specific transcription of PPOX. in Gene 2008
deletion of P-sel disrupted megakaryocyte/neutrophil interactions in spleen, reduced TGF-beta (show TGFB1 Antibodies) content, and corrected the hematopoietic stem cells distribution that in Gata1(low) mice, as in primary myelofibrosis patients, is abnormally expanded in spleen.
findings suggest that Gata1 & PU.1 transcription factors are only executing and reinforcing lineage choice once made. These results challenge the current prevailing model of early myeloid lineage choice
GATA1 and PU.1 bind in vitro and in vivo the proximal promoter region of the RPS19 (show RPS19 Antibodies) gene which is frequently mutated in Diamond-Blackfan Anemia.
TAL1 (show TAL1 Antibodies) and GATA1 form a precisely organized complex at a compound motif consisting of a TG 7 or 8 bp upstream of a WGATAA motif across thousands of genomic locations
We propose that the CID (show CENPA Antibodies)-dependent dimerization system combined with the EpoR (show EPOR Antibodies) intracellular domain and the Gata1 gene regulatory region generates a novel peroral strategy for the treatment of anemia.
immunoprecipitation. Our data provide new insights into the expanded regulatory circuitry that coordinates Nanog expression.
Scrib (show SCRIB Antibodies) is a novel proinflammatory regulator in endothelial cells, which maintains the protein expression of GATA-like protein-1 (show ZGLP1 Antibodies).
Inducible Gata1 suppression expands megakaryocyte-erythroid progenitors from embryonic stem cells
By ablating TAF10 (show TAF10 Antibodies) specifically in erythroid cells in vivo, observed is a differentiation block accompanied by deregulated GATA1 target genes, including Gata1 itself, suggesting functional cross talk between GATA1 and TAF10 (show TAF10 Antibodies).
GATA-1 deficiency can partially rescue the trabecular bone loss observed with osteoprotegerin (show TNFRSF11B Antibodies) deficiency
trisomy 21 perturbed hematopoietic development through the enhanced production of early hematopoietic progenitors and the upregulation of mutated GATA1, resulting in the accelerated production of aberrantly differentiated cells.
Data show that pyruvate kinase (PK) activity was decreased in the GATA1 hemizygous state and PKLR (show PKLR Antibodies) c.1284delA variant.
GATA1 mutations were identified in consecutive Down syndrome patients with transient myeloproliferative disorder or acute leukemia.
expression of GATA1 and SET7 (show SETD7 Antibodies) was upregulated and positively correlated with VEGF (show VEGFA Antibodies) expression and microvessel number in 80 breast cancer patients. GATA1 and SET7 (show SETD7 Antibodies) are independent poor prognostic factors in breast cancer.
Molecular cytogenetic analysis of leukemic blast cells indicated that increased blast cell status was caused by transient abnormal myelopoiesis with trisomy 21 and GATA1 mutation.
study provides insight into GATA1 transcriptional activity and may prove a useful resource for investigating the pathogenicity of noncoding variants in human erythroid disorders.
Concurrent exogenous expression of three transcription factors, GATA1, FLI1 (show FLI1 Antibodies) and TAL1 (show TAL1 Antibodies), enables large-scale production of megakaryocytes from human pluripotent stem cells.
The GATA-1-mediated inhibition of PU.1 gene transcription in human AML-erythroleukemias mediated through the URE represents important mechanism that contributes to PU.1 downregulation and leukemogenesis that is sensitive to DNA demethylation therapy
findings provide insights into the clinically relevant in vivo function of the N-terminal domain of GATA1 in human hematopoiesis.
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.
GATA binding protein 1 (globin transcription factor 1)
, aspartyl/glutamyl-tRNA amidotransferase subunit A
, putative amidase
, glutamyl-tRNA amidotransferase subunit A protein
, glutamyl-tRNA amidotransferase subunit A
, hematopietic transcription factor GATA-1
, GATA binding protein 1
, GATA-binding factor 1
, GATA-binding protein 1
, NF-E1 DNA-binding protein
, erythroid transcription factor
, GATA-binding protein 1 (globin transcription factor 1)
, erythroid transcription factor 1
, globin transcription factor 1
, nuclear factor, erythroid 1
, transcription factor GATA1
, GATA 1 protein
, erythroid-specific transcription factor eryf1