anti-GDNF Family Receptor alpha 1 (GFRA1) Antibodies

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. Additionally we are shipping GDNF Family Receptor alpha 1 Proteins (25) and GDNF Family Receptor alpha 1 Kits (22) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GFRA1 2674 P56159
GFRA1 25454 Q62997
GFRA1 14585 P97785
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Top anti-GDNF Family Receptor alpha 1 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated FACS, IP 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-GDNFRA Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-GDNFRA Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- GFRA1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti- GFRA1 antibody, Western blotting All lanes: Anti GFRA1  at 0.5ug/ml WB: Recombinant Human GFRA1 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 10 to 12 Days
$375.38
Details
Human Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 15 to 18 Days
$386.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GFR alpha-1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated IHC (p), WB 100 μg Log in to see 7 to 9 Days
$793.83
Details
Human Rabbit Un-conjugated WB Western Blot: GDNF Receptor alpha 1 Antibody [ABIN4089363] - Crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S), respectively, at 1:500 dilution. 0.1 mg Log in to see 7 to 9 Days
$564.38
Details

GFRA1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-GDNF Family Receptor alpha 1 Antibodies

  1. Human Monoclonal GFRA1 Primary Antibody for FACS, IP - ABIN1449286 : Müller, Tora: The multicoloured world of promoter recognition complexes. in The EMBO journal 2004 (PubMed)
    Show all 5 references for 1449286

  2. Human Monoclonal GFRA1 Primary Antibody for WB - ABIN1449285 : Udvardy: Dividing the empire: boundary chromatin elements delimit the territory of enhancers. in The EMBO journal 1999 (PubMed)
    Show all 5 references for 1449285

  3. Human Polyclonal GFRA1 Primary Antibody for IF (p) - ABIN726234 : Li, Bhave, Chow, Riera, Schlee, Rauch, Atanasova, Cate, Whitty: Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels. in The Journal of biological chemistry 2015 (PubMed)

  4. Human Polyclonal GFRA1 Primary Antibody for IF (p), IHC (p) - ABIN726230 : Ma, Zhou, Li, Zheng, Wu, Niu, Tang, He, Li, Hua: Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT. in Scientific reports 2016 (PubMed)

More Antibodies against GDNF Family Receptor alpha 1 Interaction Partners

Human GDNF Family Receptor alpha 1 (GFRA1) interaction partners

  1. RET (show RET Antibodies) c.1296A may be a common susceptibility allele for nephron underdosing-related diseases. The 5'-UTR (show UTS2R Antibodies) and intronic variants near exon 5 of GFRA1 are not associated with nephron endowment.

  2. Hox (show MSH2 Antibodies) proteins coordinate motor neuron differentiation and connectivity programs through Ret (show RET Antibodies)/Gfra genes.

  3. This study demonstrate, using a knock-in mouse model in which GFRalpha1 is no longer located in lipid rafts, that the developmental functions of GDNF (show GDNF PLURAL_@9871@) in the periphery require the translocation of the GDNF (show GDNF PLURAL_@9871@) receptor complex into lipid rafts.

  4. Methylation changes of GFRA1, SRF, and ZNF382 (show ZNF382 Antibodies) may be a potential biomarker set for prediction of gastric carcinoma metastasis.

  5. GFRalpha1 levels in neurons from autopsied AD brains are significantly decreased.

  6. These findings collectively demonstrate that GFRalpha1 released by nerves enhances perineural invasion through GDNF (show GDNF Antibodies)-RET (show RET Antibodies) signaling and that GFRalpha1 expression by cancer cells enhances but is not required for it.

  7. The study shows co-localization of RET (show RET Antibodies) with GFRA1 and GFRA2 (show GFRA2 Antibodies) in myenteric ganglia of the adult human colon.

  8. The expression of GFRalpha1 and/or GFRalpha3 (show GFRA3 Antibodies), especially when combined with ARTN (show ARTN Antibodies) expression, may be useful predictors of disease progression and outcome in specific subtypes of mammary carcinoma.

  9. Mutations in GFRA1 gene is associated with urinary tract malformations.

  10. Post-synaptic transgenic GFRalpha1 has profound effects on the development of dopamine neurons, resulting in a 40% increase in the adult number.

Mouse (Murine) GDNF Family Receptor alpha 1 (GFRA1) interaction partners

  1. The GDNF (show GDNF PLURAL_@9871@)-GFRalpha1 complex is essential for proper hippocampal circuit development.

  2. GDNF (show GDNF PLURAL_@9871@) signals were able to induce the stratified aggregate formation of GFRalpha1-positive undifferentiated spermatogonia

  3. LncRNA033862 is an antisense transcript of the GDNF (show GDNF PLURAL_@9871@) receptor alpha1 (Gfra1) that lacks protein coding potential and regulates Gfra1 expression levels by interacting with Gfra1 chromatin.

  4. These findings collectively demonstrate that GFRalpha1 released by nerves enhances perineural invasion through GDNF (show GDNF Antibodies)-RET (show RET Antibodies) signaling and that GFRalpha1 expression by cancer cells enhances but is not required for it.

  5. Gfra1 expression in the urinary tract strictly depends on cell-type and specific stage in kidney development.

  6. SorLA (show SORL1 PLURAL_@9871@) acts as sorting receptor for the GDNF (show GDNF PLURAL_@9871@)/GFRalpha1 complex, directing it from the cell surface to endosomes.

  7. our data demonstrate that RET (show RET Antibodies)/GFRalpha signals are dispensable for thymic T cell development in vivo

  8. GFRalpha1 is critical for the development and function of the main olfactory system, contributing to the development and allocation of all major classes of neurons and glial cells.

  9. Donor-derived GFRalpha1-positive cells formed several aggregates of A(al(aligned)) /morula-like structures in a single spermatogenic cell patch before and on day 14 post-transplant, indicating involvement in the formation of a stable spermatogenic colony.

  10. GFRA1 expression is regulated by GDNF (show GDNF PLURAL_@9871@) and in cultures of isolated seminiferous tubules, we found that GDNF (show GDNF PLURAL_@9871@) expression and secretion by Sertoli cells is stage-dependent, being maximal in stages II-VI and decreasing thereafter.

GDNF Family Receptor alpha 1 (GFRA1) Antigen Profile

Protein Summary

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.

Gene names and symbols associated with GFRA1

  • GDNF family receptor alpha 1 (gfra1) antibody
  • GDNF family receptor alpha 1 (GFRA1) antibody
  • GDNF family receptor alpha 1 (LOC100338839) antibody
  • GDNF family receptor alpha 1 (Gfra1) antibody
  • glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1) antibody
  • AU042498 antibody
  • GDNFR antibody
  • GDNFRA antibody
  • GDNFRALPHA antibody
  • GFR-ALPHA-1 antibody
  • GFRA1 antibody
  • MGC122616 antibody
  • RET1L antibody
  • RETL1 antibody
  • TRNR1 antibody

Protein level used designations for GFRA1

GDNF family receptor alpha 1 , GDNF family receptor alpha-1 , GDNF family receptor alpha-1-like , GDNF receptor alpha-1 , GDNFR-alpha-1 , GPI-linked anchor protein , Glial cell line-derived neurotrophic factor receptor alpha , PI-linked cell-surface accessory protein , RET ligand 1 , TGF-beta related neurotrophic factor receptor 1 , TGF-beta-related neurotrophic factor receptor 1 , GDNF receptor alpha , GDNFR-alpha , GFR-alpha-1 , glial cell line derived neurotrophic factor family receptor alpha 1 , GFR alpha-1

GENE ID SPECIES
100125202 Xenopus (Silurana) tropicalis
450756 Pan troglodytes
534801 Bos taurus
609114 Canis lupus familiaris
100338839 Oryctolagus cuniculus
100390427 Callithrix jacchus
100580436 Nomascus leucogenys
2674 Homo sapiens
25454 Rattus norvegicus
395994 Gallus gallus
14585 Mus musculus
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