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GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. Additionally we are shipping GDP Dissociation Inhibitor 1 Antibodies (83) and GDP Dissociation Inhibitor 1 Proteins (13) and many more products for this protein.
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Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA (human, human recombinant, or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA.
Human oligodendrogliomas cells stably expressing mutant GDI1 showed altered cell proliferation.
GDI1 mutations cause an unspecific phenotype characterized by cognitive deficits of variable degree in males, and to a lesser degree in female carriers.
A model by which mutant PrP (show C4BPA ELISA Kits) induces overexpression of GDI, activating a cytotoxic feedback loop that leads to protein accumulation in the secretory pathway.
RhoGDI (show ARHGDIA ELISA Kits) has a role in inactivating Rho GTPases with ExoS RhoGAP (show ARHGAP1 ELISA Kits)
isoprenylcysteine carboxylmethyltransferase (show ICMT ELISA Kits) regulates Rac1 activity by controlling the interaction of Rac1 with RhoGDI (show ARHGDIA ELISA Kits) through TNFA (show TNF ELISA Kits)
RhoGDI (show ARHGDIA ELISA Kits) overexpression is associated with paclitaxel resistance in ovarian cancers
The results of case-control analysis indicated that, no association between the rs11549300 polymorphisms of GDI1 and children NSMR (P >0.05), but its polymorphisms may be related to intelligence levels of children in Qinba region (P =0.03).
GDI-1 is preferentially involved in insulin (show INS ELISA Kits)-stimulated glucose transporter 4 (GLUT4 (show SLC2A4 ELISA Kits)) translocation through facilitating Rab10 (show RAB10 ELISA Kits) recycling.
Data confirm isolated adrenocorticotropin deficiency (IAD) as autoimmune disease; RABGDIA/Gdi1 (human or rat) exhibits characteristics of autoantigen in anterior pituitary; patients with IAD exhibit autoantibodies against RABGDIA/Gdi1.
A pivotal role of alphaGDI via specific RAB (show HRB ELISA Kits) GTPases acting specifically in forebrain regions at the pre-synaptic sites involved in memory formation.
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
rab GDP dissociation inhibitor alpha
, guanosine diphosphate dissociation inhibitor 1
, mental retardation, X-linked 48
, protein XAP-4
, rab GDI alpha
, rab GDP-dissociation inhibitor, alpha
, GDP dissociation inhibitor 2
, SMG p25A GDI
, GDP-dissociation inhibitor 1
, Rab GDIalpha