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GULP, Engulfment Adaptor PTB Domain Containing 1 Proteins (GULP1)

The protein encoded by GULP1 is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Additionally we are shipping GULP, Engulfment Adaptor PTB Domain Containing 1 Antibodies (50) and GULP, Engulfment Adaptor PTB Domain Containing 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GULP1 51454 Q9UBP9
GULP1 70676 Q8K2A1
Rat GULP1 GULP1 314543 Q5PQS4
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Top GULP, Engulfment Adaptor PTB Domain Containing 1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,795.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

GULP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Top referenced GULP, Engulfment Adaptor PTB Domain Containing 1 Proteins

  1. Human GULP1 Protein expressed in Escherichia coli (E. coli) - ABIN1098569 : Smits, Van Criekinge, Plaetinck, Bogaert: The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells. in Current biology : CB 2000 (PubMed)
    Show all 2 references for ABIN1098569

More Proteins for GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1) Interaction Partners

Human GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1) interaction partners

  1. GULP1 only mediates LRP1 (show LRP1 Proteins) transactivation

  2. The apoptotic engulfment protein Ced-6 participates in clathrin-mediated yolk uptake in Drosophila egg chambers.

  3. GULP expression positively regulates TGF-beta (show TGFB1 Proteins) signaling leading to growth inhibition, this may represent an attractive target to achieve TGF-beta (show TGFB1 Proteins) responsiveness in ovarian cells.

  4. This study identify GULP1 as a novel neuronal amyloid-beta precursor protein interacting protein that alters trafficking and processing of amyloid-beta precursor protein.

  5. overexpression of GULP1 enhanced the generation of APP (show APP Proteins) CTFs (C-terminal fragments) and Abeta (show APP Proteins), whereas knockdown of GULP1 suppressed APP (show APP Proteins) CTFs and Abeta (show APP Proteins) production.

  6. these results indicate that GULP functions as an adaptor protein for stabilin-1-mediated phagocytosis.

  7. the GULP1 gene and the apoptotic engulfment pathway are involved in schizophrenia in subjects of European ancestry

  8. Interaction of CED-6/GULP, an adapter protein (show TOLLIP Proteins) involved in engulfment of apoptotic cells with CED-1 (show IFT122 Proteins) and CD91 (show LRP1 Proteins)/low density lipoprotein receptor (show LDLR Proteins)-related protein (LRP (show LRP1 Proteins)).

  9. GULP is a likely downstream molecule in the stabilin-2 (show STAB2 Proteins)-mediated signaling pathway and plays an important role in stabilin-2 (show STAB2 Proteins)-mediated phagocytosis

  10. Phosphatidylserine-recognizing SR-BI activates associated GULP; activated GULP induces MAPK phosphorylation; activated MAPK increases GTP-bound Rac1; and activated Rac1 induces a rearrangement of the actin cytoskeleton.

Mouse (Murine) GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1) interaction partners

  1. Jedi-1 (show PEAR1 Proteins) signals through recruitment of GULP, which promotes phagocytosis through a noncanonical phosphoclathrin-dependent mechanism.

  2. in this study we report the identification of a novel C. elegans CED-6-like orthologue in mouse, which has probable apoptotic like function

  3. Phosphatidylserine-recognizing SR-BI activates associated GULP; activated GULP induces MAPK phosphorylation; activated MAPK increases GTP-bound Rac1; and activated Rac1 induces a rearrangement of the actin cytoskeleton.

GULP, Engulfment Adaptor PTB Domain Containing 1 (GULP1) Protein Profile

Protein Summary

The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene.

Gene names and symbols associated with GULP1

  • GULP, engulfment adaptor PTB domain containing 1 (GULP1)
  • GULP, engulfment adaptor PTB domain containing 1 (gulp1)
  • CED-6 protein (Bm1_18525)
  • ced-6 protein (ced-6)
  • GULP, engulfment adaptor PTB domain containing 1 (Gulp1)
  • GULP, engulfment adaptor PTB domain containing 1a (gulp1a)
  • 3110030A04Rik protein
  • 5730529O06Rik protein
  • CED-6 protein
  • Ced6 protein
  • GULP protein
  • Gulp-2 protein
  • gulp1 protein
  • si:by35d8.1 protein
  • si:ch211-198b21.4 protein
  • si:xx-35d8.1 protein
  • wu:fj61e02 protein

Protein level used designations for GULP1

GULP, engulfment adaptor PTB domain containing 1 , PTB domain adaptor protein CED-6 , ptb domain-containing engulfment adapter protein 1 , CED-6 protein , ced-6 protein , PTB domain adapter protein CED-6 , PTB domain-containing engulfment adapter protein 1 , cell death protein 6 homolog , engulfment adapter protein , CED 6

GENE ID SPECIES
423988 Gallus gallus
459812 Pan troglodytes
478834 Canis lupus familiaris
615926 Bos taurus
100528822 Ictalurus punctatus
6098612 Brugia malayi
100415789 Bombyx mori
51454 Homo sapiens
70676 Mus musculus
314543 Rattus norvegicus
368404 Danio rerio
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