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anti-General Transcription Factor IIE, Polypeptide 2, beta 34kDa (GTF2E2) Antibodies

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH.

list all antibodies Gene Name GeneID UniProt
Anti-Mouse GTF2E2 GTF2E2 68153 Q9D902
Anti-Rat GTF2E2 GTF2E2 306516  
Anti-Human GTF2E2 GTF2E2 2961 P29084
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More Antibodies against General Transcription Factor IIE, Polypeptide 2, beta 34kDa Interaction Partners

Human General Transcription Factor IIE, Polypeptide 2, beta 34kDa (GTF2E2) interaction partners

  1. We underline role of TFIIE in transcription and its distinction from nucleotide excision repair. Trichothiodystrophy individuals with mutations in GTF2E2 highlight the importance of the direct interaction between TFIIH (show GTF2H1 Antibodies) and TFIIE in transcription process.

  2. PC4 (show IFRD1 Antibodies) plays essential roles in the transition step from transcription initiation to elongation by binding to melted DNA in collaboration with TFIIEbeta.

  3. introduced point mutations into two regions located near the carboxy terminus of TFIIE beta and identified the functionally essential amino acid residues that bind to RNA polymerase II

  4. TFIIE is an alpha/beta heterodimer in solution; A model for the quaternary architecture of the complex is proposed that provides a structural framework to discuss the function of TFIIE in the context of RNA polymerase II transcription initiation.

  5. These data suggest a model in which TFIIE binds to a position adjacent to the initiation site via the forkhead domain, enabling TFIIH (show GTF2H1 Antibodies) to begin opening the promoter.

General Transcription Factor IIE, Polypeptide 2, beta 34kDa (GTF2E2) Antigen Profile

Protein Summary

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

Gene names and symbols associated with GTF2E2

  • general transcription factor II E, polypeptide 2 (beta subunit) (Gtf2e2) antibody
  • general transcription factor IIE, polypeptide 2, beta (gtf2e2) antibody
  • general transcription factor IIE, polypeptide 2, beta (Gtf2e2) antibody
  • general transcription factor IIE, polypeptide 2, beta 34kDa (GTF2E2) antibody
  • general transcription factor IIE, polypeptide 2, beta 34kDa (gtf2e2) antibody
  • 34kDa antibody
  • AI462509 antibody
  • C330006J08Rik antibody
  • FE antibody
  • TF2E2 antibody
  • TFIIE-B antibody
  • wu:fa05d01 antibody
  • zgc:77074 antibody

Protein level used designations for GTF2E2

TFIIE-beta , general transcription factor II E, polypeptide 2 (beta subunit, 34kD) , general transcription factor IIE subunit 2 , general transcription factor IIE, polypeptide 2 (beta subunit, 34kD) , transcription initiation factor IIE subunit beta , general transcription factor II E, polypeptide 2 (beta subunit) , general transcription factor IIE, polypeptide 2 (beta subunit)

GENE ID SPECIES
68153 Mus musculus
334854 Danio rerio
306516 Rattus norvegicus
771227 Gallus gallus
2961 Homo sapiens
510921 Bos taurus
734303 Xenopus laevis
475597 Canis lupus familiaris
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