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Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) ELISA Kits

GAD2 encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. Additionally we are shipping GAD65 Antibodies (180) and GAD65 Proteins (17) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GAD2 24380 Q05683
GAD2 2572 Q05329
GAD2 14417 P48320
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Top GAD65 ELISA Kits at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.23 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Rat 0.09 ng/mL 0.16-10 ng/mL Diagramm of the ELISA kit to detect Rat GAD 2with the optical density ... 96 Tests Log in to see 8 to 9 Days
$680.63
Details
Mouse
  96 Tests Log in to see 8 to 9 Days
$680.63
Details
Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
Details
Chicken
  96 Tests Log in to see 8 to 9 Days
$770.00
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Monkey
  96 Tests Log in to see 8 to 9 Days
$770.00
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Rabbit
  96 Tests Log in to see 8 to 9 Days
$770.00
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Human
  96 Tests Log in to see 11 to 13 Days
$785.71
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Pig
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Dog
  96 Tests Log in to see 11 to 13 Days
$1,095.60
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More ELISA Kits for GAD65 Interaction Partners

Rhesus Monkey Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) interaction partners

  1. Results describe the gross distribution patterns of GAD65 in human and rhesus monkey thalami and show that they are nearly identical.

Zebrafish Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) interaction partners

  1. GAD65 mRNA was found in the periaqueductal gray.

Human Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) interaction partners

  1. UV exposed hydrogen peroxide produces hydroxyl radical that may cause protein damage (GAD-65) to the extent of generating neo-epitopes on the molecule, making it immunogenic.

  2. we investigated the relationship between serum glutamic acid decarboxylase (GAD (show GAD ELISA Kits)) autoantibody (Ab) levels and single nucleotide polymorphisms (SNPs) of the glutamic acid de-carboxylase 2 (GAD2) 5'-untranslated region

  3. GAD (show GAD1 ELISA Kits) autoantibodies were associated with risk of developing type 1 diabetes.

  4. Kaplan-Meier survival curves estimated a worst pancreas graft survival for patients with positive IA-2 (show PTPRN ELISA Kits) antibodies versus those patients with negative auto-antibodies and GAD65+ auto-antibodies after simultaneous pancreas kidney transplantation.

  5. Plasma GAD65 qualifies as a marker for early beta-cell loss after intraportal transplantation.

  6. Cohort study shows that mean GAD65 mRNA levels in the prefrontal cortex area 9 are not altered in subjects with schizophrenia but are lower in subjects with schizoaffective disorder

  7. Data suggest that women with gestational diabetes who develop autoantibodies against GAD2 (glutamate decarboxylase 2) exhibit higher blood glucose levels, insulin (show INS ELISA Kits) resistance, and impaired insulin (show INS ELISA Kits) secretion from beta cells in the postpartum period.

  8. Phosphate-activated glutaminase (show GLS2 ELISA Kits) and GAD65/67 concentrations are compared in Alzheimer's disease cerebellum versus normal cerebellum controls

  9. GAD2 SNPs significantly associate with early-onset obsessive compulsive disorder.

  10. The decreased amount of GAD65 and GAD67 (show GAD1 ELISA Kits) suggests the decreased synthesis of neurotransmitter and basic GABA pools that indicates insufficient functioning of the GABA system in the cerebellar cortex of Alzheimer's disease patients.

Mouse (Murine) Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) interaction partners

  1. Increased activity due to bicuculline preferentially up-regulated GAD65. This was reduced by AP5 (show AP5B1 ELISA Kits), a selective blocker of Ca2 (show CA2 ELISA Kits)+-permeable ion channels and NMDA-Rs, and by U0126, KN93, and K252a, affecting BDNF (show BDNF ELISA Kits) pathways.

  2. Data show that miRNAs are involved in regulating the expression of the major type 1 diabetes (T1D) autoantigens IA-2 (show PTPRN ELISA Kits), IA-2beta (show PTPRN2 ELISA Kits), and GAD65 enzyme.

  3. Results indicate the significant contribution of not only GAD65, GAD67 (show GAD1 ELISA Kits) and VGAT (show SLC32A1 ELISA Kits)-mediated GABAergic but also glycinergic transmissions to both palate and abdominal wall formations

  4. Analysis of GAD65/67 single and double knock-out embryos revealed that the two GADs play complementary (inhibitory) roles in GnRH migration ultimately modulating the speed and/or direction of GnRH migration.

  5. Results show that GAD65 is required for efficient GABAergic synaptic transmission and plasticity, and for maintaining extracellular GABA at (show ABAT ELISA Kits) a level needed for associative plasticity at cortical inputs in the lateral amygdala

  6. Menin (show MEN1 ELISA Kits) regulates spinal glutamate (show GRIN1 ELISA Kits)-GABA balance through GAD65 contributing to neuropathic pain.

  7. Our data suggest a role of GAD65-mediated GABA synthesis in the encoding of circadian information to fear memory

  8. Autoimmunity to GAD65 may play a role in the development of Stiff person syndrome.

  9. Prenatal and postnatal maternal effects influence GAD65 and GAD67 (show GAD1 ELISA Kits) gene expression depending on the age of the offspring.

  10. These findings indicate novel, differential roles for GluN2A (show GRIN2A ELISA Kits), B and D receptors and for GAD65-mediated GABA in the regulation of individual topographies of orofacial movement

GAD65 (GAD2) Antigen Profile

Antigen Summary

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with GAD2

  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2) antibody
  • glutamate decarboxylase 2 (GAD2) antibody
  • glutamate decarboxylase 2 (PTRG_06148) antibody
  • glutamate decarboxylase 2 (ARALYDRAFT_894224) antibody
  • glutamate decarboxylase 2 (Gad2) antibody
  • glutamate decarboxylase 2 (LOC100344727) antibody
  • glutamate decarboxylase 2 (gad2) antibody
  • glutamic acid decarboxylase 2 (Gad2) antibody
  • 6330404F12Rik antibody
  • F12P19.12 antibody
  • F12P19_12 antibody
  • GAD(65) antibody
  • Gad-2 antibody
  • gad65 antibody
  • glutamate decarboxylase 2 antibody
  • zgc:112198 antibody

Protein level used designations for GAD2

glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) , glutamate decarboxylase 2 , glutamic acid decarboxylase , 65 kDa glutamic acid decarboxylase , GAD-65 , Glutamate decarboxylase 2 (islet) , glutamate decarboxylase 65 kDa isoform , glutamic acid decarboxylase 2 , glutamic acid decarboxylase 65 , Glutamate decarboxylase-2 (pancreas)

GENE ID SPECIES
466026 Pan troglodytes
512459 Bos taurus
613029 Macaca mulatta
4836947 Scheffersomyces stipitis CBS 6054
6344405 Pyrenophora tritici-repentis Pt-1C-BFP
9324534 Arabidopsis lyrata subsp. lyrata
24380 Rattus norvegicus
100344727 Oryctolagus cuniculus
842908 Arabidopsis thaliana
550403 Danio rerio
2572 Homo sapiens
487107 Canis lupus familiaris
395395 Gallus gallus
396929 Sus scrofa
14417 Mus musculus
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