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N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. Additionally we are shipping NMDAR2A Kits (24) and NMDAR2A Proteins (9) and many more products for this protein.
Showing 10 out of 225 products:
Mouse (Murine) Monoclonal NMDAR2A Primary Antibody for IF, WB - ABIN968802
Ishii, Moriyoshi, Sugihara, Sakurada, Kadotani, Yokoi, Akazawa, Shigemoto, Mizuno, Masu: Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits. in The Journal of biological chemistry 1993
Show all 2 references for ABIN968802
Human Monoclonal NMDAR2A Primary Antibody for IHC, WB - ABIN2483898
Teng, Cai, Zhou, Zhang, Liu, Wang, Dai, Zhao, Sun: Evolutionary mode and functional divergence of vertebrate NMDA receptor subunit 2 genes. in PLoS ONE 2010
Human Polyclonal NMDAR2A Primary Antibody for IHC, WB - ABIN2776120
Kim, Chang, Nagpal, Yamashita, Baek, Dasgupta, Wu, Osada, Woo, Westra, Trink, Ratovitski, Moon, Sidransky: The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth. in Oncogene 2008
Rat (Rattus) NMDAR2A Primary Antibody for ELISA, WB - ABIN1742591
Wang, Liu, Fu, Wang, Lu: Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors. in Nature neuroscience 2003
Human Polyclonal NMDAR2A Primary Antibody for IF (p), IHC (p) - ABIN747353
Zhao, Li, Wei, Savage, Zhou, Ma: Ketamine administered to pregnant rats in the second trimester causes long-lasting behavioral disorders in offspring. in Neurobiology of disease 2014
Knockdown of PKD1 (show PKD1 Antibodies) did not affect NMDAR (show GRIN1 Antibodies) internalization but prevented the phosphorylation and inhibition of remaining surface NMDARs and NMDAR (show GRIN1 Antibodies)-mediated synaptic functions.
Findings suggest that mutations in GRIN2A preferentially are involved in genetic variance of pediatric idiopathic generalized epilepsy and do not contribute significantly to either adult focal epilepsies as temporal lobe epilepsy or generalized epilepsies
Based on large, well-characterized datasets independent from the original study, our results are not in favor of an interaction between caffeinated coffee consumption and GRIN2A rs4998386 for Parkinson disease risk
Study found GluN receptor subunit-specific changes in mixed subcortical ischemic vascular dementia(SIVD)/Alzheimer's disease(AD) (decreased GluN1 (show GRIN1 Antibodies)) and SIVD (increased GluN2A and 2B), likely reflecting interaction of ischemic neurovascular and AD processes
NMDARs have a dual role during erythropoiesis, supporting survival of polychromatic erythroblasts and contributing to the Ca(2 (show CA2 Antibodies)+) homeostasis from the orthochromatic erythroblast stage to circulating red blood cells.
GRIN2A (GT)21 may play a significant role in the etiology of schizophrenia among the Chinese Han population of Shaanxi.
GRIN2A gene polymorphisms confer susceptibility to heroin addiction.
Dysarthria and dyspraxia are found in individuals with GRIN2A mutations, often in the setting of epilepsy-aphasia syndromes. The speech phenotype may occur in the absence of a seizure disorder, reinforcing the role for GRIN2A in motor speech function.
We demonstrate the functional importance of GRIN2A mutations in melanoma and the significance that ionotropic glutamate (show GRIN1 Antibodies) receptor signaling has in malignant melanoma.
Results show that the expression and distribution of NMDA receptors subunits GluN1 (show GRIN1 Antibodies), GluN2A and GluN2B (show GRIN2B Antibodies) - together with that of postsynaptic protein PSD-95 (show DLG4 Antibodies) - are modified in Alzheimer's disease compared to normal aging
Rph3A (show RPH3A Antibodies) interacts with GluN2A and PSD-95 (show DLG4 Antibodies) forming a complex that regulates NMDARs stabilization at postsynaptic membranes.
Egr-1 (show EGR1 Antibodies) is involved in NMDAR (show GRIN1 Antibodies)-mediated PSD-95 (show DLG4 Antibodies) down-regulation and AMPAR endocytosis, a process important in the expression of long term depression
Study demonstrated that GluN2A carboxy-terminal domain is responsible for the impaired long-term olfactory and social memory observed in the GluN2A overexpression mice
Results establish the GluN2A subunit as a significant contributor to both bidirectional synaptic plasticity and spatial pattern separation in the dentate gyrus
Best1 (show BEST1 Antibodies)-mediated astrocytic glutamate (show GRIN1 Antibodies) activates the synaptic N-methyl-D-aspartate receptor (show GRIN1 Antibodies) (NMDAR (show GRIN1 Antibodies)) and modulates NMDAR (show GRIN1 Antibodies)-dependent synaptic plasticity.
Data suggest a role for GluN2A in ethanol tolerance.
We conclude that TSPYL2 (show TSPYL2 Antibodies) contributes to cognitive variability through regulating the expression of Grin2a and Grin2b (show GRIN2B Antibodies).
Results suggest that GluN2B (show GRIN2B Antibodies) is essential for the survival of animals, and that the GluN2B (show GRIN2B Antibodies)-GluN2A switching plays a critical role in synaptic integration of AMPARs through regulation of GluA1 (show GRIA1 Antibodies) in the whole animal.
GluN2A KO mice showed a specific and significant impairment in ventromedial prefrontal cortex-mediated set-shifting.
Deletion of the NMDA receptor GluN2A subunit significantly decreases dendritic growth in maturing dentate granule neurons.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
N-methyl-D-aspartate receptor subunit NR2A
, glutamate receptor, ionotropic, N-methyl D-aspartate 2A
, glutamate [NMDA] receptor subunit epsilon-1-like
, N-methyl D-aspartate receptor subtype 2A
, N-methyl-D-aspartate receptor channel, subunit epsilon-1
, N-methyl-D-aspartate receptor subunit 2A
, NMDA receptor subtype 2A
, glutamate [NMDA] receptor subunit epsilon-1
, glutamate receptor ionotropic, NMDA 2A
, glutamate [NMDA] receptor subunit epsilon 1
, glutamate receptor, ionotropic, N-methyl-D-aspartate subunit 2A