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Glutathione Peroxidase 2 (GPX2) ELISA Kits

GPX2 is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Additionally we are shipping Glutathione Peroxidase 2 Antibodies (34) and Glutathione Peroxidase 2 Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GPX2 14776 Q9JHC0
GPX2 29326  
GPX2 2877 P18283
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Top Glutathione Peroxidase 2 ELISA Kits at antibodies-online.com

Showing 3 out of 12 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 6.25 pg/ml 25-1600 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Rat 0.039 ng/ml 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 0.078 ng/ml 0.312-20 ng/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for Glutathione Peroxidase 2 Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) Glutathione Peroxidase 2 (GPX2) interaction partners

  1. The authors cloned cytosolic glutathione peroxidase (GPx1 (show GPX1 ELISA Kits)) and phospholipid hydroperoxide glutathione peroxidase (GPx4) genes in rainbow trout (Oncorhynchus mykiss). Constitutive mRNA expression and responsiveness to Se availability was analysed.

Mouse (Murine) Glutathione Peroxidase 2 (GPX2) interaction partners

  1. High glutathione peroxidase 2 expression is associated with radiation induced lung disease.

  2. we propose that ileocolitis in the GPx1 (show GPX1 ELISA Kits)/2-double-knockout mice is caused by Nox1 (show NOX1 ELISA Kits), which is induced by TNF (show TNF ELISA Kits)

  3. GPx2 is up-regulated in dysplastic colonic crypts, where it appears to act inhibit apoptosis and, thus, supports tumor development.

  4. Candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 (show GPX1 ELISA Kits) and -2, were analyzed.

  5. it is concluded that GPx2, although supporting tumor growth, inhibits inflammation-mediated tumorigenesis, but the protective effect of selenium does not strictly depend on GPx2 expression

  6. study indicates GI-GPx is spatiotemporally expressed in embryonic organs during organogenesis and may also perform a mutual compensatory role with cGPx (show GPX1 ELISA Kits) in protecting embryos and extraembryonic tissues against reactive oxygen species

  7. Loss of Gpx2 is associated with diet induced severe colitis.

  8. In GPx2 KO mice, an increase in GPx1 (show GPX1 ELISA Kits) can only partially compensate for GPx2, even under selenium supplementation, indicating that GPx2 is the major antiapoptotic GPx (show PRDX6 ELISA Kits) in the colon.

  9. Genes encoding the antioxidants GPX2 and GSTO 1-1 (show GSTO1 ELISA Kits) are common inflammatory genes expressed upon induction of allergic airway inflammation, and independently of allergic susceptibility.

  10. GPX1 (show GPX1 ELISA Kits)-DKO and GPX2-DKO mice are highly susceptible to bacteria-associated inflammation and cancer.

Human Glutathione Peroxidase 2 (GPX2) interaction partners

  1. GPX2 underexpression is associated with advanced tumor status and implicated unfavorable clinical outcome of UCs, suggesting its role in tumor progression and may serve as a theranostic biomarker of UCs.

  2. high GPx2 expression was associated with early tumor recurrence, particularly in the recently identified aggressive subtype of human colon cancer.

  3. Patients with high GPX2 expression in biopsy specimen had significantly lower prostate-specific antigen recurrence-free survival and overall survival than those with no GPX2 expression.

  4. miR (show MLXIP ELISA Kits)-185 plays a role in up-regulation of GPX2 and SEPHS2 (show SEPHS2 ELISA Kits) expression.

  5. A role of GPx2, TrxR2 (show TXNRD2 ELISA Kits) and TrxR3 (show TXNRD3 ELISA Kits) in proliferation, apoptosis and, therefore, also during cancer development.

  6. A GPx2-independent decrease in tumor development by selenium (Se) and detrimental effects of the Nrf2 (show GABPA ELISA Kits)-activator sulforaphane in moderate Se deficiency.

  7. Cellular and subcellular localization of gastrointestinal glutathione peroxidase in normal and malignant human intestinal tissue

  8. Data suggest that some antioxidants may exert their anti-inflammatory and anticarcinogenic effects not only by induction of phase 2 enzymes but also by the up-regulation of the selenoprotein GI-GPx by Nrf2 (show GABPA ELISA Kits) binding.

  9. some isoforms of p63 (show RPE65 ELISA Kits) serve as a pro-survival factor by up-regulating GPX2 to reduce the p53 (show TP53 ELISA Kits)-dependent oxidative stress-induced (show SQSTM1 ELISA Kits) apoptotic response

  10. Glutathione peroxidase 2 (GPX2) is the major oxidative stress-inducible cellular GPX (show GPX1 ELISA Kits) isoform in the lungs, and its basal as well as inducible expression is dependent on Nrf2 (show GABPA ELISA Kits).

Glutathione Peroxidase 2 (GPX2) Antigen Profile

Antigen Summary

This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. The protein encoded by this locus contains a selenocysteine (Sec) residue encoded by the UGA codon, which normally signals translation termination. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with GPX2

  • glutathione peroxidase type 2 (LOC100136264) antibody
  • glutathione peroxidase 2 (gastrointestinal) (GPX2) antibody
  • glutathione peroxidase 2 (LELG_01052) antibody
  • glutathione peroxidase 2 (Gpx2) antibody
  • GI-GPx antibody
  • GPRP antibody
  • GPRP-2 antibody
  • GPx-2 antibody
  • GPX-GI antibody
  • GSHPx-2 antibody
  • GSHPX-GI antibody
  • LOC100136264 antibody

Protein level used designations for GPX2

glutathione peroxidase type 2 , glutathione peroxidase 2 , GPx-2 , glutathione peroxidase-gastrointestinal , intestinal GPx , gastrointestinal glutathione peroxidase , glutathione peroxidase-related protein 2

GENE ID SPECIES
100136264 Oncorhynchus mykiss
467483 Pan troglodytes
708429 Macaca mulatta
5234988 Lodderomyces elongisporus NRRL YB-4239
14776 Mus musculus
29326 Rattus norvegicus
2877 Homo sapiens
480356 Canis lupus familiaris
767625 Sus scrofa
533088 Bos taurus
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