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The protein encoded by GNRH1 is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). Additionally we are shipping GNRH1 Kits (67) and GNRH1 Proteins (24) and many more products for this protein.
Showing 10 out of 105 products:
Atlantic Hagfish (Myxine glutinosa) Polyclonal GNRH1 Primary Antibody for IEM, ICC - ABIN617888
Masucci, DAniello, Iela, Ciarcia, Rastogi: Immunohistochemical demonstration of the presence and localization of diverse molecular forms of gonadotropin-releasing hormone in the lizard (Podarcis s. sicula) brain. in General and comparative endocrinology 1992
Show all 75 references for ABIN617888
Hormone Polyclonal GNRH1 Primary Antibody for ELISA - ABIN93570
Guzmán, Norberg, Ramos, Mylonas, Mañanós: Vitellogenin, steroid plasma levels and spawning performance of cultured female Senegalese sole (Solea senegalensis). in General and comparative endocrinology 2008
Goat Polyclonal GNRH1 Primary Antibody for IF (cc), IF (p) - ABIN668841
Liu, Chang, Sun, Zhu, Pu, Zhu, Wang, Xu: Ultrasound-mediated destruction of LHRHa-targeted and paclitaxel-loaded lipid microbubbles induces proliferation inhibition and apoptosis in ovarian cancer cells. in Molecular pharmaceutics 2014
findings suggest that GnRH is necessary for constitutive ANXA5 (show ANXA5 Antibodies) expression in the pituitary gland, not only in gonadotropes but also in other pituitary gland cell types
In this study, we investigate the mechanism by which VAX1 controls fertility finding that VAX1 is required for maintenance of Gnrh1 gene expression and deletion of Vax1 from GnRH neurons leads to complete infertility.
RALDH and RA might not be directly involved in the reduction of GnRH expression induced by TSA, however these substances could be a novel regulator of GnRH.
The profound effect of Sirt1 (show SIRT1 Antibodies) on the hormonal status of Sirt1 (show SIRT1 Antibodies)(-/-) mice, mediated via defective GnRH neuronal migration, links energy metabolism directly to the hypogonadal state.
neural circuits between kisspeptin and GnRH neurons in the male mouse arcuate nucleus of the hypothalamus established before birth
Results demonstrate defective negative feedback in global Gpr54 (show KISS1R Antibodies)-null mice that cannot be attributed to a lack of prior exposure of the gonadotropin-releasing hormone neuronal network to cyclical estradiol
Although levels of H2BK120ub are increased by GnRH in the coding regions of these genes, levels at the promoters do not correlate with those of H3K4me3, nor with gene expression
Class IIa HDAC9 interact with Class IIb HDAC6 to modulate cell movement and survival in GnRH neurons
Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice.
The aims of this study were to explore whether mRNA-levels of gonadotropin-releasing hormone (Gnrh) and its receptor (Gnrhr (show GNRHR Antibodies)) were changed in plaque-bearing Alzheimer's disease transgenic mice.
Guinea pig GnRH is predominantly present in the brain and has a lower in vivo luteinizaing hormone (LH)-releasing activity than Gnrh of the rat.
GnRH regulates trophoblast invasion via RUNX2 (show RUNX2 Antibodies)-mediated MMP2 (show MMP2 Antibodies)/MMP9 (show MMP9 Antibodies) expression.
our results showed that GnRH participates in the self-renewal capacity and stemness maintenance of LCSLCs by upregulating the JNK signaling pathway, and GnRH may be useful as an alternative lung cancer stem-like cells therapy.
Melatonin affects the secretion of GnRH, LH and testosterone, improves sperm quality thereby regulating the testicular development and male reproduction. (Review)
Data suggest differences in regulation of expression of PEDF (show SERPINF1 Antibodies) (up-regulation) vs. VEGF (show VEGFA Antibodies) (down-regulation) in granulosa cells explain reduced risk of ovarian hyperstimulation syndrome due to ovulation induction using GnRH/GNRHR (show GNRHR Antibodies) agonists rather than hCG (show CGA Antibodies).
No abnormalities were found in the patient group for the PROKR2 (show PROKR2 Antibodies) and GNRH1genes. In addition, no genomic rearrangements were identified in the healthy control individuals for the described genes
Data indicate that the gene expression pattern is profoundly different between human chorionic gonadotropin (hCG) and gonadotropin-releasing hormone (GnRH) agonist.
GnRH agonists fail to increase Bax (show BAX Antibodies) expression and do not potentiate the cytotoxic activity of docetaxel
GnRH, through heterotopic expression of its receptor, may be a potential regulator of CYP11B2 (show CYP11B2 Antibodies) expression levels in some cases of aldosterone-producing adenoma.
This review will summarize the current understanding of the mechanisms by which PACAP modulates gonadotrope function, with a focus on interactions with GnRH.
findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion
Posterior hypothalamic lesion animals had elevated LHRH levels and higher evening glutamate (show GRIN2C Antibodies) levels after lesions, whereas LHRH changes did not occur in sham/controls until later.
Estradiol(E2) induces a rapid excitatory effect on primate LHRH neurons, and this rapid action of E2 appears to be mediated, in part, through GPR30 (show GPER Antibodies).
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene.
gonadotropin releasing hormone 2
, luteinizing hormone-releasing hormone I
, progonadoliberin I
, luteinizing hormone-releasing hormone
, GnRH-associated peptide 1
, gonadotropin-releasing hormone 1 (leutinizing-releasing hormone)
, luliberin I
, prolactin release-inhibiting factor
, gonadotropin releasing hormone 1
, gonadotropin-releasing hormone associated peptide
, chicken gonadotrophin releasing hormone-I
, gonadotrophin-releasing hormone I
, progonadoliberin-1 preproprotein
, Progonadoliberin I