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Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) Proteins (GNRH1)

The protein encoded by GNRH1 is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). Additionally we are shipping GNRH1 Antibodies (101) and GNRH1 Kits (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GNRH1 14714 P13562
GNRH1 2796 P01148
GNRH1 25194 P07490
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Top GNRH1 Proteins at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Clarias gariepinus His tag   1 mg Log in to see 56 to 66 Days
$2,047.83
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Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$2,053.33
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Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,060.67
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Yeast Lithobates catesbeiana His tag   1 mg Log in to see 56 to 66 Days
$2,069.83
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Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,069.83
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Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,075.33
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,079.00
Details

GNRH1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , , , ,
,
Rat (Rattus)

More Proteins for Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) Interaction Partners

Mouse (Murine) Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. findings suggest that GnRH is necessary for constitutive ANXA5 (show ANXA5 Proteins) expression in the pituitary gland, not only in gonadotropes but also in other pituitary gland cell types

  2. In this study, we investigate the mechanism by which VAX1 controls fertility finding that VAX1 is required for maintenance of Gnrh1 gene expression and deletion of Vax1 from GnRH neurons leads to complete infertility.

  3. RALDH and RA might not be directly involved in the reduction of GnRH expression induced by TSA, however these substances could be a novel regulator of GnRH.

  4. The profound effect of Sirt1 (show SIRT1 Proteins) on the hormonal status of Sirt1 (show SIRT1 Proteins)(-/-) mice, mediated via defective GnRH neuronal migration, links energy metabolism directly to the hypogonadal state.

  5. neural circuits between kisspeptin and GnRH neurons in the male mouse arcuate nucleus of the hypothalamus established before birth

  6. Results demonstrate defective negative feedback in global Gpr54-null mice that cannot be attributed to a lack of prior exposure of the gonadotropin-releasing hormone neuronal network to cyclical estradiol

  7. Although levels of H2BK120ub are increased by GnRH in the coding regions of these genes, levels at the promoters do not correlate with those of H3K4me3, nor with gene expression

  8. Class IIa HDAC9 interact with Class IIb HDAC6 to modulate cell movement and survival in GnRH neurons

  9. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice.

  10. The aims of this study were to explore whether mRNA-levels of gonadotropin-releasing hormone (Gnrh) and its receptor (Gnrhr (show GNRHR Proteins)) were changed in plaque-bearing Alzheimer's disease transgenic mice.

Guinea Pig Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. Guinea pig GnRH is predominantly present in the brain and has a lower in vivo luteinizaing hormone (LH)-releasing activity than Gnrh of the rat.

Human Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. GnRH regulates trophoblast invasion via RUNX2 (show RUNX2 Proteins)-mediated MMP2 (show MMP2 Proteins)/MMP9 (show MMP9 Proteins) expression.

  2. our results showed that GnRH participates in the self-renewal capacity and stemness maintenance of LCSLCs by upregulating the JNK signaling pathway, and GnRH may be useful as an alternative lung cancer stem-like cells therapy.

  3. Melatonin affects the secretion of GnRH, LH and testosterone, improves sperm quality thereby regulating the testicular development and male reproduction. (Review)

  4. Data suggest differences in regulation of expression of PEDF (show SERPINF1 Proteins) (up-regulation) vs. VEGF (show VEGFA Proteins) (down-regulation) in granulosa cells explain reduced risk of ovarian hyperstimulation syndrome due to ovulation induction using GnRH/GNRHR (show GNRHR Proteins) agonists rather than hCG (show CGA Proteins).

  5. No abnormalities were found in the patient group for the PROKR2 (show PROKR2 Proteins) and GNRH1genes. In addition, no genomic rearrangements were identified in the healthy control individuals for the described genes

  6. Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in humans and mice.

  7. Data indicate that the gene expression pattern is profoundly different between human chorionic gonadotropin (hCG) and gonadotropin-releasing hormone (GnRH) agonist.

  8. GnRH agonists fail to increase Bax (show BAX Proteins) expression and do not potentiate the cytotoxic activity of docetaxel

  9. GnRH, through heterotopic expression of its receptor, may be a potential regulator of CYP11B2 (show CYP11B2 Proteins) expression levels in some cases of aldosterone-producing adenoma.

  10. This review will summarize the current understanding of the mechanisms by which PACAP modulates gonadotrope function, with a focus on interactions with GnRH.

Rhesus Monkey Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) interaction partners

  1. findings report the changes in inhibin-alpha subunit gene expression in the corpus luteum is regulated by LH; results suggest a possible multiple crosstalk of Wnt, cAMP, and SF-1 in the regulation of luteal inhibin secretion

  2. Posterior hypothalamic lesion animals had elevated LHRH levels and higher evening glutamate (show GRIN2C Proteins) levels after lesions, whereas LHRH changes did not occur in sham/controls until later.

  3. Estradiol(E2) induces a rapid excitatory effect on primate LHRH neurons, and this rapid action of E2 appears to be mediated, in part, through GPR30.

GNRH1 Protein Profile

Protein Summary

The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene.

Gene names and symbols associated with GNRH1

  • gonadotropin releasing hormone 1 (Gnrh1)
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) (GNRH1)
  • gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) (Gnrh1)
  • CGNRH-I protein
  • GnRH protein
  • GnRH-I protein
  • Gnrh2 protein
  • Gnrha protein
  • GRH protein
  • HH12 protein
  • hpg protein
  • Lhrh protein
  • Lhrh1 protein
  • LNRH protein
  • Rgnrhg1 protein

Protein level used designations for GNRH1

gonadotropin releasing hormone 2 , hypogonadal , luteinizing hormone-releasing hormone I , progonadoliberin I , progonadoliberin-1 , luteinizing hormone-releasing hormone , GnRH-associated peptide 1 , gonadotropin-releasing hormone 1 (leutinizing-releasing hormone) , luliberin I , prolactin release-inhibiting factor , gonadotropin releasing hormone 1 , gonadotropin-releasing hormone associated peptide , chicken gonadotrophin releasing hormone-I , gonadotrophin-releasing hormone I , Progonadoliberin-1 , progonadoliberin-1 preproprotein , Progonadoliberin I

GENE ID SPECIES
14714 Mus musculus
100135531 Cavia porcellus
2796 Homo sapiens
25194 Rattus norvegicus
397516 Sus scrofa
770134 Gallus gallus
443529 Ovis aries
613033 Macaca mulatta
101111690 Ovis aries
101832723 Mesocricetus auratus
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