You are viewing an incomplete version of our website. Please click to reload the website as full version.

Granzyme K (Granzyme 3, Tryptase II) Proteins (GZMK)

GZMK product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Additionally we are shipping Granzyme K (Granzyme 3, Tryptase II) Antibodies (54) and Granzyme K (Granzyme 3, Tryptase II) Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GZMK 14945 O35205
GZMK 29165 P49864
GZMK 3003 P49863
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Granzyme K (Granzyme 3, Tryptase II) Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$563.20
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,588.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 11 to 16 Days
$783.93
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details

GZMK Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,
,

More Proteins for Granzyme K (Granzyme 3, Tryptase II) (GZMK) Interaction Partners

Mouse (Murine) Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. The data suggest that T-killer cells control lymphocytic choriomeningitis virus through non-cytotoxic processes that involve gzmK.

  2. It was suggested that a high predisposition to catalepsy in mice can be defined by the Map3k1 (show MAP3K1 Proteins), Il6st (show IL6ST Proteins), Gzmk, and Hspb3 (show HSPB3 Proteins) genes' coexpression network.

  3. GzmK-induced caspase (show CASP3 Proteins)-independent death occurs through Bid (show BID Proteins)-dependent mitochondrial damage that is different from GzmA (show GZMA Proteins)

  4. grzK plays an important role in CD8 (show CD8A Proteins)(+) T-cell cytotoxicity both in the presence and absence of grzA and B.

Human Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. Extracellular GrK (show GRK4 Proteins) is an unexpected direct modulator of lipopolysaccharide-TLR4 (show TLR4 Proteins) signaling during the antimicrobial innate immune response.

  2. Granzyme K plays an important physiological role in immunoregulation of adaptive immunity underlying the cytotoxicity of CD56 (show NCAM1 Proteins)(bright) natural killer (NK) cells toward activated T cells.

  3. Gr3 (show PRLHR Proteins) proenzymes is activated by cathepsin C (show CTSC Proteins) which concomitantly decreased the molecular weight to that of active Gr3 (show PRLHR Proteins).

  4. The present findings thus introduce the possibility that human beta-tryptase (show TPSAB1 Proteins), after mast cell degranulation and exposure to neutral pH in the tissue, may dissociate into active monomers with properties that are distinct from the tetrameric counterpart.

  5. We found human GzmK triggers rapid cell death independently of caspase (show CASP3 Proteins) activation. The features of death are characterized by rapid externalization of phosphatidylserine, nuclear morphological changes and single-stranded DNA nicks.

  6. GzmK-induced caspase (show CASP3 Proteins)-independent death occurs through Bid (show BID Proteins)-dependent mitochondrial damage that is different from GzmA (show GZMA Proteins)

  7. Rsults indicate that plasma levels of Granzyme K could serve as a useful diagnostic marker to stage sepsis, permitting better classification, specific treatments of patients, and may play a functional role in the development of sepsis.

  8. GrK (show GRK4 Proteins) not only constitutes a redundant functional backup mechanism that assists GrA (show NR3C1 Proteins)-induced cell death but that it also displays a unique function by cleaving its own specific substrates.

  9. p53 (show TP53 Proteins) is as a cytotoxic bomb that can be triggered by granzyme K, leading to potentiating killing efficacy.

Rabbit Granzyme K (Granzyme 3, Tryptase II) (GZMK) interaction partners

  1. Data show that the serum levels of mast cell tryptase, monocyte chemoattractant protein-1 (MCP-1 (show CCL2 Proteins)) and interleukin-8 (IL-8 (show IL8 Proteins)) decreased significantly in Dachengqi decoction treatment group.

Granzyme K (Granzyme 3, Tryptase II) (GZMK) Protein Profile

Protein Summary

This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Gene names and symbols associated with GZMK

  • granzyme K-like (LOC100052126)
  • granzyme K (Gzmk)
  • granzyme K (granzyme 3; tryptase II) (GZMK)
  • granzyme K (granzyme 3; tryptase II) (Gzmk)
  • granzyme K-like (LOC100345938)
  • TRYP2 protein

Protein level used designations for GZMK

NK-Tryp-2 , NK-tryptase-2 , RNK-Tryp-2 , fragmentin-3 , granzyme 3 , granzyme K , granzyme K (serine protease, granzyme 3; tryptase II) , granzyme-3 , tryptase II

GENE ID SPECIES
100052126 Equus caballus
14945 Mus musculus
29165 Rattus norvegicus
3003 Homo sapiens
100233185 Sus scrofa
426168 Gallus gallus
100727863 Cavia porcellus
100345938 Oryctolagus cuniculus
Selected quality suppliers for Granzyme K (Granzyme 3, Tryptase II) Proteins (GZMK)
Did you look for something else?