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anti-Growth Differentiation Factor 11 (GDF11) Antibodies

The protein encoded by GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Additionally we are shipping GDF11 Kits (55) and GDF11 Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GDF11 10220 O95390
GDF11 14561 Q9Z1W4
GDF11 29454  
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Top anti-GDF11 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with GDF11 antibody (N-term) (ABIN388814), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of GDF11 (arrow) using rabbit polyclonal GDF11 Antibody (R47) (ABIN388814).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the GDF11 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit PE IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IHC (p), ELISA Immunoperoxidase of monoclonal antibody to GDF11 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB GDF11 monoclonal antibody (M06), clone 4F7 Western Blot analysis of GDF11 expression in K-562 . Detection limit for recombinant GST tagged GDF11 is approximately 1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details

GDF11 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GDF11 Antibodies

  1. Human Polyclonal GDF11 Primary Antibody for EIA, WB - ABIN357455 : Lee, McPherron: Myostatin and the control of skeletal muscle mass. in Current opinion in genetics & development 1999 (PubMed)
    Show all 3 references for ABIN357455

  2. Human Polyclonal GDF11 Primary Antibody for IHC (p), WB - ABIN388814 : Gamer, Wolfman, Celeste, Hattersley, Hewick, Rosen: A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos. in Developmental biology 1999 (PubMed)
    Show all 2 references for ABIN388814

More Antibodies against GDF11 Interaction Partners

Zebrafish Growth Differentiation Factor 11 (GDF11) interaction partners

  1. First non-mammalian growth/differentiation factor (GDF) 11-like homolog was cloned from zebrafish. Sequencing,phylogenetic analysis,tissue expression, and mRNA levels during embryonic development are reported.

Human Growth Differentiation Factor 11 (GDF11) interaction partners

  1. GDF11 is essential for mammalian development and has been suggested to regulate aging of multiple tissues. It functions in the heart, skeletal muscle, and brain. Review.

  2. GDF11 inhibits rather than helps muscle regeneration.

  3. Show that there is no age-related cardiac hypertrophy in disease-free 24-month-old C57BL/6 mice and that restoring GDF11 in old mice has no effect on cardiac structure or function.

  4. in vitro sprout formation was increased as well by GDF11 treatment

  5. Suggest GDF11 functions as encephalic regionalizing factor in neural differentiated mouse embryonic stem cells.

  6. GDF11 is a critical rheostat for bone turnover and a key integrator of bone homeostasis.

  7. These data demonstrate GDF11 to be a master regulator of neural stem cell transcription that can suppress cell proliferation and migration by regulating the expression of numerous genes involved in both these processes

  8. Expression of GDF11, a cytokine which blocks terminal erythroid maturation, was increased in erthyroblasts of thalassemic patients.

  9. Quantitative real-time reverse transcription-PCR in colorectal cancer specimens obtained from 130 patients showed that GDF11 mRNA expression in cancer tissue was significantly higher than in normal tissue

  10. Members of the transforming growth factor beta (TGFbeta (show TGFB1 Antibodies)) superfamily, bone morphogenetic protein 2 (BMP2 (show BMP2 Antibodies)), and growth and differentiation factor 11 (GDF11), can signal cultured RGCs to form dendrites.

Mouse (Murine) Growth Differentiation Factor 11 (GDF11) interaction partners

  1. Circulating levels of GDF11/8 declines with age in mice (and sheep, horses and rats).

  2. Data show that circulating myostatin (show MSTN Antibodies) levels decreased with age and estimates of growth differentiation factor 11 (GDF11) levels using myostatin (show MSTN Antibodies) null mice indicate that they were almost 500 times lower than those for myostatin (show MSTN Antibodies).

  3. Two new studies demonstrate that GDF11 this "factor of youth" rejuvenates stem cells found in the skeletal muscle and brain of aged mice.

  4. Therefore, we postulate that GDF (show GDF5 Antibodies)-11DeltaEx1 may act as a long non-coding RNA to regulate the transcription of canonical GDF-11 and/or other genes in skeletal muscle and other tissues

  5. Expression of GDF11, a cytokine which blocks terminal erythroid maturation, was increased in erthyroblasts of thalassemic mice.

  6. GDF11 inhibited erythroid maturation in mice in vivo and ex vivo. Expression of GDF11 in erythroid precursors decreased progressively with maturation, suggesting an inhibitory role for GDF11 in late-stage erythroid differentiation.

  7. Gdf11 stimulates expression of a Hoxd11 (show HOXD11 Antibodies)/lacZ (show GLB1 Antibodies) transgene in the mouse embryo tailbud.

  8. GASP-1 (show GPRASP1 Antibodies) and GASP-2 (show WFIKKN1 Antibodies) are important modulators of GDF-11 and MSTN (show MSTN Antibodies) activity in vivo.

  9. Gdf11 signaling is a major coordinator of the trunk-to-tail transition during mouse development

  10. Using modified aptamer-based proteomics, study identified the TGF-beta (show TGFB1 Antibodies) superfamily member GDF11 as a circulating factor in young mice that declines with age.

GDF11 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Gene names and symbols associated with GDF11

  • growth differentiation factor 11 (Gdf11) antibody
  • growth differentiation factor 11 (gdf11) antibody
  • growth differentiation factor 11 (GDF11) antibody
  • growth differentiation factor 11 (LOC100341680) antibody
  • BMP-11 antibody
  • Bmp11 antibody
  • GDF11 antibody

Protein level used designations for GDF11

growth/differentiation factor 11 , growth differentiation factor 11 , GDF-11 , bone morphogenetic protein 11

GENE ID SPECIES
100858318 Cavia porcellus
406247 Danio rerio
451970 Pan troglodytes
10220 Homo sapiens
14561 Mus musculus
29454 Rattus norvegicus
100341680 Oryctolagus cuniculus
100722750 Cavia porcellus
397254 Sus scrofa
606826 Canis lupus familiaris
540517 Bos taurus
101104900 Ovis aries
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