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helix-loop-helix (HLH) protein\; may function as repressor in neurons [RGD, Feb 2006].. Additionally we are shipping HES3 Antibodies (16) and many more products for this protein.
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The STAT3 (show STAT3 Proteins)-Ser (show SIGLEC1 Proteins)/Hes3 Signaling Axis was first identified as a major regulator of neural stem cells and, subsequently, cancer stem cells
Data show that transcription factor Hes3 is expressed in adult pancreatic islets and dissociated cultures of pancreatic islet cells.
expression of the transcription factor Hes3 in the mouse and human ocular surface, and in pterygium
Hes3 is expressed in cultures from glioblastoma multiforme which express neural stem cell markers
CXorf6 (show MAMLD1 Proteins) transactivates the Hes3 promoter, augments testosterone production
Hes3 expression is reduced at peak demyelination and is partially restored within 1 week after cuprizone withdrawal. This raises the possibility of Hes3 involvement in demyelination/remyelination.
Mamld1 (show MAMLD1 Proteins) enhances Cyp17a1 (show CYP17A1 Proteins) expression primarily in Leydig cells and permit to produce a sufficient amount of testosterone for male sex development, independently of the Hes3-related non-canonical Notch (show NOTCH1 Proteins) signaling
inactivation of Hes1 and Hes5 (show HES5 Proteins), known Notch (show NOTCH1 Proteins) effectors, and additional inactivation of Hes3 extensively accelerate cell differentiation and cause a wide range of defects in brain formation
helix-loop-helix (HLH) protein\; may function as repressor in neurons
hairy and enhancer of split 3
, class B basic helix-loop-helix protein 43
, transcription factor HES-3