You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) Antibodies

HRK encodes a member of the BCL-2 protein family. Additionally we are shipping HRK Kits (7) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HRK 8739 O00198
HRK 12123 P62816
HRK 117271 P62817
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-HRK Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of Hrk in mouse pancreas tissue lysate with AP30395PU-N Hrk antibody at (A) 2.5 and (B) 5 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 6 to 8 Days
$286.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Hrk-BH3 (ABIN388104) western blot analysis in mouse kidney tissue lysates (35 µg/lane).This demonstrates the Hrk antibody detected the Hrk protein (arrow). Hrk BH3 Domain Antibody (ABIN388104)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p) Formalin-fixed and paraffin embedded rat brain tissue labeled with Rabbit Anti-Hrk Polyclonal Antibody, Unconjugated (ABIN2559409) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB   0.1 mg Log in to see 6 to 8 Days
$445.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 3 to 4 Days
$213.53
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 8 to 10 Days
$727.83
Details

HRK Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine) , ,


,
Rat (Rattus) , ,


,

Top referenced anti-HRK Antibodies

  1. Human Polyclonal HRK Primary Antibody for WB - ABIN2474088 : Giroud, Bernard, Guignier, Gras, Bonaiti, Dumas: [Lack of genetic link between the HLA system and idiopathic generalized epilepsy]. in Presse médicale (Paris, France : 1983) 1991 (PubMed)
    Show all 4 references for ABIN2474088

  2. Human Polyclonal HRK Primary Antibody for ELISA, WB - ABIN1002403 : Lockshin, Osborne, Zakeri: Cell death in the third millennium. in Cell death and differentiation 2000 (PubMed)
    Show all 3 references for ABIN1002403

  3. Human Polyclonal HRK Primary Antibody for WB - ABIN318751 : Nakamura, Ishida, Shimada, Nakase, Sakaki, Konishi: Frequent HRK inactivation associated with low apoptotic index in secondary glioblastomas. in Acta neuropathologica 2005 (PubMed)

More Antibodies against HRK Interaction Partners

Human Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) interaction partners

  1. our findings suggest that induction of the BH3-only (show BBC3 Antibodies) protein Hrk is a critical step in 2-ME activation of the JNK (show MAPK8 Antibodies)-induced apoptotic pathway, targeting mitochondria by liberating proapoptotic protein Bak (show BAK1 Antibodies).

  2. SUZ12 (show SUZ12 Antibodies) promotes the proliferation of human EOC cells by inhibiting apoptosis and HRK is a novel SUZ12 (show SUZ12 Antibodies) target gene whose upregulation contributes to apoptosis induced by SUZ12 (show SUZ12 Antibodies) knockdown.

  3. Diva (show BCL2L10 Antibodies) binds peptides derived from the BH3 domain of several other proapoptotic Bcl-2 (show BCL2 Antibodies) proteins, including mouse Harakiri, Bid (show BID Antibodies), Bak (show BAK1 Antibodies) and Bmf (show BMF Antibodies).

  4. The BH3-only (show BBC3 Antibodies) protein harakiri (HRK) is transactivated by ATF4 (show ATF4 Antibodies) in severe hypoxia through direct binding of ATF4 (show ATF4 Antibodies) to the promoter region.

  5. Data suggest that DP5 and PUMA/BBC3 (p53 up-regulated modulator of apoptosis (show BBC3 Antibodies)/bcl-2-binding component 3 (show BBC3 Antibodies)) contribute to palmitate-induced apoptosis of pancreatic beta-cells via lipotoxic endoplasmic reticulum stress.

  6. These results are used to propose a tentative structural model of how Harakiri works.

  7. analysis of a novel interaction between Bcl-2 (show BCL2 Antibodies) members Diva (show BCL2L10 Antibodies) and Harakiri

  8. Hrk is involved in the induction of apoptosis in RGCs after optic nerve transection.

  9. apoptosis inducers as diverse as oncoprotein inhibitors and cell death receptor activators trigger Hrk expression via blockade of DREAM in leukemia cells

  10. Data report that human oocytes and fragmenting preimplantation embryos possess transcripts encoding Harakiri and caspase-3 (show CASP3 Antibodies).

Mouse (Murine) Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK) interaction partners

  1. Hrk deficiency does not significantly attenuate the widespread apoptosis seen in the Bcl-x (show BCL2L1 Antibodies) (-/-) embryonic nervous system, indicating that other BH3-only (show BBC3 Antibodies) molecules, alone or in combination, may regulate BAX (show BAX Antibodies) activation in immature neurons.

  2. DP5 plays an important role in neuronal cell death induced by axotomy and NGF (show NGFB Antibodies) deprivation through the regulation of mitochondrial function and caspase-3 (show CASP3 Antibodies) activation

  3. These results demonstrate that HRK contributes to apoptosis signalling elicited by trophic factor withdrawal in certain neuronal populations but is dispensable for apoptosis of haematopoietic cells.

  4. in response to PAHs, Ahr (show AHR Antibodies)-mediated activation of the harakiri, BCL2 interacting protein (contains only BH3 domain), was necessary for execution of cell death.

  5. The effect of antisense oligonucleoties specific to the harakiri mRNA on spontaneous and induced defects of mouse preimplantation embryo development

HRK Antigen Profile

Protein Summary

This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with HRK

  • harakiri, BCL2 interacting protein (contains only BH3 domain) (HRK) antibody
  • harakiri, BCL2 interacting protein (contains only BH3 domain) (Hrk) antibody
  • AI838259 antibody
  • Bid3 antibody
  • Dp5 antibody
  • harakiri antibody

Protein level used designations for HRK

BCL2-interacting protein , BH3-interacting domain-containing protein 3 , activator of apoptosis Hrk , activator of apoptosis harakiri , death protein 5 , neuronal death protein DP5 , BH3 interacting (with BCL2 family) domain, apoptosis agonist , BH3 interacting domain 3

GENE ID SPECIES
8739 Homo sapiens
12123 Mus musculus
117271 Rattus norvegicus
Selected quality suppliers for anti-HRK (HRK) Antibodies
Did you look for something else?