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heat shock protein that binds alpha-filamin [RGD, Feb 2006].. Additionally we are shipping HSPB7 Antibodies (64) and HSPB7 Kits (7) and many more products for this protein.
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Human HSPB7 Protein expressed in Escherichia coli (E. coli) - ABIN667773
Matkovich, Van Booven, Hindes, Kang, Druley, Vallania, Mitra, Reilly, Cappola, Dorn: Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease. in The Journal of clinical investigation 2010
Show all 2 references for ABIN667773
HSPB7 loci is associated in the pathophysiologuy of ischemic heart failure.
Results imply that HSBP7 is likely to be a tumor suppressor gene regulated by p53 (show TP53 Proteins) and its downregulation by hypermethylation may play a critical role in renal carcinogenesis.
HSPB7 is a potential early biomarker after MI and serves as an independent risk factor of ACS in patients with acute chest pain.
Overexpression of HSPB1 (show HSPB1 Proteins), as well as HSPB6 (show HSPB6 Proteins), HSPB7 and HSPB8 (show HSPB8 Proteins) independently protect against tachycardia remodeling by attenuation of the RhoA GTPase pathway at different levels.
Data show a significant association between a SNP in HSPB7 gene (rs1739843, minor allele frequency 39%) and idiopathic DCM.
The rs1738943 shows that although this SNP is located within HSPB7, it resides in a block of high LD that spans HSPB7 and a nearby gene, CLCNKA (show CLCNKA Proteins), which encodes a voltage-sensitive chloride channel (show CLCA1 Proteins) expressed mainly in the kidney.
Cardiac signaling genes exhibit unexpected sequence diversity in sporadic cardiomyopathy, revealing HSPB7 polymorphisms associated with disease.
HSPB7 constitutively localized to SC35 (show SRSF2 Proteins) splicing speckles, driven by its N-terminus. Unlike HSPB1 (show HSPB1 Proteins) and HSPB5 (show CRYAB Proteins), that chaperoned heat unfolded substrates and kept them folding competent, HSPB7 did not support refolding.
These results imply that HspB2 (show HSPB2 Proteins) and HspB7 might be up-regulated by ethanol during the short-term differentiation of neural stem cells.
heat shock protein that binds alpha-filamin
cardiovascular heat shock protein
, heat shock 27kDa protein family, member 7 (cardiovascular)
, heat shock 27kD protein family, member 7 (cardiovascular)
, heat shock protein beta-7
, heat shock protein 25 kDa 2 (cardiovascular)
, protein p19/6.8
, heat shock 27kD protein family member 7