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beta-globin chain of hemoglobin, which binds and transports oxygen to peripheral tissues [RGD, Feb 2006].. Additionally we are shipping HBB Antibodies (43) and HBB Kits (9) and many more products for this protein.
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The study analyzed protein-DNA interactions in the murine beta-globin gene locus.
Data suggest that beta-globin promoters in general do not exert any appreciable nonlocal effects on chromatin structure.
HIRA (show HIRA Proteins) is not only critical for beta-globin expression but is also required for activation of the erythropoietic regulators EKLF (show KLF1 Proteins) and GATA binding protein 1 (GATA1).
Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.
A single observed change in a histocompatibility complex (MHC) peptide (I-Ek) anchor residue historically induces a different topology at an important segment of hemoglobin beta chain peptide bound to a T-cell receptor amino acid residue.
GATA-1 occupies the beta-major globin promoter normally in fetal liver erythroblasts from mice lacking the LCR, suggesting that GATA-1 binding to the promoter and LCR are independent events that occur prior to loop formation.
These results are consistent with the hypothesis that activation of the beta-globin gene locus is initiated by protein complexes recruited to the LCR.
Reactive beta globin sulfhydryl group concentration is genetically determined.
an Oct-1 (show POU2F1 Proteins) binding site and an enhancer in the intron cooperate to increase expression levels from LCR (show CBR2 Proteins) beta-globin genes
beta-globin chain of hemoglobin, which binds and transports oxygen to peripheral tissues
III beta-1 globin
, III beta-2 globin
, hemoglobin beta chain complex
, hemoglobin beta chain, major-form
, hemoglobin beta-1 chain
, hemoglobin subunit beta-1