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HMGB3 belongs to the high mobility group (HMG) protein superfamily. Additionally we are shipping High Mobility Group Box 3 Antibodies (80) and High Mobility Group Box 3 Kits (9) and many more products for this protein.
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HMGB3 regulates the genes expression of WNT (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) pathway
Therefore, we infer that HMGB3 is a functional target of miR (show MLXIP Proteins)-27b in modulation of tamoxifen resistance and EMT (show ITK Proteins).
our data suggests HMGB3 may serve as an important oncoprotein and indicate that overexpression of HMGB3 in urinary bladder cancer could be used as a potential prognostic marker.
High expression of HMGB3 is associated with lymph node metastases in gastric cancer.
In this family, microphthalmia, microcephaly, intellectual disability, and short stature are associated with a mutation on the X chromosome in the HMGB3 gene.
regulation of HMGB3 by miR (show MLXIP Proteins)-205 reduced both proliferation and invasion of breast cancer cells.
Association between co-expression networks involving HMGB3 and differentially-expressed genes in gastric cancer.
HMGB3 has a role in gastric cancer disease onset and progression by regulating the cell cycle
HMGB3 plays an important role in non-small cell lung cancer progression.
Data indicate that myomiR-206 modulates Hmgb3 expression during myogenesis.
Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group (show SSRP1 Proteins) A2 during epithelial-to-mesenchymal transition.
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of mixed growth hormone (show GH1 Proteins)/prolactin (show PRL Proteins) cell pituitary adenomas.
Hmgb3 deficiency leads to a failure of hematopoietic stem cells to expand into normal numbers of lymphoid progenitor and myeloid progenitors
Hmgb3 is required for the proper balance between hematopoietic stem cell self-renewal and differentiation.
Xhmgb3 is required for cell proliferation of the eye and brain as a downstream target of Xenopus rax/Rx1 (show RAX Proteins).
HMGB3 expression is under complex transcriptional and post-transcriptional control by alternate promoter usage, alternative splicing mechanism and microRNAs in dairy cattle.
results show that, in contrast to other Arabidopsis HMGB proteins such as HMGB1 and HMGB5, the HMGB2/3 and HMGB4 proteins occur preferentially in the cell nucleus, but to various extents also in the cytoplasm
HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997
high mobility group protein 2a
, high mobility group protein 4
, high mobility group protein B3
, high-mobility group (nonhistone chromosomal) protein 4
, high-mobility group box 3
, non-histone chromosomal protein
, high mobilty group protein 2A
, high-mobility group protein 4
, high mobility group box 3
, HMGB3 transcript variant 1/2
, high mobility group B3b protein
, high mobility group protein
, High mobility group protein B3
, high mobility group protein 1
, high mobility group protein B1