anti-Histamine Receptor H4 (HRH4) Antibodies

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Additionally we are shipping Histamine Receptor H4 Kits (23) and Histamine Receptor H4 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HRH4 59340 Q9H3N8
HRH4 170704 Q91ZY1
HRH4 225192 Q91ZY2
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Top anti-Histamine Receptor H4 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, WB Western blot analysis of human chronic myelogenous leukemia (K562) (lanes 1 and 3) and human promyelocytic leukemia (HL-60) (lanes 2 and 4) cell lysates: 1, 2. Anti-Human H4 Histamine Receptor (extracellular) antibody, (1:400). 3, 4. Anti-Human H4 Histamine Receptor (extracellular) antibody, preincubated with the control peptide antigen. Indirect flow cytometry analysis of H4 Histamine Receptor expression in live intact Jurkat (acute T-cell leukemia) cell lines Black: Unstained cells + goat-anti-rabbit-PE. Green: Cells+ Anti-Human H4 Histamine Receptor (extracellular) antibody, (1:20) + goat-anti-rabbit-PE. 50 μL Log in to see 10 to 11 Days
$678.57
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HRH4 Antibody Titration: 1.0 ug/ml Positive Control: 721_B Whole Cell HRH4 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB Mouse brain lysates probed with Anti-HRH4 Polyclonal Antibody, Unconjugated  at 1:300 in 4˚C. Followed by conjugation to secondary antibody -HRP) at 1:5000 90min in 37˚C. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of LOVO cells, using HRH4 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IF, WB 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated WB HRH4 Antibody (Center)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the HRH4 antibody detected the HRH4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Histamine H4 Receptor antibody detects Histamine H4 Receptor protein by western blot analysis. A. 30 μg Jurkat whole cell lysate/extract B. 30 μg Raji whole cell lysate/extract C. 30 μg NCI-H929 whole cell lysate/extract 10 % SDS-PAGE Histamine H4 Receptor antibody , dilution: 1:500 WB Image Histamine H4 Receptor antibody detects Histamine H4 Receptor protein by western blot analysis. A. 30 μg HeLa whole cell lysate/extract B. 30 μg whole cell lysate/extract of HRH4 shRNA-transfected HeLa cells 10 % SDS-PAGE Histamine H4 Receptor antibody , dilution: 1:500 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p) Cells expressing target protein - immunostained with target antibody 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemistry-Paraffin: Histamine H4 R Antibody [NLS3775] - IHC analysis of Lymph node using this antibody at 12 ug/ ml. 0.05 mL Log in to see 7 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details

HRH4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


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Mouse (Murine)


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Top referenced anti-Histamine Receptor H4 Antibodies

  1. Human Polyclonal HRH4 Primary Antibody for IF, WB - ABIN1742054 : Pokkali, Das, R: Expression of CXC and CC type of chemokines and its receptors in tuberculous and non-tuberculous effusions. in Cytokine 2008 (PubMed)

More Antibodies against Histamine Receptor H4 Interaction Partners

Guinea Pig Histamine Receptor H4 (HRH4) interaction partners

Human Histamine Receptor H4 (HRH4) interaction partners

  1. Histamine H4 receptors could not be identified in five experimental models of the guinea-pig that are suited for the detection of presynaptic inhibitory receptors (hippocampus aorta, atrium, renal cortex and vas (show AVP Antibodies) deferens) whereas H3 receptors could be shown in the peripheral tissues but not in the hippocampus

  2. Taken together these data demonstrate that compound A and compound L may block H4R-mediated downstream signaling events.

  3. We also found that the activation of H4R caused the release of IL-13 (show IL13 Antibodies) and RANTES (show CCL5 Antibodies) on human mast cells.these data demonstrate that the H4R activates divergent signaling pathways to induce cytokine and chemokine (show CCL1 Antibodies) production in human mast cells

  4. H4R may be involved in the maintenance of healthy oral mucosa. In oral lichen planus, this maintenance might be impaired by mast cell degranulation and inflammatory cytokines.

  5. Activation of the H4R could induce phosphorylation of ERK (show EPHB2 Antibodies).

  6. Suggest roles for HRH4 polymorphisms and ankylosing spondylitis susceptibility.

  7. Molecular modelling studies, including molecular dynamic simulations and calculation of Gibbs energy of solvation of hH3R (show HRH3 Antibodies) and hH4R, were studied.

  8. HRH4 was increased in clinically-isolated syndrome and different stages of multiple sclerosis compared to health control.

  9. No evidence was found for the presence of histamine H4 receptor in monocytes.

  10. In neutrophils, the H4 receptor may block signals emanating from Mac-1 (show ITGAM Antibodies)-controlling degranulation. Engagement of the H4 receptor by selective agonists blocked Mac-1 (show ITGAM Antibodies)-dependent activation of p38 MAPK (show MAPK14 Antibodies).

Mouse (Murine) Histamine Receptor H4 (HRH4) interaction partners

  1. Results illustrate that histamine H4 receptors (H4R) modulates various neurophysiological functions such as locomotor activity, anxiety, nociception and feeding behaviour, confirming the importance of the integrity and functionality of neuronal H4R in the histaminergic regulation of neuronal functions.

  2. These results identify the H4R as a new target controlling NK cell migration and NK cell-dendritic cell interaction in the skin during early allergic inflammation. These results further suggest that blocking the H4R in the skin might be beneficial in diseases like atopic dermatitis.

  3. Histamine H4 receptor knockout mice display reduced inflammation in a chronic model of atopic dermatitis

  4. These results indicate a proinflammatory role of histamine via H4R in inflammatory bowel disease.

  5. The histamine H4 receptor mediates inflammation and Th17 responses in preclinical models of arthritis.

  6. H4R expression on murine keratinocytes was detected after stimulation with LPS (show TLR4 Antibodies) and peptidoglycan.

  7. the present study shows that H4 receptors potentially play a role in IgE induced FcepsilonRI (show FCER1A Antibodies) upregulation

  8. Acting via its H4 receptors, histamine impedes lipopolysaccharide-induced microglia migration and interleukin (IL)-1beta (show IL1B Antibodies) release under inflammatory challenge.

  9. development of allergic rhinitis proceeded in two distinct stages: histamine release from FcepsilonRI (show FCER1A Antibodies)-activated mast cells, followed by histamine-mediated recruitment of H(4)R-expressing basophils to the nasal cavity and activation through FcepsilonRI (show FCER1A Antibodies).

  10. The majority of hypertrophic ATDC5 chondrocytes express H4R, suggesting that this receptor is associated with the differentiation of chondrocytes into hypertrophic cells.

Histamine Receptor H4 (HRH4) Antigen Profile

Protein Summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HRH4

  • histamine receptor H4 (HRH4) antibody
  • histamine H4 receptor (LOC100358525) antibody
  • histamine receptor H4 (Hrh4) antibody
  • AXOR35 antibody
  • BG26 antibody
  • GPCR105 antibody
  • GPRv53 antibody
  • H4 antibody
  • H4R antibody
  • HH4R antibody
  • HRH4 antibody

Protein level used designations for HRH4

histamine H4 receptor , histamine receptor H4 , histamine 4 receptor , histamine H4 receptor-like , G-protein coupled receptor 105 , SP9144 , pfi-013 , H4R , HH4R

GENE ID SPECIES
397224 Sus scrofa
468501 Pan troglodytes
490512 Canis lupus familiaris
702044 Macaca mulatta
769106 Gallus gallus
783312 Bos taurus
783354 Bos taurus
100034111 Equus caballus
100358525 Oryctolagus cuniculus
100379272 Cavia porcellus
100442858 Pongo abelii
59340 Homo sapiens
170704 Rattus norvegicus
225192 Mus musculus
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