anti-Histidine Decarboxylase (HDC) Antibodies

HDC encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Additionally we are shipping Histidine Decarboxylase Proteins (18) and Histidine Decarboxylase Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HDC 380629  
HDC 3067 P19113
HDC 24443  
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Top anti-Histidine Decarboxylase Antibodies at

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC (p), WB Anti-Histidine decarboxylase antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate Anti-Histidine decarboxylase antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB HDC Antibody (N-term) (ABIN658095) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the HDC antibody detected the HDC protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated WB Western blot analysis of HDC expression in rat fetal liver tissue lysate. 100 μg Log in to see 2 to 3 Days
Human Rabbit Un-conjugated ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Human Brain, antibody was diluted at 1:100. 100 μL Log in to see 16 Days
Dog Rabbit Un-conjugated IHC (fro), IF, IHC (p), WB   50 μL Log in to see 6 to 8 Days
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat lung using HDC antibody at dilution of 1:200 (400x lens). 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB L1 mouse stomach lysates L2 mouse liver lysates probed with Anti HDC Polyclonal Antibody, Unconjugated (ABIN736986) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 73kD. Observed band size: 73kD 100 μL Log in to see 3 to 7 Days
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
Cow Goat Un-conjugated ELISA, WB ABIN4902656 (0.03µg/ml) staining of Human Cerebellum lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μL Log in to see 16 Days

HDC Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,

Human , ,

, , , , ,
Rat (Rattus) , ,


Top referenced anti-Histidine Decarboxylase Antibodies

  1. Dog (Canine) Polyclonal HDC Primary Antibody for IHC (fro), IF - ABIN115730 : Dartsch, Persson: Recombinant expression of rat histidine decarboxylase: generation of antibodies useful for western blot analysis. in The international journal of biochemistry & cell biology 1998 (PubMed)
    Show all 4 Pubmed References

More Antibodies against Histidine Decarboxylase Interaction Partners

Fruit Fly (Drosophila melanogaster) Histidine Decarboxylase (HDC) interaction partners

  1. genes encoding for proteins involved in histamine signaling [histidine decarboxylase (hdc), histamine-gated chloride channel (show CLCA1 Antibodies) subunit 1 (hisCl1), ora (show RHO Antibodies) transientless (ort)] cause abnormal temperature preferences

Zebrafish Histidine Decarboxylase (HDC) interaction partners

  1. Ethanol upregulates histidine decarboxylase expression in neural brain networks.

Mouse (Murine) Histidine Decarboxylase (HDC) interaction partners

  1. The H3 receptor is upregulated in the striatum in the Hdc KO mouse model of tic disorders.

  2. Lack of endogenous histamine in NOD HDC(-/-) mice decreased the incidence of diabetes in relation to their wild-type counterpart.

  3. the structure and function of the retina in mice that lacked expression of the rate limiting enzyme in the formation of histamine, histidine decarboxylase (Hdc-/- mouse), were investigated.

  4. SDS (show SDS Antibodies) induces itch through increased production of epidermal histamine, which results from an increase in the gene expression and post-translation processing of L-histidine decarboxylase.

  5. HDC, whose expression is remarkably downregulated during the first few days after birth in dermal cells of mice, plays essential roles in the hair-inducing ability of newborn mouse dermal cells

  6. An increased expression of H3 receptors in HDC KO mice without any changes in the spontaneous firing of "histaminergic" neurons without histamine and their responses to the H3 receptor agonist (R)-alpha-methylhistamine.

  7. Histidine decarboxylase was found at comparably high levels in mouse striatum.

  8. There was no difference in the levels of vascular endothelial growth factor between HDC-/- or wild-type mice, either in the lung or in bronchoalveolar-lavage cells.

  9. HDC-/- mice showed reduced severity of K/BxN serum-induced arthritis.

  10. in 12 day old embryonic stem cells histidine decarboxylase was confined to peripheral cells and small clusters of cells, inner cells were usually negative for it

Human Histidine Decarboxylase (HDC) interaction partners

  1. Human histidine decarboxylase (HDC) and dopa decarboxilase (DDC (show DDC Antibodies)) are highly homologous enzymes responsible for the synthesis of biogenic amines (BA) like histamine, and serotonin and dopamine, respectively. This review summarizes the analogies and differences in their origin as well as their common pathophysiological scenarios. [review]

  2. a Possible Role for the Histidine Decarboxylase Gene in Tourette Syndrome in the Chinese Han Population

  3. Human enterochromaffin-like cells appear to partially co-express VMAT-2 and HDC. Co-expression of VMAT-2 and HDC might be required for increased histamine production in patients with gastric neuroendocrine tumors.

  4. The findings indicate that polymorphisms of HDC gene were significantly associated with breast cancer in Chinese Han population and may be novel diagnostic or therapeutic targets for breast cancer.

  5. HDC rs17740607 polymorphism is at least a partial loss-of-function variant and acts as a protective factor against chronic heart failure

  6. Investigated variation across the HDC (histidine decarboxylase) gene for association with Tourette Syndrome.

  7. HDC production in the stomach is associated with bile acid exposure and its related transcriptional regulation network of FXR (show NR1H4 Antibodies), SHP (show LAMC1 Antibodies), and CDX1 (show CDX1 Antibodies).

  8. Data indicate that histidine decarboxylase (HDC) is expressed by neutrophils.

  9. Structural study reveals that Ser (show SIGLEC1 Antibodies)-354 determines substrate specificity on human histidine decarboxylase.

  10. crystal of histidine decarboxylase belonged to space group C2, with unit-cell parameters a = 215.16, b = 112.72, c = 171.39 A, beta = 110.3 degrees

Histidine Decarboxylase (HDC) Antigen Profile

Protein Summary

This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.

Gene names and symbols associated with HDC

  • Histidine decarboxylase (Hdc) antibody
  • histidine decarboxylase (HDC) antibody
  • histidine decarboxylase (LOC548615) antibody
  • histidine decarboxylase (hdc) antibody
  • histidine decarboxylase (Desac_2880) antibody
  • histidine decarboxylase (LOC100313635) antibody
  • histidine decarboxylase (LOC100533309) antibody
  • hdc homolog, cell cycle regulator (Heca) antibody
  • histidine decarboxylase (Hdc) antibody
  • 4732480P20 antibody
  • anon-WO0140519.259 antibody
  • AW108189 antibody
  • CG3454 antibody
  • Dmel\\CG3454 antibody
  • Gm869 antibody
  • HDC antibody
  • Hdc-a antibody
  • Hdc-c antibody
  • Hdc-e antibody
  • Hdc-s antibody
  • HDCL antibody
  • JK910 antibody
  • LOC100313635 antibody

Protein level used designations for HDC

CG3454-PA , CG3454-PB , CG3454-PC , Hdc-PA , Hdc-PB , Hdc-PC , histidine decarboxylase , histidine-decarboxylase , histidine decarboxylase-like , headcase protein homolog , L-histidine decarboxylase

36076 Drosophila melanogaster
453425 Pan troglodytes
548615 Strongylocentrotus purpuratus
715287 Macaca mulatta
793609 Danio rerio
10438116 Desulfobacca acetoxidans DSM 11109
100313635 Saccoglossus kowalevskii
100407107 Callithrix jacchus
100435706 Pongo abelii
100533309 Aplysia californica
100583943 Nomascus leucogenys
380629 Mus musculus
3067 Homo sapiens
487551 Canis lupus familiaris
15186 Mus musculus
24443 Rattus norvegicus
100719978 Cavia porcellus
415454 Gallus gallus
100156724 Sus scrofa
515950 Bos taurus
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