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Hydroxyacyl-CoA Dehydrogenase Proteins (HADH)

HADH is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. Additionally we are shipping HADH Antibodies (129) and HADH Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HADH 3033 Q16836
HADH 113965 Q9WVK7
HADH 15107 Q61425
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Top HADH Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$286.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,803.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,803.17
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$2,524.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$322.14
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

HADH Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Mouse (Murine)

Top referenced HADH Proteins

  1. Human HADH Protein expressed in Escherichia coli (E. coli) - ABIN666958 : Tieu, Perier, Vila, Caspersen, Zhang, Teismann, Jackson-Lewis, Stern, Yan, Przedborski: L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease. in Annals of neurology 2004 (PubMed)
    Show all 2 references for ABIN666958

More Proteins for Hydroxyacyl-CoA Dehydrogenase (HADH) Interaction Partners

Human Hydroxyacyl-CoA Dehydrogenase (HADH) interaction partners

  1. We present clinical and laboratory findings together with the long-term clinical course of a case with a deep intronic HADH (show HADHA Proteins) splicing mutation (c.636+471G>T) causing neonatal-onset hyperinsulinemic hypoglycemia with mild progression

  2. in a cohort of hyperinsulinemic hypoglycemia patients from Isfahan, Iran, 78% were noted to have disease-causing mutations: 48% had HADH (show HADHA Proteins) mutations and 26% had ABCC8 (show ABCC8 Proteins) mutations.

  3. Next-generation sequencing reveals deep intronic cryptic ABCC8 (show ABCC8 Proteins) and HADH (show HADHA Proteins) splicing founder mutations causing hyperinsulinism by pseudoexon activation.

  4. Loss of function mutations in 3-Hydroxyacyl-CoA Dehydrogenase (HADH) cause leucine sensitive hyperinsulinaemic hypoglycaemia.

  5. Clinical, biochemical and molecular findings of four new Caucasian patients with HADH (show HADHA Proteins) deficiency.

  6. We recommend that HADH (show HADHA Proteins) sequence analysis is considered in all patients with diazoxide-responsive hyperinsulinemic hypoglycemia when recessive inheritance is suspected

  7. Congenital hyperinsulinism due to mutations in HNF4A (show HNF4A Proteins) and HADH (show HADHA Proteins).

  8. SCHAD (show HSD17B10 Proteins) deficiency can result in persistent hyperinsulinemic hypoglycemia of infancy

  9. Unlikely that variation in HADHSC plays a major role in the pathogenesis of type 2 diabetes in the examined cohorts.

  10. This case indicates that mutations of the HADH (show HADHA Proteins) gene should be sought in hyperinsulinemic patients in whom diffuse form of hyperinsulinemic hypoglycemia.

Mouse (Murine) Hydroxyacyl-CoA Dehydrogenase (HADH) interaction partners

  1. A physical association between short-chain 3-hydroxyacyl-coenzyme A dehydrogenase and important components of other key metabolic pathways. Most of the interactions were with enzymes in mitochondrial pathways.

  2. SCHAD (show HSD17B10 Proteins) is involved in thermogenesis, in the maintenance of body weight, and in the regulation of nutrient-stimulated insulin (show INS Proteins) secretion

  3. SCHAD (show HSD17B10 Proteins) deficiency causes hyperinsulinism by activation of GDH (show UGDH Proteins) via loss of inhibitory regulation of GDH (show UGDH Proteins) by SCHAD (show HSD17B10 Proteins).

  4. Results demonstrate that L-3-hydroxyacyl-CoA dehydrogenase type II (show HSD17B10 Proteins) (HADH (show HSD17B10 Proteins) II/ABAD (show HSD17B10 Proteins)) modulates 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity and suggests that mimetics may provide protective benefit in the treatment of Parkinson disease.

  5. SCHAD (show HSD17B10 Proteins) regulates insulin (show INS Proteins) secretion through a KATP channel-independent mechanism.

HADH Protein Profile

Protein Summary

This gene is a member of the 3-hydroxyacyl-CoA dehydrogenase gene family. The encoded protein functions in the mitochondrial matrix to catalyze the oxidation of straight-chain 3-hydroxyacyl-CoAs as part of the beta-oxidation pathway. Its enzymatic activity is highest with medium-chain-length fatty acids. Mutations in this gene cause one form of familial hyperinsulinemic hypoglycemia. The human genome contains a related pseudogene of this gene on chromosome 15.

Gene names and symbols associated with HADH

  • hydroxyacyl-CoA dehydrogenase (HADH)
  • hydroxyacyl-CoA dehydrogenase (hadh)
  • hydroxyacyl-Coenzyme A dehydrogenase pseudogene (HADH)
  • 3-hydroxyacyl-CoA dehydrogenase (short-chain) (Hadh)
  • 3-hydroxyacyl-CoA dehydrogenase (short-chain) (hadh)
  • Short chain 3-hydroxyacyl-CoA dehydrogenase (CNI02410)
  • short chain 3-hydroxyacyl-coa dehydrogenase (Tc00.1047053509717.90)
  • short chain 3-hydroxyacyl-coa dehydrogenase (Tc00.1047053510105.240)
  • short chain 3-hydroxyacyl-coa dehydrogenase (LmjF36.1140)
  • hydroxyacyl-CoA dehydrogenase (Hadh)
  • hydroxyacyl-Coenzyme A dehydrogenase (Hadh)
  • hydroxyacyl-Coenzyme A dehydrogenase (hadh)
  • AA409008 protein
  • AU019341 protein
  • AW742602 protein
  • HAD protein
  • HADH protein
  • HADH1 protein
  • Hadhsc protein
  • HCDH protein
  • HHF4 protein
  • MSCHAD protein
  • Schad protein
  • wu:fb66a11 protein
  • zgc:86777 protein

Protein level used designations for HADH

hydroxyacyl-Coenzyme A dehydrogenase , L-3-hydroxyacyl-Coenzyme A dehydrogenase , L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain , hydroxyacyl-coenzyme A dehydrogenase, mitochondrial , 3-hydroxyacyl-CoA dehydrogenase (short-chain) , Short chain 3-hydroxyacyl-CoA dehydrogenase , short chain 3-hydroxyacyl-coa dehydrogenase , medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase , short-chain 3-hydroxyacyl-CoA dehydrogenase , HCDH , hydroxylacyl-Coenzyme A dehydrogenase short chain , hydroxylacyl-Coenzyme A dehydrogenase, short chain , medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase , short chain 3-hydroxyacyl-CoA dehydrogenase , L-3-hydroxyacyl-CoA dehydrogenase , hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase

GENE ID SPECIES
461424 Pan troglodytes
496484 Xenopus (Silurana) tropicalis
613570 Bos taurus
696181 Macaca mulatta
5117561 Bradyrhizobium sp. ORS 278
5153095 Bradyrhizobium sp. BTAi1
3259805 Cryptococcus neoformans var. neoformans JEC21
3547310 Trypanosoma cruzi strain CL Brener
3552427 Trypanosoma cruzi strain CL Brener
5655364 Leishmania major strain Friedlin
3033 Homo sapiens
113965 Rattus norvegicus
380594 Xenopus laevis
420290 Gallus gallus
478506 Canis lupus familiaris
397604 Sus scrofa
532785 Bos taurus
15107 Mus musculus
445121 Danio rerio
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