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anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) Antibodies

HIF1AN encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HIF1AN 55662 Q9NWT6
HIF1AN 319594 Q8BLR9
HIF1AN 309434  
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Top anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor Antibodies at antibodies-online.com

Showing 10 out of 174 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-HIF1AN Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-HIF1AN  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-HIF1AN Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), IHC, WB 0.1 mL Log in to see 5 to 7 Days
$381.94
Details
Human Mouse Un-conjugated ICC, IF, IHC, WB FIH (fih162C), Mouse backskin. FIH Human Cell line mix 10ug 1 in 1000 WB 100 μg Log in to see 3 to 4 Days
$383.90
Details
Human Rabbit Un-conjugated EM, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Immunohistochemistry: Factor Inhibiting HIF-1 Antibody [ABIN151887SS] - Detection of FIH-1 in rat brain tissue, using ABIN151887 (1:100). Western Blot: Factor Inhibiting HIF-1 Antibody [ABIN151887SS] - Detection of FIH-1 in human samples, using ABIN151887 (1:500). 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-HIF1AN (C-term) Pab in A375 and mouse brain cell line lysate. HIF1AN (C-term)(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse HRP ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$422.40
Details
Human Mouse FITC ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$426.80
Details
Human Mouse Alkaline Phosphatase (AP) ICC, IF, IHC, WB   100 μg Log in to see 3 to 4 Days
$429.00
Details

HIF1AN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor Antibodies

  1. Human Polyclonal HIF1AN Primary Antibody for EM, ICC - ABIN151887 : Birle, Hedley: Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors. in Cancer research 2007 (PubMed)
    Show all 20 references for ABIN151887

  2. Human Monoclonal HIF1AN Primary Antibody for ICC, IF - ABIN440718 : Cockman, Lancaster, Stolze, Hewitson, McDonough, Coleman, Coles, Yu, Hay, Ley, Pugh, Oldham, Masson, Schofield, Ratcliffe: Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH). in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)
    Show all 7 references for ABIN440718

  3. Human Monoclonal HIF1AN Primary Antibody for ICC, IF - ABIN863094 : Soilleux, Turley, Tian, Pugh, Gatter, Harris: Use of novel monoclonal antibodies to determine the expression and distribution of the hypoxia regulatory factors PHD-1, PHD-2, PHD-3 and FIH in normal and neoplastic human tissues. in Histopathology 2005 (PubMed)
    Show all 3 references for ABIN863094

  4. Cow (Bovine) Polyclonal HIF1AN Primary Antibody for WB - ABIN2777654 : Linke, Stojkoski, Kewley, Booker, Whitelaw, Peet: Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor. in The Journal of biological chemistry 2004 (PubMed)

  5. Cow (Bovine) Polyclonal HIF1AN Primary Antibody for WB - ABIN2781044 : Jacobs, Hsing, Bain, Stevens, Wang, Chen, Chanock, Zheng, Xu, Thun, Calle, Rodriguez: Polymorphisms in angiogenesis-related genes and prostate cancer. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008 (PubMed)

More Antibodies against Hypoxia Inducible Factor 1, alpha Subunit Inhibitor Interaction Partners

Xenopus laevis Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) interaction partners

Human Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) interaction partners

  1. None of the clinicopathological parameters were associated with the expressions of FIH-1 and SOCS3 (show SOCS3 Antibodies) at mRNA level.

  2. This study provides novel clues indicating that miR (show MLXIP Antibodies)-21, miR (show MLXIP Antibodies)-31, and miR (show MLXIP Antibodies)-184 co-target FIH (show CASR Antibodies) tumor suppressor during pathogenesis in the vast majority of head and neck squamous cell carcinoma.

  3. Results suggest that NECAB3 (show NECAB3 Antibodies), a novel Mint3 (show APBA3 Antibodies)-binding protein, activates HIF-1 (show HIF1A Antibodies) to promote normoxic glycolysis and tumorigenicity by forming a ternary complex with Mint3 (show APBA3 Antibodies) and FIH-1.

  4. the levels of both miR (show MLXIP Antibodies)-182 and HIF1alpha (show HIF1A Antibodies) were elevated, while the expression PHD2 (show EGLN1 Antibodies) and FIH1 was downregulated in a mouse model of prostate cancer.

  5. OTUB1 (show OTUB1 Antibodies) is a target for functional hydroxylation by FIH (show CASR Antibodies).

  6. demonstrates that miR (show MLXIP Antibodies)-135b regulates ERalpha (show ESR1 Antibodies), AR and HIF1AN protein levels through interaction with their 3'UTR (show UTS2R Antibodies) regions, and proliferation in ERalpha (show ESR1 Antibodies)-positive BCa (show BLNK Antibodies) and AR-positive PCa (show FLVCR1 Antibodies) cells

  7. Hypoxia, FIH (show CASR Antibodies) inhibitors and mutation of asparagine 242 all potentiated TRPV3 (show TRPV3 Antibodies)-mediated current, without altering TRPV3 (show TRPV3 Antibodies) protein levels, indicating that oxygen-dependent hydroxylation inhibits TRPV3 (show TRPV3 Antibodies) activity.

  8. the nuclear entry of FIH-1 depends on HIF-1alpha (show HIF1A Antibodies)

  9. The kinetic properties of PHD2 (show EGLN1 Antibodies) and FIH (show CASR Antibodies) with respect to oxygen reflect their cellular hypoxia-sensing ability.

  10. data support the concept that FIH-1 may interact with Notch2 (show NOTCH2 Antibodies) and repress its activity, thereby playing a critical role in controlling the survival of vascular endothelial cells

Mouse (Murine) Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) interaction partners

  1. FIH-1 has a role in disrupting the LRRK1/EGFR (show EGFR Antibodies) complex to positively regulate keratinocyte migration

  2. miR (show MLXIP Antibodies)-31/FIH1 pathway associates with liver fibrosis, perhaps by participation in the TGF-beta (show TGFB1 Antibodies)/Smad3 (show SMAD3 Antibodies) signalling of hepatic stellate cells.

  3. gankyrin binds to and sequester factor inhibiting hypoxia-inducible factor-1 (FIH-1), which results in decreased interaction between FIH-1 and hypoxia-inducible factor-1alpha (HIF-1alpha) and increased activity of HIF-1 to promote VEGF production.

  4. Our results define a previously unknown mechanism for keratinocyte fate decisions where Notch (show NOTCH1 Antibodies) signaling potential is, in part, controlled through a miR (show MLXIP Antibodies)-31/FIH-1 nexus.

  5. Overexpression of factor inhibiting HIF-1 enhances vessel maturation and tumor growth via platelet-derived growth factor-C (show PDGFC Antibodies) in osteosarcoma.

  6. FIH (show CASR Antibodies) recognizes distinct molecular features within HIF-alpha1 versus ankyrin repeat containing substrates Notch1 (show NOTCH1 Antibodies)/4 and Gankyrin (show PSMD10 Antibodies).

  7. FIH1 appears to be a suppressor of oxygen-dependent genes in the kidney, operating through HIF-dependent and -independent mechanisms.

  8. Lackin of hypoxia-inducible factor 1 alpha subunit inhibitor exhibit reduced body weight, elevated metabolic rate, hyperventilation, and improved glucose and lipid homeostasis and are resistant to high-fat-diet-induced weight gain and hepatic steatosis.

Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) Antigen Profile

Protein Summary

This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with HIF1AN

  • hypoxia-inducible factor 1 alpha (HIF-1a) antibody
  • hypoxia-inducible factor 1 alpha (hif-1a) antibody
  • Hypoxia-inducible factor 1 alpha (hif1a) antibody
  • hypoxia inducible factor 1, alpha subunit inhibitor (HIF1AN) antibody
  • hypoxia-inducible factor 1, alpha subunit inhibitor (Hif1an) antibody
  • hypoxia-inducible factor 1, alpha subunit inhibitor (hif1an) antibody
  • 2310046M24Rik antibody
  • A830014H24Rik antibody
  • cb728 antibody
  • FIH1 antibody
  • hif-1a antibody
  • hif1a antibody
  • id:ibd5139 antibody

Protein level used designations for HIF1AN

hypoxia-inducible factor 1 alpha , hypoxia inducible factor 1 alpha , Hypoxia-inducible factor 1 alpha , FIH-1 , factor inhibiting HIF-1 , factor inhibiting HIF1 , hypoxia-inducible factor 1-alpha inhibitor , hypoxia-inducible factor asparagine hydroxylase , peptide-aspartate beta-dioxygenase , hypoxia-inducible factor 1, alpha subunit inhibitor

GENE ID SPECIES
445838 Xenopus laevis
100135944 Oncorhynchus mykiss
100174896 Gasterosteus aculeatus
100194993 Salmo salar
55662 Homo sapiens
609221 Canis lupus familiaris
520864 Bos taurus
319594 Mus musculus
309434 Rattus norvegicus
373126 Danio rerio
432095 Xenopus laevis
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