HIF1AN antibody
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- Target See all HIF1AN Antibodies
- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HIF1AN antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human HIF1AN
- Isotype
- IgG
- Top Product
- Discover our top product HIF1AN Primary Antibody
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anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 31-349) antibody
HIF1AN Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reactivity: Human WB, ELISA, IP, IF Host: Mouse Monoclonal 1D8 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 2-254) antibodyHIF1AN Reactivity: Human WB, ELISA, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reactivity: Human WB, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (N-Term) antibodyHIF1AN Reactivity: Human, Rabbit, Horse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reactivity: Human WB, IF Host: Mouse Monoclonal 931CT3-1-1 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 286-316), (C-Term) antibodyHIF1AN Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB10747 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN Reactivity: Human, Mouse, Rat WB, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyHIF1AN Reactivity: Human, Mouse, Rat WB, IHC, IP, IF, ChIP, IC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:500-1:2000, IHC 1:50-1:300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.6 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
- Alternative Name
- HIF1AN (HIF1AN Products)
- Synonyms
- FIH1 antibody, 2310046M24Rik antibody, A830014H24Rik antibody, cb728 antibody, id:ibd5139 antibody, hypoxia inducible factor 1 alpha subunit inhibitor antibody, hypoxia-inducible factor 1, alpha subunit inhibitor antibody, hypoxia inducible factor 1, alpha subunit inhibitor antibody, hypoxia-inducible factor 1, alpha subunit inhibitor S homeolog antibody, HIF1AN antibody, Hif1an antibody, hif1an antibody, hif1an.S antibody
- Background
- Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm.
- Molecular Weight
- 40 kDa
- NCBI Accession
- NP_060372
- UniProt
- Q9NWT6
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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