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anti-Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) Antibodies

The protein encoded by HIF3A is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). Additionally we are shipping HIF3A Proteins (4) and HIF3A Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HIF3A 53417 Q0VBL6
HIF3A 64345 Q9JHS2
HIF3A 64344 Q9Y2N7
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Top anti-HIF3A Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-HIF3A Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot using Affinity Purified anti-Hif3A antibody shows detection of a band ~72 kDa corresponding to mouse Hif3A (arrowhead).   Approximately 10 µg of a CoCl2 treated 3T3 cell lysate (lane 1) and control 3T3 cell lysate (lane 2) were separated by 4-20% SDS-PAGE and transferred onto nitrocellulose.  Treatment of exponentially growing 3T3 cells with 130 µM CoCl2 for 6 h at 37° C effectively mimics hypoxia.   After blocking the membrane was probed overnight at 4° C with the primary antibody diluted to 1:1,600.  The membrane was washed and reacted with a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX (611-132-122) for 45 min at room temperature. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc.  Other detection systems will yield similar results. 100 μg Log in to see 2 to 3 Days
$369.00
Details
Mouse Rabbit Un-conjugated EIA, IF, IHC (p), WB Western blot using antibody ABIN118015 shows detection of a band ~72 kDa corresponding to mouse Hif3a (arrowhead). Approximately 10 ug of a CoCl2 treated 3T3 cell lysate (lane 1) and control 3T3 cell lysate (lane 2) were separated by 4-20% SDS-PAGE and transferred onto nitrocellulose. Treatment of exponentially growing 3T3 cells with 130 uM CoCl2 for 6 h at 37° C effectively mimics hypoxia. After blocking the membrane was probed overnight at 4° C with the primary antibody diluted to 1:1,600. The membrane was washed and reacted with a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] MX for 45 min at room temperature. IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IF, IP, WB 0.1 mL Log in to see 5 to 7 Days
$391.13
Details
Rat Rabbit Un-conjugated WB Anti-HIF3 antibody, Western blotting WB: Rat Brain Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of HIF3 alpha expression in HeLa (A), HepG2 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB Western blot analysis of HIF3A Antibody in extracts from Rat brain cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$493.17
Details

HIF3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HIF3A Antibodies

  1. Mouse (Murine) Polyclonal HIF3A Primary Antibody for EIA, IF - ABIN118015 : Bruder, Naber, Grosch, Koslowski, Benesch, Budde, Hailer, Jacksch, Erbel, Sabin,: [New health care delivery model in cardiology -- Myocardial Infarction Network Essen] in Herz 2007 (PubMed)
    Show all 7 references for ABIN118015

  2. Human Polyclonal HIF3A Primary Antibody for IHC, WB - ABIN2778530 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 references for ABIN2778530

  3. Mouse (Murine) Polyclonal HIF3A Primary Antibody for ELISA, WB - ABIN100475 : Takeda, Ho, Takeda, Duan, Nagy, Fong: Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2. in Molecular and cellular biology 2006 (PubMed)

More Antibodies against HIF3A Interaction Partners

Cow (Bovine) Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

Zebrafish Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

Mouse (Murine) Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

  1. Report suggests that BV-2 microglial cells express HIF-3a under inflammatory conditions and that its activation differed from that of HIF-1a (show HIF1A Antibodies)

  2. mRNA of HIF-2alpha (show EPAS1 Antibodies) and Ets-1 (show ETS1 Antibodies) were significantly increased by HIF-3alpha ablation. Both factors activate the VE-cadherin (show CDH5 Antibodies) gene, the transcriptional repression of these factors by HIF-3alpha is important for silencing the irrelevant expression of the VE-cadherin (show CDH5 Antibodies) gene.

  3. our data indicated that Tnni2K175del mutation led to abnormally increased hif3a and decreased vegf in bone, which explain, at least in part, the small body size of Tnni2K175del mice

  4. Anoxia preconditioning increases anti-ischemic neuronal resistance which to a certain extent correlates with the changes of HIF-1alpha (show HIF1A Antibodies) and HIF-3alpha expression.

  5. alternative splicing and expression of IPAS is induced by hypoxia.

  6. By generating mice with a targeted disruption of the NEPAS/HIF-3alpha locus, it was found that homozygous mutant mice, NEPAS/HIF-3alpha(-/-), were viable but displayed enlargement of the right ventricle and impaired lung remodeling.

  7. Identity of third HIF alpha class member, HIF-3alpha. mRNA expression information by mouse MTN. Experimental proof of dimerization with ARNT/HIF-1beta (show ARNT Antibodies).

Human Hypoxia Inducible Factor 3, alpha Subunit (HIF3A) interaction partners

  1. The association between increased DNA methylation (show HELLS Antibodies) at HIF3A and increased adiposity is present in neonates.

  2. HIF3A DNA Methylation Is Associated with Childhood Obesity and ALT

  3. HIF3alpha has a transcriptional regulatory function, which negatively affects gene expression by competing with HIF1alpha (show HIF1A Antibodies) and HIF2alpha (show EPAS1 Antibodies) in binding to transcriptional elements in target genes during hypoxia. (Review)

  4. A DNA methylation (show HELLS Antibodies) variant in HIF3A was associated with BMI changes through interactions with total or supplemental vitamin B2, vitamin B12 (show NDUFB3 Antibodies), and folate.

  5. Here we provide evidence for the miRNA mediated regulation of HIF3a by hypoxia responsive miRNAs in STS (show STS Antibodies), which may help to tightly regulate and fine-tune the hypoxic response.

  6. The Inhibitory Per/Arnt (show ARNT Antibodies)/Sim (show SIM2 Antibodies) (PAS (show PASK Antibodies)) domain protein (IPAS) is a splice variant of hypoxia-inducible factor (HIF)-3alpha, and possesses two entirely different functions. The results strongly suggest that IPAS is a nucleocytoplasmic shuttling protein.

  7. the transcription of HIF-3alpha4 was silenced by the promoter DNA methylation (show HELLS Antibodies) in meningiomas, and inducible HIF-3alpha4 impaired angiogenesis, proliferation, and metabolism/oxidation in hypervascular meningiomas

  8. HIF3A is regulated by hypoxia in the developing human lung.

  9. Hypoxia upregulated transcription from all three alternative HIF-3alpha promoters. siRNA experiments showed that this induction is mediated specifically by HIF-1 (show HIF1A Antibodies) and not by HIF-2.

  10. multiple splice variants of locus are targets of the von Hippel-Lindau E3 ubiquitin ligase (show MUL1 Antibodies) complex

HIF3A Antigen Profile

Protein Summary

The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with HIF3A

  • hypoxia inducible factor 3, alpha subunit (HIF3A) antibody
  • hypoxia-inducible factor 1, alpha subunit, like (hif1al) antibody
  • hypoxia inducible factor 3, alpha subunit (Hif3a) antibody
  • bHLHe17 antibody
  • HIF-3A antibody
  • HIF3A antibody
  • IPAS antibody
  • Mop7 antibody
  • NEPAS antibody
  • PASD7 antibody
  • zgc:63965 antibody

Protein level used designations for HIF3A

hypoxia inducible factor 3, alpha subunit , Hif3a , Hif3a-like , hypoxia-inducible factor 3 alpha subunit , hypoxia-inducible factor 3-alpha , hypoxia-inducible factor-3 alpha , hypoxia-inducible factor 3-alpha-like , HIF-3-alpha , HIF3-alpha , HIF3-alpha-1 , basic-helix-loop-helix-PAS protein MOP7 , hypoxia inducible factor three alpha , inhibitory PAS domain protein , member of PAS protein 7 , neonatal and embryonic PAS , HIF-3 alpha , HIF3 alpha 1 , hypoxia inducible factor 3 alpha , hypoxia inducible factor 3a , hypoxia-inducible factor 3 alpha , PAS domain-containing protein 7 , class E basic helix-loop-helix protein 17

GENE ID SPECIES
281815 Bos taurus
393376 Danio rerio
456149 Pan troglodytes
100135687 Ovis aries
100413902 Callithrix jacchus
100442498 Pongo abelii
100473029 Ailuropoda melanoleuca
100582446 Nomascus leucogenys
53417 Mus musculus
64345 Rattus norvegicus
64344 Homo sapiens
476429 Canis lupus familiaris
100621574 Sus scrofa
507699 Bos taurus
100071095 Equus caballus
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