anti-Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) Antibodies

The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Additionally we are shipping Immunoglobulin (CD79A) Binding Protein 1 Kits (8) and Immunoglobulin (CD79A) Binding Protein 1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IGBP1 3476 P78318
IGBP1 58845 O08836
IGBP1 18518 Q61249
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Top anti-Immunoglobulin (CD79A) Binding Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB IGBP1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35µg/lane).This demonstrates the IGBP1 antibody detected the IGBP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IP, WB Detection of Alpha-4 by Western Blot and Immunoprecipitation. Samples: A. Whole cell lysate (50 mcg) from Ramos (R), K562 (K) and mouse NIH3T3 (M) cells. B. Whole cell lysate (1 mg/IP, 1/4 of IP reaction loaded/lane) from Ramos cells. Antibodies: ABIN151932 used at 0.4 mcg/ml (A) and 1 mcg/ml (B) for WB at 3 mcg/mg lysate for IP. Alpha-4 was also immunoprecipitated by ABIN151931, but not by another Alpha-4 antibody, which are both affinity purified antibodies to upstream epitopes on Alpha-4. Detection: Chemiluminescence with an exposure time of 30 seconds (A and B). 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated FACS, IF HEK293T cells transfected with either RC200387 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-IGBP1 antibody (ABIN2453823), and then analyzed by flow cytometry. Anti-IGBP1 mouse monoclonal antibody (ABIN2453823) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IGBP1 (RC200387). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti CD79A/IGBP-1 Polyclonal Antibody, Unconjugated (ABIN727578) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat lung tissue labeled with Anti-IGBP1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated WB IGBP1 Antibody (Center)  western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the IGBP1 antibody detected the IGBP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western Blot: IGBP1 Antibody [NBP2-16928] - Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE gel, diluted at 1:500. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details
Human Rabbit Cy3 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

IGBP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Immunoglobulin (CD79A) Binding Protein 1 Antibodies

  1. Human Polyclonal IGBP1 Primary Antibody for IP, WB - ABIN151932 : LeNoue-Newton, Watkins, Zou, Germane, McCorvey, Wadzinski, Spiller: The E3 ubiquitin ligase- and protein phosphatase 2A (PP2A)-binding domains of the Alpha4 protein are both required for Alpha4 to inhibit PP2A degradation. in The Journal of biological chemistry 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Immunoglobulin (CD79A) Binding Protein 1 Interaction Partners

Human Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) interaction partners

  1. Knockdown of Alpha4 preferentially impacts the expression of PP4c (show PPP4C Antibodies) and PP6c (show PPP6C Antibodies) compared to expression levels of PP2Ac (show PPP2CA Antibodies).

  2. Data show that loss of epithelial membrane protein 2 (EMP2) is involved in sphingosylphosphorylcholine (SPC (show UCN3 Antibodies))-induced phosphorylation of keratin 8 (show KRT8 Antibodies) (K8) via ubiquitination of protein phosphatase 2 (PP2A (show PPP2R4 Antibodies)) through alpha4 phosphoprotein by caveolin-1 (cav-1 (show CAV1 Antibodies)).

  3. MID1 (show MID1 Antibodies) catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 (show BBOX1 Antibodies) domain disrupt polyubiquitination of alpha4 but not of PP2Ac (show PPP2CA Antibodies) in X-linked Opitz syndrome.

  4. alpha4 is an important regulatory molecule of apoptosis and Bcl-xL (show BCL2L1 Antibodies) phosphorylation induced by BCR (show BCR Antibodies) crosslinking.

  5. the alpha4 N-terminus binding to endogenous PP2Ac (show PPP2CA Antibodies) and PABP (show PABPC1 Antibodies), and the C-terminus to EDD (show UBR5 Antibodies), is reported.

  6. A potential important role of alpha4 in control of cell migration and/or invasion via the regulation of E-cadherin (show CDH1 Antibodies) expression in bladder urothelial carcinoma.

  7. The structure of alpha45 reveals two distinct surfaces, one that can interact with a negatively charged surface, which is present on PP2A (show PPP2R4 Antibodies), and one that interacts with the Bbox1 (show BBOX1 Antibodies) domain of MID1 (show MID1 Antibodies).

  8. both the C-terminal Mid1 (show MID1 Antibodies)-binding domain and the PP2Ac (show PPP2CA Antibodies)-binding determinants are required for Alpha4-mediated protection of PP2Ac (show PPP2CA Antibodies) from polyubiquitination and degradation.

  9. IGBP-1 is expressed universally in advanced lung adenocarcinomas, and its overexpression is significantly related to outcome.

  10. Data show that in addition to PP2Ac (show PPP2CA Antibodies), alpha4 interacts with EDD (show UBR5 Antibodies) and PABP (show PABPC1 Antibodies), suggesting its involvement in multiple steps in the mTOR (show FRAP1 Antibodies) pathway that leads to translation initiation and cell-cycle progression.

Mouse (Murine) Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) interaction partners

  1. both the C-terminal Mid1 (show MID1 Antibodies)-binding domain and the PP2Ac (show PPP2CA Antibodies)-binding determinants are required for Alpha4-mediated protection of PP2Ac (show PPP2CA Antibodies) from polyubiquitination and degradation.

  2. results show that alpha4, a noncatalytic subunit of protein phosphatase 2A, is required to repress apoptosis in murine cells

  3. alpha4 expression differentially increased or decreased phosphorylation of endogenous phosphoproteins, consistent with opposing effects on PP2A (show PPP2R2B Antibodies) and PP6

  4. Alpha4 (Igbp1) plays a required role in regulating the assembly and maintenance of adaptive PP2A (show PPP2R2B Antibodies) phosphatase complexes.

Immunoglobulin (CD79A) Binding Protein 1 (IGBP1) Antigen Profile

Protein Summary

The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.

Gene names and symbols associated with IGBP1

  • immunoglobulin binding protein 1 (IGBP1) antibody
  • immunoglobulin binding protein 1 (Igbp1) antibody
  • immunoglobulin (CD79A) binding protein 1 (igbp1) antibody
  • immunoglobulin-binding protein 1 pseudogene (LOC709194) antibody
  • immunoglobulin (CD79A) binding protein 1 (Igbp1) antibody
  • immunoglobulin (CD79A) binding protein 1 L homeolog (igbp1.L) antibody
  • immunoglobulin (CD79A) binding protein 1-like (LOC534155) antibody
  • immunoglobulin (CD79A) binding protein 1 (IGBP1) antibody
  • AI115586 antibody
  • AI662457 antibody
  • ALPHA-4 antibody
  • AW208785 antibody
  • C81413 antibody
  • fc70b08 antibody
  • fi33h08 antibody
  • ibp1 antibody
  • IGBP1 antibody
  • MGC83250 antibody
  • MGC147560 antibody
  • p52 antibody
  • Pc52 antibody
  • Tap42 antibody
  • wu:fc70b08 antibody
  • wu:fi33h08 antibody
  • zgc:55347 antibody

Protein level used designations for IGBP1

B cell signal transduction molecule alpha 4 , B-cell signal transduction molecule alpha 4 , CD79a-binding protein 1 , bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ) , immunoglobulin-binding protein 1 , protein alpha-4 , protein phosphatase 2/4/6 regulatory subunit , protein phosphatase 2A, regulatory subunit alpha-4 , renal carcinoma antigen NY-REN-16 , alpha4 phosphoprotein , immunoglobulin binding protein 1 , alpha 4 , lymphocyte signal transduction molecule alpha 4 , phosphoprotein, component, 52 kDa , immunoglobulin (CD79A) binding protein 1

GENE ID SPECIES
3476 Homo sapiens
58845 Rattus norvegicus
406843 Danio rerio
709194 Macaca mulatta
480950 Canis lupus familiaris
18518 Mus musculus
414701 Xenopus laevis
534155 Bos taurus
694632 Macaca mulatta
779894 Xenopus (Silurana) tropicalis
100296883 Bos taurus
100154214 Sus scrofa
100733701 Cavia porcellus
768951 Gallus gallus
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