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The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Additionally we are shipping INHBB Kits (31) and INHBB Proteins (26) and many more products for this protein.
Showing 10 out of 119 products:
Human Polyclonal INHBB Primary Antibody for EIA, IHC (p) - ABIN952903
Ewens, Stewart, Ankener, Urbanek, McAllister, Chen, Baig, Parker, Margulies, Legro, Dunaif, Strauss, Spielman: Family-based analysis of candidate genes for polycystic ovary syndrome. in The Journal of clinical endocrinology and metabolism 2010
Show all 2 references for ABIN952903
Mouse (Murine) Polyclonal INHBB Primary Antibody for IHC (p), WB - ABIN655083
Canzian, Cox, Setiawan, Stram, Ziegler, Dossus, Beckmann, Blanché, Barricarte, Berg, Bingham, Buring, Buys, Calle, Chanock, Clavel-Chapelon, DeLancey, Diver, Dorronsoro, Haiman, Hallmans, Hankinson, Hunter, Hüsing, Isaacs, Khaw, Kolonel, Kraft, Le Marchan: Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium. in Human molecular genetics 2010
Human Polyclonal INHBB Primary Antibody for ELISA, WB - ABIN561500
Brozzetti, Alimohammadi, Morelli, Minarelli, Hallgren, Giordano, De Bellis, Perniola, Kämpe, Falorni: Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease. in The Journal of clinical endocrinology and metabolism 2015
The present study demonstrated that EGF (show EGF Antibodies) controlled expression of three activin (show Actbeta Antibodies) subunits (inhbaa (show INHBA Antibodies), inhbab and inhbb) in the follicle cells via diverse signaling pathways.
whereas the inhibitory effect of hCG (show CGA Antibodies) on activin betaB expression is likely mediated by PKA-independent pathway(s).
Activin (show Actbeta Antibodies) betaA is involved in promoting ovary and follicle growth, whereas activin betaB may have a tonic role throughout follicle development but becomes critical at the late stage of oocyte maturation and/or ovulation.
point mutation enhances the affinity of Noggin2 to ActivinB, while weakens its affinity to BMP.
Noggin2 protected the developing forebrain from inhibition by Activin B (show Actbeta Antibodies) and XWnt8 (show WNT8A Antibodies) signaling.
A new role for activin B (show Actbeta Antibodies) during gastrulation involves cell cycle arrest in the involuting dorsal axial mesoderm.
Used monoclonal antibody to xenopus laevis Inhbb in ELISA for detection of human Inhbb.
Data suggest Inhbb is physiologically essential for early folliculogenesis; Inhbb appears to participate in regulation of cell cycle progression, apoptosis, and steroidogenesis (estradiol/progesterone synthesis) in ovarian granulosa cells in culture.
Activin B (show Actbeta Antibodies), a transforming growth factor beta - related ligand, is upregulated during tumorigenesis and drives the loss of insulin (show INS Antibodies) expression and beta-cell maturity in a mouse insulinoma (show RPS15 Antibodies) model.
in mammalian spinal cord, Tgfbeta (show TGFB1 Antibodies) ligands and ActB (show ACTB Antibodies) together support oligodendrocyte development and myelin formation
No differences were observed in fasting glucose/insulin (show INS Antibodies) levels, glucose tolerance, insulin (show INS Antibodies) sensitivity, or insulin (show INS Antibodies) secretion in comparing young or older males on in comparing insulin (show INS Antibodies) secretion from islets of wild type or activin B (show Actbeta Antibodies) knockout males.
There is a dramatic induction of Inhbb mRNA, e (show HAMP Antibodies)ncoding the activin beta(B)-subunit, in liver challenged with lipopolysaccharide, slight (show Actbeta Antibodies)ly preceding an increase in Smad1/5/8 phosphorylation and Hamp m (show HAMP Antibodies)RNA.
the transition between stem cells and committed progenitors is neither sharp nor irreversible and GDF11 (show GDF11 Antibodies), ACTbetaB and FST (show FST Antibodies) are crucial components of a circuit that controls both total cell number and the ratio of neuronal versus glial cells in this system
These data support the role of proconvertase PCSK5 in the processing of ovarian inhibin subunits during folliculogenesis.
Maintenance of female germ cells hinge upon a delicate balance between positive (WNT4 (show WNT4 Antibodies) and beta-catenin (show CTNNB1 Antibodies)) and negative (activin betaB) regulators derived from the somatic cells in the fetal ovary.
Inhbb-deficient mice have failure of eyelid fusion at birth and demonstrate more severe effects on somatic growth and survival.
Activin (show Actbeta Antibodies) affects both stromal cells and keratinocytes in normal and wounded skin, and the effect on keratinocytes is dose-dependent in vivo.
The Sertoli cell hormones inhibin-B and anti Mullerian hormone (show AMH Antibodies) have different patterns of secretion in prepubertal cryptorchid boys.
Pregnant Han Chinese women carrying the rs7579169 CC genotype and G-G-C haplotype are significantly more likely to develop pre-eclampsia, especially late-onset and multiparous cases.
We report here an original observation that activin-B (show Actbeta Antibodies) is upregulated in the human idiopathic pulmonary fibrosis lung.
reduction of RhoA (show RHOA Antibodies) signaling by Activin B (show Actbeta Antibodies) together with persistent Rac1 activity is a prerequisite for inducing an invasive phenotype in clear cell renal cell carcinoma (show MOK Antibodies).
inhibin B and anti-Mullerian hormone (show AMH Antibodies) serum concentrations did not provide an additional diagnostic tool for male infertility
Activin-A (show INHBA Antibodies) and -B are abundantly expressed in mesothelioma tumor tissue.
Activin A (show INHBA Antibodies), B, and AB have similar effects on steroidogenesis in human granulosa cells; in contrast, activin (show Actbeta Antibodies) AC is not biologically active and does not act as a competitive antagonist.
Serum inhibin levels correlate with clinical characteristics and mortality in epithelial ovarian cancer patients.
inhibin B levels, but not FSH (show BRD2 Antibodies), are increased in primary hypothyroidism, which is consistent with a hypogonadotrophic hypogonadal (show GNRH1 Antibodies) state affecting the reproductive segment of the gonadotrophic axis
Data show that expression of activin A (show INHBA Antibodies) and B was increased in many cancer cell lines.
An increased expression of Inhibin-beta B was found in oocytes collected from large and medium follicles compared with small follicles before or after in oocyte vitro maturation.
our data indicate that miR (show MYLIP Antibodies)-34a plays an important role in granulosa cell apoptosis by targeting the INHBB gene in the porcine ovary
results indicated that boar testis produces inhibin A and inhibin B during the infantile period but inhibin A is the predominant form towards puberty and molecular weight forms of inhibin and the sites of production change with testicular development
The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.
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, inhibin beta subunit B
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, activin AB beta polypeptide
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