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Inhibitor of Growth Family, Member 3 Proteins (ING3)

The protein encoded by ING3 is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. Additionally we are shipping Inhibitor of Growth Family, Member 3 Antibodies (45) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ING3 54556 Q9NXR8
ING3 71777 Q8VEK6
ING3 312154 Q498T3
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Top Inhibitor of Growth Family, Member 3 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,157.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,173.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ING3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Inhibitor of Growth Family, Member 3 (ING3) Interaction Partners

Human Inhibitor of Growth Family, Member 3 (ING3) interaction partners

  1. ING3 levels may serve as a surrogate for growth rate, and suggest possible roles for ING3 in growth and self renewal and related diseases such as cancer.

  2. Downregulated ING3 expression might play an important role in colorectal adenoma-adenocarcinoma sequence.

  3. that ING3 may be an important marker for human hepatocellular carcinoma progression and prognosis, as well as a potential therapeutic target.

  4. Data show that ING3 is degraded by the ubiquitin-proteasome pathway through the SCF(Skp2) complex.

  5. we have isolated a novel ING family gene, p47ING3, which modulates p53 (show TP53 Proteins)-mediated transcription, cell cycle control, and apoptosis. The p47ING3 gene is located at chromosome 7q31.3 and consists of 12 exons that encode 418 amino acids

  6. ING3 may be an important marker for human melanoma progression and prognosis as well as a potential therapeutic target.

  7. ING3 would function as a potential tumor suppressor molecule and that low levels of ING3 may indicate an aggressive nature of head and neck cancer.

  8. Allelic loss and reduced expression of the ING3, a candidate tumor suppressor gene at 7q31, in human head and neck cancers.

Mouse (Murine) Inhibitor of Growth Family, Member 3 (ING3) interaction partners

  1. ING3 levels may serve as a surrogate for growth rate, and suggest possible roles for ING3 in growth and self renewal and related diseases such as cancer.

  2. ING3 is essential for asymmetric cell division during mouse oocyte maturation

Inhibitor of Growth Family, Member 3 (ING3) Protein Profile

Protein Summary

The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

Gene names and symbols associated with ING3

  • inhibitor of growth family, member 3 (ING3)
  • inhibitor of growth family, member 3 (LOC100222182)
  • inhibitor of growth family, member 3 (LOC100354601)
  • inhibitor of growth family, member 3 (Ing3)
  • inhibitor of growth protein 3 (CpipJ_CPIJ009396)
  • inhibitor of growth family, member 3 (ing3)
  • 1300013A07Rik protein
  • Eaf4 protein
  • ING2 protein
  • ING3 protein
  • MEAF4 protein
  • P47ING3 protein
  • zgc:56327 protein

Protein level used designations for ING3

inhibitor of growth family, member 3 , inhibitor of growth protein 3 , inhibitor of growth protein 3-like , p47 regulator protein

GENE ID SPECIES
463679 Pan troglodytes
694005 Macaca mulatta
100056220 Equus caballus
100172464 Pongo abelii
100222182 Taeniopygia guttata
100354601 Oryctolagus cuniculus
100388721 Callithrix jacchus
100465922 Ailuropoda melanoleuca
100512026 Sus scrofa
100578127 Apis mellifera
100603854 Nomascus leucogenys
6041772 Culex quinquefasciatus
417762 Gallus gallus
54556 Homo sapiens
475299 Canis lupus familiaris
71777 Mus musculus
312154 Rattus norvegicus
393911 Danio rerio
379972 Xenopus laevis
513000 Bos taurus
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