Inositol Hexakisphosphate Kinase 1 Proteins (IP6K1)

IP6K1 encodes a member of the inositol phosphokinase family. Additionally we are shipping IP6K1 Antibodies (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IP6K1 50560 Q9ESM0
IP6K1 9807 Q92551
IP6K1 27399 Q6PD10
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Top IP6K1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human GST tag,His tag 50 μg Log in to see 20 to 21 Days
$272.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,210.17
Details
HOST_Escherichia coli (E. coli) Human S tag,His tag   100 μg Log in to see 15 to 18 Days
$688.00
Details

IP6K1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , ,
, , ,
Mouse (Murine)

More Proteins for Inositol Hexakisphosphate Kinase 1 (IP6K1) Interaction Partners

Human Inositol Hexakisphosphate Kinase 1 (IP6K1) interaction partners

  1. provides the first evidence for the involvement of IP6Ks in dynein function and proposes that inositol pyrophosphate-mediated pyrophosphorylation may act as a regulatory signal to enhance dynein-driven transport

  2. IP6K1 is also involved in early cytoskeleton remodeling events during cancer progression.

  3. IP6K1 is a novel CRL4 subunit that transduces UV signals to mediate disassembly of the CRL4-CSN complex, thereby regulating nucleotide excision repair and cell death.

  4. we identified IP6Ks as novel nuclear and cytosolic InsP6- (and InsP5-) dephosphorylating enzymes whose activity is sensitively driven by a decrease in the cellular ATP/ADP ratio

  5. FGF2 (show FGF2 Proteins)-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 (show RUNX2 Proteins) and osteoblast gene expression.

  6. IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus

  7. Results report the characterization of an inhibitor, N(2)-(m-(trifluoromethy)lbenzyl) N(6)-(p-nitrobenzyl)purine (TNP), selective for inositol hexakisphosphate kinases.

Mouse (Murine) Inositol Hexakisphosphate Kinase 1 (IP6K1) interaction partners

  1. IP6K1 regulates energy metabolism via a mechanism that could potentially be targeted in obesity.

  2. provides the first evidence for the involvement of IP6Ks in dynein function and proposes that inositol pyrophosphate-mediated pyrophosphorylation may act as a regulatory signal to enhance dynein-driven transport

  3. IP6K1 is also involved in early cytoskeleton remodeling events during cancer progression.

  4. IP6K1 preferentially bound to the phospholipid phosphatidic acid, and this binding was required for IP6K1 nuclear localization and the regulation of inositol-3-phosphate synthase transcription.

  5. IP6K1 is a novel CRL4 subunit that transduces UV signals to mediate disassembly of the CRL4-CSN complex, thereby regulating nucleotide excision repair and cell death.

  6. present study demonstrates that IP6K1 physiologically regulates GSK3 kinases.

  7. FGF2 (show FGF2 Proteins)-signaling involves the inositol polyphosphate cascade, including inositol hexakisphosphate kinase (IP6K), and demonstrate that IP6K1,2 regulates Runx2 (show RUNX2 Proteins) and osteoblast gene expression.

  8. IP6K1 has a role in regulation of mammalian hemostasis via its control of platelet polyP levels

  9. Mouse embryonic fibroblasts (MEFs) lacking IP6K1 exhibit impaired DNA damage repair via homologous recombination.

  10. Defects in the mutants indicate important roles for IP6K1 and inositol pyrophosphates in several physiological functions

IP6K1 Protein Profile

Protein Summary

This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with IP6K1

  • inositol hexaphosphate kinase 1 (ip6k1)
  • inositol hexakisphosphate kinase 1 (IP6K1)
  • inositol hexaphosphate kinase 1 (Tsp_08677)
  • inositol hexaphosphate kinase 1 (IP6K1)
  • inositol hexakisphosphate kinase 1 (Ip6k1)
  • inositol hexaphosphate kinase 1 (Ip6k1)
  • 1200016D08Rik protein
  • AU022776 protein
  • DKFZp459D1030 protein
  • Ihpk1 protein
  • InsP6 protein
  • InsP6k1 protein
  • IP6K1 protein
  • Itpk6 protein
  • MGC80337 protein
  • PiUS protein

Protein level used designations for IP6K1

inositol hexaphosphate kinase 1 , inositol hexakisphosphate kinase 1 , inositol hexakisphosphate kinase 6 , insP6 kinase 1 , ATP:1D-myo-inositol-hexakisphosphate phosphotransferase , Pi uptake stimulator

GENE ID SPECIES
443957 Xenopus laevis
460379 Pan troglodytes
484765 Canis lupus familiaris
534029 Bos taurus
780040 Xenopus (Silurana) tropicalis
10907113 Trichinella spiralis
100052910 Equus caballus
100171866 Pongo abelii
50560 Rattus norvegicus
9807 Homo sapiens
27399 Mus musculus
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