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ITPK1 Proteins

(Inositol-Tetrakisphosphate 1-Kinase (ITPK1))
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5. This reaction is thought to have regulatory importance, since Ins(3,4,5,6)P4 is an inhibitor of plasma membrane Ca(2+)-activated Cl(-) channels, while Ins(1,3,4,5,6)P5 is not. Also acts as an inositol polyphosphate phosphatase that dephosphorylate Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 to Ins(1,3,4)P3, and Ins(1,3,4,5,6)P5 to Ins(3,4,5,6)P4. May also act as an isomerase that interconverts the inositol tetrakisphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. Probably acts as the rate-limiting enzyme of the InsP6 pathway. Modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain (By similarity). Also phosphorylates Ins(1,3,4)P3 on O-5 and O-6 to form Ins(1,3,4,6)P4, an essential molecule in the hexakisphosphate (InsP6) pathway.
ITPK1 Protein (AA 1-414) (His tag) ITPK1 Protein (AA 1-414) (His tag) ITPK1 Protein (AA 1-414) (His tag) (ABIN7123440)

ITPK1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

ITPK1 Protein (AA 1-314) (GST tag) ITPK1 Protein (AA 1-314) (GST tag) ITPK1 Protein (AA 1-314) (GST tag) (ABIN1308246)

ITPK1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

ITPK1 Protein (AA 1-414) (His tag) ITPK1 Protein (AA 1-414) (His tag) ITPK1 Protein (AA 1-414) (His tag) (ABIN3093199)

Crystallography grade ITPK1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS, Crys

ITPK1 Proteins by Grade

Find ITPK1 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ITPK1 Proteins by Origin

Find ITPK1 Proteins for a variety of species such as anti-Human ITPK1, anti-Chicken ITPK1, anti-Cow ITPK1. The species listed below are among those available. Click on a link to go to the corresponding products.

ITPK1 Proteins by Source

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ITPK1 Proteins by Protein Type

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ITPK1 Proteins by Application

Find ITPK1 Proteins validated for a specific application such as ELISA, WB, AbP, SDS. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ITPK1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123440
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308246
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3093199
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136320
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723914
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2723915
Quantity 20 μg
Datasheet Datasheet
Reactivity Entamoeba histolytica
Source Yeast
Validations
Cat. No. ABIN1659096
Quantity 1 mg
Datasheet Datasheet
Reactivity Zebrafish (Danio rerio)
Source Yeast
Validations
Cat. No. ABIN1677535
Quantity 1 mg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1630973
Quantity 1 mg
Datasheet Datasheet
Reactivity Cow
Source Yeast
Validations
Cat. No. ABIN1459571
Quantity 1 mg
Datasheet Datasheet

Aliases for ITPK1 Proteins

inositol-tetrakisphosphate 1-kinase (ITPK1) Proteins
inositol 1,3,4-triphosphate 5/6 kinase (Itpk1) Proteins
inositol-tetrakisphosphate 1-kinase L homeolog (itpk1.L) Proteins
inositol-tetrakisphosphate 1-kinase a (itpk1a) Proteins
inositol-tetrakisphosphate 1-kinase (Itpk1) Proteins
BC031182 Proteins
ITRPK1 Proteins
wu:fj15d08 Proteins
zgc:56075 Proteins
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