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Inositol-Trisphosphate 3-Kinase C Proteins (ITPKC)

ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. Additionally we are shipping ITPKC Antibodies (55) and ITPKC Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITPKC 233011 Q7TS72
ITPKC 80271 Q96DU7
ITPKC 308451 Q80ZG2
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Top ITPKC Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,971.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ITPKC Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,
Rat (Rattus)

More Proteins for Inositol-Trisphosphate 3-Kinase C (ITPKC) Interaction Partners

Mouse (Murine) Inositol-Trisphosphate 3-Kinase C (ITPKC) interaction partners

  1. These data show that the absence of expression of the three isoenzymes of Itpk does not prevent the formation of IP5 and IP6 (show GPRIN2 Proteins), at least in mouse embryonic fibroblasts.[Itpka (show ITPKA Proteins), Itpkb (show ITPKB Proteins), Itpkc]

Human Inositol-Trisphosphate 3-Kinase C (ITPKC) interaction partners

  1. ITPKC polymorphisms are associated with Kawasaki disease.

  2. SNP rs7251246 in ITPKC is associated with the severity of Kawasaki disease

  3. Our results identify a novel polymorphism for renal function and highlight the importance of ITPKC as a key molecule to regulate calcium signaling.

  4. a combinatorial association between ITPKC (rs28493229) and CASP3 (show CASP3 Proteins) (rs113420705) was found in coronary artery lesion formation (P = 0.0227, OR: 3.06)in Taiwanese population

  5. functional studies demonstrated that PPP3CC positively influences the protein level of ITPKC, likely by inhibiting phosphorylation of ITPKC and consequently preventing ITPKC from ubiquitin-mediated protein degradation

  6. Functional single-nucleotide polymorphisms in ITPKC and CASP3 (show CASP3 Proteins) are associated with susceptibility to Kawasaki's disease (KD).

  7. the functional polymorphism rs28493229 in ITPKC significantly contributes to the risk of Kawasaki disease.

  8. The C allele of the ITPKC gene rs2290692 is linked to a significantly higher risk for KD in the Han Chinese population studied.

  9. ITPKC susceptibility in Kawasaki syndrome is related to its synergy with environmental triggers, such as thimerosal, which alter calcium homeostasis and promote oxidative stress.

  10. The study failed to prove any association between SNP rs28493229 of ITPKC gene and Kawasaki disease/coronary artery lesions in Chinese patients.

ITPKC Protein Profile

Protein Summary

This gene encodes a member of the inositol 1,4,5-trisphosphate

Gene names and symbols associated with ITPKC

  • inositol-trisphosphate 3-kinase C (ITPKC)
  • inositol-trisphosphate 3-kinase C (itpkc)
  • inositol 1,4,5-trisphosphate 3-kinase Ca (itpkca)
  • inositol 1,4,5-trisphosphate 3-kinase C (LOC100354575)
  • inositol 1,4,5-trisphosphate 3-kinase C (ITPKC)
  • inositol 1,4,5-trisphosphate 3-kinase C (Itpkc)
  • inositol-trisphosphate 3-kinase C (Itpkc)
  • 9130023N17Rik protein
  • fi30c01 protein
  • IP3-3KC protein
  • IP3KC protein
  • itpkc protein
  • wu:fi30c01 protein

Protein level used designations for ITPKC

inositol-trisphosphate 3-kinase C , inositol 1,4,5-trisphosphate 3-kinase C , inositol-trisphosphate 3-kinase C-like , IP3 3-kinase C , IP3K C , insP 3-kinase C , InsP 3 kinase C , IP3K-C

GENE ID SPECIES
100524376 Sus scrofa
468885 Pan troglodytes
494865 Xenopus laevis
534051 Bos taurus
562919 Danio rerio
612489 Canis lupus familiaris
779709 Xenopus (Silurana) tropicalis
100064775 Equus caballus
100354575 Oryctolagus cuniculus
100392537 Callithrix jacchus
100448277 Pongo abelii
100471702 Ailuropoda melanoleuca
100583847 Nomascus leucogenys
233011 Mus musculus
80271 Homo sapiens
308451 Rattus norvegicus
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