Insulin-Like Growth Factor 2 MRNA Binding Protein 1 Proteins (IGF2BP1)

IGF2BP1 encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. Additionally we are shipping IGF2BP1 Antibodies (64) and IGF2BP1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
IGF2BP1 10642 Q9NZI8
IGF2BP1 140486 O88477
IGF2BP1 303477 Q8CGX0
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Top IGF2BP1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$333.33
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$740.00
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,657.50
Details

IGF2BP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Top referenced IGF2BP1 Proteins

  1. Human IGF2BP1 Protein expressed in Wheat germ - ABIN1307552 : Hellbach, Weise, Vezzali, Wahane, Heidrich, Roidl, Pruszak, Esser, Vogel: Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome. in Human molecular genetics 2014 (PubMed)

More Proteins for Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) Interaction Partners

Human Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. The regions encoding 71 microRNAs (miRs) were deleted in at least 25% of tumor specimens. Five of these recurrently deleted miRs targeted the insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) gene product, and a correlating 100-fold upregulation of IGF2BP1 mRNA was seen in tumor specimens

  2. Insight into molecular interactions between CRD-BP and MITF (show MITF Proteins) mRNA.

  3. IGF2BP1 indirectly potentiates ETV6 (show ETV6 Proteins)/RUNX1 (show RUNX1 Proteins)-RAC1-STAT3 (show STAT3 Proteins) signaling axis by sustaining appropriate ETV6 (show ETV6 Proteins)/RUNX1 (show RUNX1 Proteins) and STAT3 (show STAT3 Proteins) transcript levels in REH (show CES1 Proteins) cells.

  4. The findings indicate that the tumor-suppressive roles of the let-7 family are antagonized by a potent and self-promoting triangle consisting of IGF2BP1 (potentially all IGF2BPs), LIN28B and HMGA2.

  5. The results from this study demonstrate the potential importance of the two-stem-loop motif as a target region for the inhibition of the CRD-BP-GLI1 (show GLI1 Proteins) RNA interaction and Hedgehog (show SHH Proteins) signaling pathway.

  6. these findings suggest that miR (show MLXIP Proteins)-150 functions as a tumor suppressor in Osteosarcoma (OS) partially by targeting IGF2BP1

  7. ETV6 (show ETV6 Proteins)/RUNX1 (show RUNX1 Proteins) transcript is a target of RNA-binding protein (show PTBP1 Proteins) IGF2BP1 in t(12;21)(p13;q22)-positive acute lymphoblastic leukemia.

  8. Data show that ONECUT2, IGF2BP1, and ANXA2 (show ANXA2 Proteins) proteins were confirmed to be microRNA-9 (miR (show MLXIP Proteins)-9) targets and aberrantly upregulated in hepatocellular carcinoma (HCC (show FAM126A Proteins)).

  9. The tumor-suppressive role of stromal IMP1 (show IMPA1 Proteins) and its ability to modulate protumorigenic factors suggest that IMP1 (show IMPA1 Proteins) status is important for the initiation and growth of epithelial tumors

  10. IGF2BP1 as a direct and functional target of miR (show MLXIP Proteins)-196b.

Mouse (Murine) Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. This study showed that Zipcode binding protein 1 (ZBP1) is an mRNA-binding protein that regulates the local translation of proteins, including actin, in the growth cone and is required for Shh (show SHH Proteins)-mediated axon guidance.

  2. The tumor-suppressive role of stromal IMP1 (show IMPA1 Proteins) and its ability to modulate protumorigenic factors suggest that IMP1 (show IMPA1 Proteins) status is important for the initiation and growth of epithelial tumors

  3. High CRD-BP expression is associated with Breast Tumor.

  4. Results identify IGF2BP1 (show B4GALNT2 Proteins) as a critical translational regulator of cIAP1 (show BIRC2 Proteins)-mediated apoptotic resistance in rhabdomyosarcoma.

  5. This study demonstrate that ZBP1 (show ZBP1 Proteins) and the phosphorylation of ZBP1 (show ZBP1 Proteins) are required for attractive guidance of cortical neurons, and appropriate filopodial dynamics.

  6. IMP1 (show IMPA1 Proteins) plays a role in regulating the packaging of MLV genomic RNA and can be used for improving production of retroviral vectors

  7. WAP (show Wap Proteins)-CRD-BP mice are a novel model for mammary neoplasia and might provide insights into human breast cancer biology.

  8. IMP-1 (show IMPA1 Proteins) associates with HuD (show ELAVL4 Proteins) and G3BP-1 (show G3BP1 Proteins) proteins in an RNA-dependent manner and binds directly to tau mRNA. We also show an RNA-dependent association between G3BP-1 (show G3BP1 Proteins) and HuD (show ELAVL4 Proteins) proteins

Zebrafish Insulin-Like Growth Factor 2 MRNA Binding Protein 1 (IGF2BP1) interaction partners

  1. Two KH domains of CRD-BP are required for efficient binding to oncogenic mRNAs and for granule formation in zebrafish embryos.

IGF2BP1 Protein Profile

Protein Summary

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with IGF2BP1

  • insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1)
  • insulin-like growth factor 2 mRNA binding protein 1 (Igf2bp1)
  • insulin-like growth factor 2 mRNA binding protein 1 (igf2bp1)
  • AL024068 protein
  • AW549074 protein
  • CRD-BP protein
  • Crdbp protein
  • D030026A21Rik protein
  • D11Moh40e protein
  • D11Moh45 protein
  • IGF2BP1 protein
  • IMP-1 protein
  • Imp1 protein
  • Neilsen protein
  • VICKZ1 protein
  • wu:fi72a06 protein
  • Zbp1 protein
  • zgc:152963 protein

Protein level used designations for IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1 , IGF-II mRNA-binding protein 1 , IGF2 mRNA-binding protein 1 , IMP-1 , VICKZ family member 1 , ZBP-1 , insulin-like growth factor 2 mRNA-binding protein 1 , zip code-binding protein 1 , zipcode-binding protein 1 , coding region determinant-binding protein , coding region determinant binding protein , insulin-like growth factor 2, binding protein 1 , zipcode binding protein 1 , B-actin zipcode-binding protein 1 , insulin-like growth factor 2 binding protein 1 , rZBP-1 , zipcode-binding protein-1

GENE ID SPECIES
455198 Pan troglodytes
100018704 Monodelphis domestica
100055918 Equus caballus
395953 Gallus gallus
10642 Homo sapiens
491064 Canis lupus familiaris
516853 Bos taurus
140486 Mus musculus
303477 Rattus norvegicus
558182 Danio rerio
100620940 Sus scrofa
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