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Negative regulator of beta amyloid peptide production. Additionally we are shipping ITM2C Antibodies (45) and ITM2C Kits (2) and many more products for this protein.
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Both Itm2a (show ITM2A Proteins) and Itm2c were not detected in the epididymis and vas (show AVP Proteins) deferens during sexual maturation.
Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C- terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation (By similarity).
BRICHOS domain containing 2C
, cerebral protein 14
, integral membrane protein 3
, transmembrane protein BRI3