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Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) Proteins (ITGA5)

The product of ITGA5 belongs to the integrin alpha chain family. Additionally we are shipping ITGA5 Antibodies (313) and ITGA5 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ITGA5 16402 P11688
ITGA5 3678 P08648
Rat ITGA5 ITGA5 315346  
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Top ITGA5 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Cow His tag,GST tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$385.00
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$739.20
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$920.54
Details

ITGA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
, ,
Human , , , ,
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More Proteins for Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) Interaction Partners

Mouse (Murine) Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) interaction partners

  1. Gdf-5 (show GDF5 Proteins) induced the expression of the alpha5 sub-unit, while Bmp-7 (show BMP7 Proteins) induced the expression of the alphaV sub-unit.

  2. EGFR (show EGFR Proteins) activation can be regulated by the N-glycosylation of integrin alpha5, which is a novel molecular paradigm for the cross-talk between integrins and growth factor receptors

  3. An (as yet unknown) integrin alpha5-dependent signal extrinsic to the pharyngeal endothelium mediates the formation of the 4th pharyngeal arch arteries through fibronectin (show FN1 Proteins).

  4. Suggest that alpha5beta1-mediated cross-talk between fibronectin (show FN1 Proteins) and oxLDL regulates inflammation in early atherogenesis and that therapeutics that inhibit alpha5 integrins may reduce inflammation without adversely affecting plaque structure.

  5. our data point to a potential role for the fibronectin (show FN1 Proteins)-alpha5beta1 integrin interaction in promoting vascular remodeling during demyelinating disease

  6. high expression of the ppGalNAc-T13 (show GALNT13 Proteins) gene generates tTn (show TTN Proteins) antigen on Syndecan 1 (show SDC1 Proteins), leading to enhanced invasion and metastasis via the formation of a complex consisting of integrin alpha5beta1, Syndecan 1 (show SDC1 Proteins), and MMP-9 (show MMP9 Proteins) in the glycolipid-enriched microdomain/rafts.

  7. Fibronectin (show FN1 Proteins) and integrin alpha5beta1 have critical roles in mouse embryogenesis

  8. It was found that binding between Porphyromonas gingivalis fimbriae and integrin alpha5beta1 on osteoblasts, and subsequent peripheral condensation of actin, are essential for entry of Porphyromonas gingivalis into osteoblasts.

  9. Our study unveils a previously unidentified role of alpha5beta1 integrin as an intermediate signaling molecule in neurotoxic prion (show PRNP Proteins) peptides-microglia interactions.

  10. Fibroblasts require Mena for multiple integrin alpha5beta1-dependent processes involving bidirectional interactions between the extracellular matrix and cytoplasmic focal adhesion proteins.

Human Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) interaction partners

  1. ITGA5 plays an important role in maintaining and regulating the normal migration capacity of dental pulp stem cells.

  2. IGFBP-2 enhances endothelial progenitor cell adhesion to HUVECs via Integrin alpha5beta1. The RGD motif in the IGFBP-2 C-domain is required for interaction with integrin alpha5beta1.

  3. knockdown of PTTG1 (show PTTG1 Proteins) increased expression of integrin alpha 4 (ITGA4 (show ITGA4 Proteins)), ITGA5, and integrin beta 1 (ITGB1 (show ITGB1 Proteins)); otherwise, RhoA (show RHOA Proteins) expression was significantly decreased

  4. Genetic and Immunohistochemical Expression of Integrins ITGAV (show ITGAV Proteins), ITGA6 (show ITGA6 Proteins), and ITGA3 (show ITGA3 Proteins) As Prognostic Factor for Colorectal Cancer

  5. Data show that the fold changes of very late antigen 5 VLA-5 (integrin alpha-5 beta-1) in CD14 (show NDUFA2 Proteins)+ monocytes were higher than those observed for THP-1 cells.

  6. Data suggest that reduced ability of AnxA6 (show ANXA6 Proteins)-expressing cells to migrate is associated with decreased cell surface expression of integrins alphaVbeta3 and alpha5beta1.

  7. Data suggest that the binding, but not the internalization of photoreceptor outer segments (POS) confers protective effects on retinal pigment epithelium (RPE) cells through the alphavbeta5 integrin/focal adhesion kinase (FAK)/PGC-1alpha pathway.

  8. alpha5beta1 and alphavbeta3 each mediate actin cytoskeletal remodeling in response to stiffening or cyclic stretching of the extracellular matrix.

  9. Data show that a small molecule inhibitor of the MYC (show MYC Proteins) transcription factor can be an effective anticancer agent when delivered using a integrin alphavbeta3 (show ITGAV Proteins) and VLA-4-targeted nanotherapy approach.

  10. Data suggest that Entamoeba histolytica-macrophage contact triggers recruitment of alpha5beta1 integrin (ITGA5/ITGB1 (show ITGB1 Proteins)) and NLRP3 (show NLRP3 Proteins) into intercellular junction, where ITGA5/ITGB1 (show ITGB1 Proteins) undergoes activation by cysteine protease (show CTSB Proteins) on parasite surface.

Cow (Bovine) Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) interaction partners

  1. Putative function of fibronectin (show FN1 Proteins) and its receptor (integrin alpha(5)beta(1)) in male and female gametes during bovine fertilization in vitro.

  2. Results indicate that XIAP (show XIAP Proteins) stabilizes the alpha(5)-integrin-associated focal adhesion complex, thereby further regulating endothelial cell adhesion and migration.

  3. alphavbeta3 integrin engagement in vascular endothelium regulates Ca2 (show CA2 Proteins)+-dependent K+ current

  4. Flow induced alpha2beta1 activation in cells on collagen, but not on fibronectin or fibrinogen. Conversely, alpha5beta1 and alphavbeta3 are activated on fibronectin and fibrinogen, but not collagen.

ITGA5 Protein Profile

Protein Summary

The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Gene names and symbols associated with ITGA5

  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (ITGA5)
  • integrin alpha 5 (fibronectin receptor alpha) (Itga5)
  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide) (Itga5)
  • CD49e protein
  • FNRA protein
  • ITGA5 protein
  • Itga5_retired protein
  • VLA5 protein
  • VLA5A protein

Protein level used designations for ITGA5

integrin, alpha 5 (fibronectin receptor, alpha polypeptide) , CD49 antigen-like family member E , fibronectin receptor alpha polypeptide , fibronectin receptor subunit alpha , integrin alpha-5 , integrin alpha-F , VLA-5 , fibronectin receptor, alpha subunit , very late activation protein 5, alpha subunit , integrin alpha 5 (fibronectin receptor alpha)

GENE ID SPECIES
486493 Canis lupus familiaris
100606925 Nomascus leucogenys
16402 Mus musculus
3678 Homo sapiens
315346 Rattus norvegicus
281873 Bos taurus
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