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The ITGA6 protein product is the integrin alpha chain alpha 6. Additionally we are shipping ITGA6 Antibodies (361) and ITGA6 Kits (6) and many more products for this protein.
Showing 9 out of 14 products:
Equine herpesvirus type 1 infection significantly decreased the expression of integrin alpha 6 in nasal mucosa epithelial cells.
interaction of alpha6beta1 in embryonic stem cells (ECCs) with laminin-1 (show LAMA1 Proteins) activates alpha6beta1/CD151 (show CD151 Proteins) signaling which programs ESCs (show NR2E3 Proteins) toward the endothelial cells lineage fate
Exome sequencing analysis between SM/J and A/J mice identified 4 genes (Itga6, Zak (show ZAK Proteins), Gpr155, and Mtx2 (show MTX2 Proteins)) with nonsynonymous coding SNPs. These four genes might be candidate genes for type 2 diabetes caused by gene-gene interactions.
Immunohistological analysis of the tumors showed that Tie2 (show TEK Proteins)-dependent a6 gene deletion was associated with reduced tumor vascularization and with reduced infiltration of proangiogenic Tie2 (show TEK Proteins)-expressing macrophages
CD29 (show ITGB1 Proteins) and CD49f have a critical role of in mediating cancer metastasis.
NLGN1 (show NLGN1 Proteins) and alpha6 integrin preferentially colocalize in the mature retinal vessels, whereas NLGN1 (show NLGN1 Proteins) deletion causes an aberrant VE-cadherin (show CDH5 Proteins), laminin and alpha6 integrin distribution in vessels
alpha6 integrin is an essential upstream regulator of the IGF-1R (show IGF1R Proteins) survival pathway that regulates the activity level of caspase-3 (show CASP3 Proteins) for it to signal differentiation initiation of lens epithelial cells.
Deficiency of integrin alpha(6)beta(4) is modestly but significantly suppressed reporter-gene transduction by papillomaviruses in conditional integrin beta(4 (show ITGB4 Proteins)) knockout mice.
The alpha6beta1 integrin is a netrin-4 (show NTN4 Proteins) receptor in endothelial cells.
PHLDA1 (show PHLDA1 Proteins) expression marks the putative epithelial stem cells, downregulates ITGA2 (show ITGA2 Proteins) and ITGA6, and contributes to intestinal tumorigenesis
cerebral hypoxia promotes first an endothelial response followed by astrocyte activation, proliferation, and reorganization of astrocyte end-feet, which correlates with increased expression of adhesion molecules alpha 6 beta 4 integrin and dystroglycan
Platelet-enhanced endothelial colony forming cell angiogenesis requires platelet tetraspanin CD151 (show CD151 Proteins) and alpha6beta1 integrin signaling.
these findings identify CD151 (show CD151 Proteins) and its interactions with integrins a3 and a6 as potential therapeutic targets for inhibiting stemness-driving mechanisms and stem cell populations in Glioblastoma.
HIF-dependent regulation of ITGA6 is one mechanism by which sorting for CD49f (+) cells enhances cancer stem cells.
CD49f is a marker of bone marrow mesenchymal stem cells and is correlated with changes in these stem cells under inflammatory conditions.
Genetic and Immunohistochemical Expression of Integrins ITGAV (show ITGAV Proteins), ITGA6, and ITGA3 (show ITGA3 Proteins) As Prognostic Factor for Colorectal Cancer
We here identify CD49f and CD34 (show CD34 Proteins) as markers to permit selection of the stem/progenitor cell-like population from human myometrium
integrin alpha6beta4 stimulates invasion by promoting autocrine EGFR (show EGFR Proteins) signaling through transcriptional up-regulation of key EGFR (show EGFR Proteins) family members and by facilitating HGF (show HGF Proteins)-stimulated EGFR (show EGFR Proteins) ligand secretion
Amphiregulin (show AREG Proteins) enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf (show RAF1 Proteins)/MEK (show MAP2K1 Proteins)/ERK (show EPHB2 Proteins)/AP-1 (show FOSB Proteins) pathway.
Unique sites of interaction between alphavbeta6 and uPAR (show PLAUR Proteins) are most likely located in uPAR (show PLAUR Proteins) domains II and III.
our observations suggest that miR (show MLXIP Proteins)-25 is a key regulator of invasiveness in human prostate cancer through its direct interactions with av- and a6-integrin expression
formation of CD151 (show CD151 Proteins)-integrin complex was likely to be a prerequisite for CD151 (show CD151 Proteins)-induced angiogenesis and signaling pathways
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
integrin, alpha 6
, integrin alpha 6 subunit
, integrin alpha chain, alpha 6
, integrin alpha-6
, integrin alpha 6
, integrin alpha-6-like
, CD49 antigen-like family member F
, integrin alpha6B