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Integrin beta 1 Binding Protein 1 Proteins (ITGB1BP1)

The cytoplasmic domains of integrins are essential for cell adhesion. Additionally we are shipping Integrin beta 1 Binding Protein 1 Antibodies (54) and Integrin beta 1 Binding Protein 1 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ITGB1BP1 ITGB1BP1 298914  
ITGB1BP1 9270 O14713
ITGB1BP1 16413 O35671
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Top Integrin beta 1 Binding Protein 1 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 11 to 12 Days
$246.96
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,486.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details

ITGB1BP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Integrin beta 1 Binding Protein 1 (ITGB1BP1) Interaction Partners

Human Integrin beta 1 Binding Protein 1 (ITGB1BP1) interaction partners

  1. The cocrystal structure of ICAP1 in complex with krev (show RAP1B Proteins) interaction trapped protein (KRIT)1 (show KRIT1 Proteins) is characterized here.

  2. The structural basis for KRIT1 (show KRIT1 Proteins) antagonized ICAP1-modulated integrin-beta1 activation.

  3. Annexin A1 (show ANXA1 Proteins) is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway.

  4. Identify ICAP1 as a novel regulator to prevent excessive sprouting angiogenesis.

  5. Site-directed mutagenesis showed that Leu(135), Ile(138), and Ile(139) of Icap1 alpha, and Leu(82) and Tyr (show TYR Proteins)(144), are required for the Icap1 alpha-beta(1) integrin interaction

  6. Integrin-binding protein also interacts with Krit 1 (show KRIT1 Proteins) protein, cause of CCM1 (show KRIT1 Proteins). (ICAP-1, integrin cytoplasmic domain-associated protein 1)

  7. beta(1) integrin viability signal in collagen matrices is transduced by focal adhesion kinase

  8. ICAP-1 shuttles between the nucleus and cytoplasm in a beta1 integrin-dependent manner

  9. TNF-alpha (show TNF Proteins) induced expression of c-IAP1 (show BIRC2 Proteins) and c-IAP2 (show BIRC3 Proteins) via MAP kinases, but not via NF-kappaB (show NFKB1 Proteins), and that MAP kinases participated in the inhibition of apoptosis by induction of c-IAPs in TNF-alpha (show TNF Proteins)-stimulated endothelial cells

  10. integrin cytoplasmic domain-associated protein-1 alpha (icap1alpha) act concordantly to play a critical role in beta1-integrin-mediated cell proliferation.

Mouse (Murine) Integrin beta 1 Binding Protein 1 (ITGB1BP1) interaction partners

  1. The CCM1 (show KRIT1 Proteins) loss resulted in ICAP-1 destabilization, which increased beta1 integrin activation and led to increased RhoA (show RHOA Proteins)-dependent contractility.

  2. Data show that phosphorylation of ICAP-1alpha by CaMKII (show CAMK2G Proteins) controls beta1 integrin activation and cell adhesion.

  3. The ICAP-1 works in concert with kindlin-2 (show FERMT2 Proteins) to control the dynamics of beta1 integrin-containing fibrillar adhesions and, thereby, regulates fibronectin (show FN1 Proteins) deposition and osteoblast mineralization.

  4. Live cell imaging, which was performed in both Icap-1-deficient mouse embryonic fibroblasts and cells expressing active beta(1) integrin, shows that the integrin high affinity state favored by talin is antagonistically controlled by ICAP-1.

  5. ICAP-1 regulates beta1 integrin-dependent cell migration by affecting the pattern of focal adhesion formation.

  6. Identify ICAP1 as a novel regulator to prevent excessive sprouting angiogenesis.

  7. Integrin cytoplasmic domain-associated protein-1 (ICAP-1) binds ROCK to beta1 integrin at the cell membrane (ICAP-1)

  8. ICAP-1 promotes differentiation of osteoprogenitors by supporting their condensation through modulating the integrin high affinity state.

Integrin beta 1 Binding Protein 1 (ITGB1BP1) Protein Profile

Protein Summary

The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.

Gene names and symbols associated with ITGB1BP1

  • integrin beta 1 binding protein 1 (Itgb1bp1)
  • integrin beta 1 binding protein 1 (itgb1bp1)
  • integrin beta 1 binding protein 1 (ITGB1BP1)
  • AI449260 protein
  • AU019480 protein
  • ICAP-1A protein
  • ICAP-1alpha protein
  • ICAP-1B protein
  • Icap1 protein
  • ICAP1A protein
  • ICAP1B protein
  • si:dkey-27p7.1 protein
  • zgc:123198 protein

Protein level used designations for ITGB1BP1

integrin beta-1-binding protein 1 , ICAP-1 , bodenin , integrin cytoplasmic domain-associated protein 1 , integrin cytoplasmic domain-associated protein 1-alpha , integrin cytoplasmic domain-associated protein 1-beta

GENE ID SPECIES
298914 Rattus norvegicus
641420 Danio rerio
9270 Homo sapiens
16413 Mus musculus
513531 Bos taurus
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