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IFNGR2 (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Additionally we are shipping IFNGR2 Proteins (6) and IFNGR2 Kits (4) and many more products for this protein.
Showing 10 out of 119 products:
Human Polyclonal IFNGR2 Primary Antibody for WB - ABIN2782679
Jin, Kim, Kim, Baek, Kang, Yeo, Lee: Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53. in Biochemical and biophysical research communications 2008
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Human Polyclonal IFNGR2 Primary Antibody for IF (p), IHC (p) - ABIN749483
Kunis, Baruch, Rosenzweig, Kertser, Miller, Berkutzki, Schwartz: IFN-?-dependent activation of the brain's choroid plexus for CNS immune surveillance and repair. in Brain : a journal of neurology 2013
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Human Polyclonal IFNGR2 Primary Antibody for FACS, Neut - ABIN4899667
Lee, Liang, Huang, Jaing, Wang, Lin, Huang, Huang, Jou, Hsieh, Chia, Wu: Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease. in Journal of clinical immunology 2009
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Human Polyclonal IFNGR2 Primary Antibody for FACS - ABIN4896479
de Paus, Kilic, van Dissel, van de Vosse: Effect of amino acid substitutions in the human IFN-γR2 on IFN-γ responsiveness. in Genes and immunity 2011
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Human Polyclonal IFNGR2 Primary Antibody for IHC, IHC (p) - ABIN4321219
Ivanidze, Hoffmann, Lochmüller, Engel, Hohlfeld, Dornmair: Inclusion body myositis: laser microdissection reveals differential up-regulation of IFN-γ signaling cascade in attacked versus nonattacked myofibers. in The American journal of pathology 2011
Human Polyclonal IFNGR2 Primary Antibody for FACS - ABIN4896480
Tattermusch, Skinner, Chaussabel, Banchereau, Berry, McNab, OGarra, Taylor, Bangham: Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy. in PLoS pathogens 2012
Human Polyclonal IFNGR2 Primary Antibody for FACS, IHC (p) - ABIN652277
Kotenko, Izotova, Pollack, Mariano, Donnelly, Muthukumaran, Cook, Garotta, Silvennoinen, Ihle: Interaction between the components of the interferon gamma receptor complex. in The Journal of biological chemistry 1995
Mouse (Murine) Monoclonal IFNGR2 Primary Antibody for FACS, Neut - ABIN4900539
Krejci, Prochazkova, Bryja, Jelinkova, Pejchalova, Kozubik, Thompson, Wilcox: Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes. in Cellular signalling 2008
Myeloid cell IFNGR2 deficiency does not affect atherosclerosis development in LDLR (show LDLR Antibodies) knockout mice.
Data suggest IFNG (show IFNG Antibodies) plays various roles in dynamics of inflammation in subjects with underlying autoimmunity modeled as "canonical" and "non-canonical" pathways; in canonical pathway, IFNG (show IFNG Antibodies) dimerizes and binds to IFNGR1 (show IFNGR1 Antibodies) in IFNGR1 (show IFNGR1 Antibodies)/IFNGR2 hetero-multimer; STAT (show STAT1 Antibodies) transcription factors are involved in non-canonical pathway. (IFNG (show IFNG Antibodies) = interferon gamma (show IFNG Antibodies); IFNGR (show IFNGR1 Antibodies) = IFNG (show IFNG Antibodies) receptor; STAT (show STAT1 Antibodies) = signal transducers and activators of transcription)
IFN-gammaR2 T168N mutant diffusion is confined by distinct actin nanodomains where conformational changes required for JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) activation by IFN-gamma (show IFNG Antibodies) could not occur. Removing IFN-gammaR2 T168N-bound galectins restored lateral diffusion in lipid nanodomains and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies) signaling in patient cells, whereas adding galectins impaired these processes in control cells.
Statistical analyses revealed that four genetic variants in IFNGR1 (show IFNGR1 Antibodies) were marginally associated with the risk of Tuberculosis (P = 0.02-0.04), while other single nucleotide polymorphisms in IFNGR1 (show IFNGR1 Antibodies) and IFNGR2 did not exhibit any associations
The variability of potentially important functional polymorphic variants of the IFNG (show IFNG Antibodies), IFNGR2 and NEIL2 (show NEIL2 Antibodies) genes was characterized in representatives of four ethnic groups living in the Siberian region.
Fatal hemophagocytic lymphohistiocytosis has been described in two unrelated pediatric patients with underlying IFNGR2 deficiency.
The expression of IFNGR2 was significantly higher in patients with RA compared with control subjects and was significantly higher in patients in whom radiographic damage was more severe.
We report a molecular study of the two known patients with autosomal recessive, partial interferon-gamma (show IFNG Antibodies) receptor (IFN-gammaR (show IFNGR1 Antibodies))2 deficiency
IFN-gammaR2-deficient monocytes induce a higher percentage of IL-17 (show IL17A Antibodies)(+) cells from both healthy and IFN-gammaR2-deficient CD4 (show CD4 Antibodies)(+) T cells.
IFNGR2 haploinsufficiency may underlie clinical tuberculosis in children living in areas of endemic disease.
JAK2 (show JAK2 Antibodies) is a critical factor that stabilizes IFN-gammaR2 surface expression in Th17 cells from AMS (show MAT1A Antibodies) patients, making them sensitive to IFN-gamma (show IFNG Antibodies).
Four SNPs in IFNGR2, IL12RB1 (show IL12RB1 Antibodies), IL12RB2 (show IL12RB2 Antibodies), and IL23R (show IL23R Antibodies) were found to be associated with the MAP infection status of the resource population.
SNPs in IFNG (show IFNG Antibodies), IFNGR1 (show IFNGR1 Antibodies) and R2, IL22 (show IL22 Antibodies), and IL22RA1 (show IL22RA1 Antibodies) were analyzed for an association to Estimated breeding values for somatic cell score in Canadian Holstein bulls; no significant associations were found.
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
IFN-gamma receptor 2
, interferon gamma receptor 2
, interferon gamma receptor accessory factor 1
, interferon gamma receptor accessory factor-1
, interferon gamma receptor beta chain
, interferon gamma transducer 1