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Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. Additionally we are shipping IL17RA Antibodies (107) and IL17RA Proteins (31) and many more products for this protein.
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Identified the IL17RA rs4819554 SNP as a risk factor for psoriasis.
IL-17 receptor A and adenosine deaminase 2 (show CECR1 ELISA Kits) deficiency due to deletion mutations was found in siblings with chronic mucocutaneous candidiasis and chronic systemic inflammation.
In vitro, CSE stimulation significantly increased IL-17F and IL-17R in 16HBE (2.5%) and A549 (5%) while IL-17A and IL-17F in PBMC (10%). IL-17A and CSE stimulation, rather than CSE or rhIL-17A alone, increased proliferation in 16HBE and apoptosis in A549
The data indicate that the genetic variants of rs2275913 in IL-17A, rs763780 in IL-17F, and rs4819554 in IL-17RA may not play a role in the pathogenesis of preeclampsia in Chinese Han women.
IL17F (show IL17F ELISA Kits) and IL17RA polymorphisms modulate susceptibility to cerebral malaria(CM) and provide evidence that IL-17F (show IL17F ELISA Kits) protects against CM.
Increased expression of IL-17RA plays an important role in gastric cancer progression, migration and prognosis.
Both genetic variants of IL-17R (rs882643 and rs2241049) were associated with PGD (show PGD ELISA Kits). This confirms a genetic predisposition toward PGD (show PGD ELISA Kits) and suggests a role of IL-17 (show IL17A ELISA Kits) in driving neutrophilia in PGD (show PGD ELISA Kits).
The presence of IL7R (show IL7R ELISA Kits) polymorphisms seems to be related to severe liver disease in HIV/hepatitis c virus coinfected patients.
expression of immunoreactivity for IL-17A (show IL17A ELISA Kits), IL-17RA, IL-17E (show IL25 ELISA Kits), and IL-17F (show IL17F ELISA Kits) was significantly elevated in prostatic tissue from benign prostatic hyperplasia and prostate cancer compared with that in controls
IL17RA polymorphisms, but not those of IL17 (show IL17A ELISA Kits), can influence both the development and the bilaterality of papillary thyroid carcinoma
IL-17RA in non hematopoietic cells regulates recruitment of neutrophils to the lung during the adaptive phase of the immune response.
Bronchial epithelial TLR2 (show TLR2 ELISA Kits)/IL17R signaling crosstalk is necessary for lung IL17 (show IL17A ELISA Kits) homeostasis and is compromised by morphine.
IL-17 (show IL17A ELISA Kits) signaling through IL-17RA is an important driver of lung inflammation and airway hyperresponsiveness.
results suggest that the p38alpha (show MAPK14 ELISA Kits)-MKP-1 (show DUSP1 ELISA Kits) signaling axis links IL-17R signaling in tissue-resident cells to autoimmune inflammation dependent on infiltrating T(H)17 cells.
There were no significant differences in clinical scores and numbers of infiltrating eosinophils among IL-25KO, TSLPR (show CRLF2 ELISA Kits) KO, and wild-type mice.
IL-17RA signaling is critical for the development of renal pathology in autoimmune glomerulonephritis.IL-17 enhanced the production of proinflammatory cytokines and chemokines from tubular epithelial cells.
Il17ra appears to be a novel modulator of monocyte phenotype and possible therapeutic target in renal fibrosis
IL-17 (show IL17A ELISA Kits) expression is higher in C57BL/6 versus BALB/c cornea after infection and that the latter group has more MerTK (show MERTK ELISA Kits)+ cells.
It was concluded that TLR signaling can directly stimulate the expression of IL-17RA, but not IL-17RC (show IL17RC ELISA Kits), in neuroglial cells, which functionally respond to IL-17A (show IL17A ELISA Kits) by secreting chemokines, and accelerating CD4 (show CD4 ELISA Kits) cell migration.
Absence of IL-17RA leads to a Th2-like phenotype characterized by IL-4 (show IL4 ELISA Kits) production and suggests that IL-17RA signaling plays a critical role in the regulation of IL-4 (show IL4 ELISA Kits) in collagen-induced arthritis and development of autoimmune inflammation of the joint.
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor\; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.
IL-17 receptor A
, interleukin-17 receptor A