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IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. Additionally we are shipping Interleukin 31 Kits (54) and Interleukin 31 Proteins (42) and many more products for this protein.
Showing 10 out of 112 products:
Mouse (Murine) Monoclonal IL31 Primary Antibody for BCA - ABIN2665157
McCandless, Rugg, Fici, Messamore, Aleo, Gonzales: Allergen-induced production of IL-31 by canine Th2 cells and identification of immune, skin, and neuronal target cells. in Veterinary immunology and immunopathology 2013
Show all 6 references for ABIN2665157
Human Monoclonal IL31 Primary Antibody for BCA - ABIN2665158
Arai, Tsuji, Takeda, Akiyama, Saito: A single dose of interleukin-31 (IL-31) causes continuous itch-associated scratching behaviour in mice. in Experimental dermatology 2013
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Mouse (Murine) Polyclonal IL31 Primary Antibody for EIA, IHC (p) - ABIN500004
Diveu, Lak-Hal, Froger, Ravon, Grimaud, Barbier, Hermann, Gascan, Chevalier: Predominant expression of the long isoform of GP130-like (GPL) receptor is required for interleukin-31 signaling. in European cytokine network 2005
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Human Polyclonal IL31 Primary Antibody for EIA, WB - ABIN500006
Bilsborough, Leung, Maurer, Howell, Boguniewicz, Boguniewcz, Yao, Storey, LeCiel, Harder, Gross: IL-31 is associated with cutaneous lymphocyte antigen-positive skin homing T cells in patients with atopic dermatitis. in The Journal of allergy and clinical immunology 2006
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Human Polyclonal IL31 Primary Antibody for IHC (p), WB - ABIN303271
Dillon, Sprecher, Hammond, Bilsborough, Rosenfeld-Franklin, Presnell, Haugen, Maurer, Harder, Johnston, Bort, Mudri, Kuijper, Bukowski, Shea, Dong, Dasovich, Grant, Lockwood, Levin, LeCiel, Waggie et al.: Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. ... in Nature immunology 2004
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Human Polyclonal IL31 Primary Antibody for EIA, FACS - ABIN952927
Le Saux, Rousseau, Barbier, Ravon, Grimaud, Danger, Froger, Chevalier, Gascan: Molecular dissection of human interleukin-31-mediated signal transduction through site-directed mutagenesis. in The Journal of biological chemistry 2010
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IL-31 affects keratinocyte differentiation in multiple ways and the IL-1 (show IL1A Antibodies) cytokine network is a major downstream effector of IL-31 signaling in deregulating the physical skin barrier.
Oncostatin M (show OSM Antibodies) and interleukin-31: Cytokines, receptors, signal transduction and physiology.
The results of our analyses regarding serum levels and receptor expression do not suggest a central role of IL-31 in Mycosis fungoides/Sezary syndrome pathogenesis.
In summary, TGF-beta1 (show TGFB1 Antibodies) and IL-31 were linked to progression from chronic hepatitis B to liver cirrhosis, and correlated well with the severity of disease.
An increase of IL-31 serum levels in postmenopausal women with decreased bone mineral density, is shown.
a possible systemic involvement of IL-31 and the absence of a systemic involvement of IL-33 (show IL33 Antibodies) in allergic contact dermatitis.
crucial requirements for IL-31 signaling and its counter-regulation by SOCS3 (show SOCS3 Antibodies)
IL-31 expression in allergic rhinitis aggravated and amplified Th2 inflammation as well as mucin (show SLC13A2 Antibodies) production
The IL-31 serum level was significantly higher in cutaneous T-cell lymphoma patients than in the control group but there were no positive correlation between IL-31 serum level and pruritus.
IL-31 is overexpressed in the lesional skin of LP but its expression does not correlate with intensity of pruritus.
IL-31 upregulates IL-31RA (show IL31RA Antibodies) expression in DRG neuron cell bodies, and cutaneous-injected IL-31-induced itching is enhanced by DRG IL-31RA (show IL31RA Antibodies) expression in mice
our results suggest a functional cooperation between NFAT1 (show NFAT1 Antibodies) and JunB (show JUNB Antibodies) in mediating IL-31 gene expression in CD4 (show CD4 Antibodies)(+) T cells
Data not only illustrate various functions that cysteines perform during IL-31 biosynthesis and secretion, but also highlight their potential roles in cytokine effector functions.
IL-31 may be involved in promoting the dermatitis and epithelial responses that characterize allergic and non-allergic diseases
IL-31 interaction with IL-31 receptor (IL-31R) is identified in an acute model of T helper cell type 2 inflammation in the lung.
these data provide the first evidence of a function for IL-31-IL-31R interactions in limiting the magnitude of type 2 inflammatory responses within the intestine.
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004