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Internexin Neuronal Intermediate Filament Protein, alpha Proteins (INA)

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Additionally we are shipping Internexin Neuronal Intermediate Filament Protein, alpha Antibodies (116) and Internexin Neuronal Intermediate Filament Protein, alpha Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
INA 9118 Q16352
INA 226180 P46660
INA 24503 P23565
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Top Internexin Neuronal Intermediate Filament Protein, alpha Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,433.83
Details

INA Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Internexin Neuronal Intermediate Filament Protein, alpha (INA) Interaction Partners

Human Internexin Neuronal Intermediate Filament Protein, alpha (INA) interaction partners

  1. Gonadotropinomas, null cell pituitary adenomas, and thyrotropinomas exhibit high levels of intracellular INA protein indicating neuronal transdifferentiation.

  2. alpha-Internexin was expressed in 53% of 350 pancreatic neuroendocrine tumors. Reduced expression of alpha-internexin was significantly associated with advanced stage metastases, recurrence and shorter overall survival.

  3. High INA expression is associated with grade II gliomas.

  4. INA may provide additional biologic information relevant to delineation of both pancreatic neuroendocrine neoplasms (NEN) tumor phenotypes and clinical behavior.

  5. the importance of alpha-internexin and NF-L (show NEFL Proteins) in regulating the conformations of NF-M (show NEFM Proteins) and NF-H (show NEFH Proteins)

  6. alpha-internexin expression in neuroblastoma (show ARHGEF16 Proteins)

  7. The discovery of alpha-internexin in the cytoplasmic inclusions implicates novel mechanisms of pathogenesis in inclusion diseeae and other neurological diseases with pathological accumulations of IFs.

  8. Abnormal neuronal intermediate filament inclusions of alpha-internexin have been identified as the pathological hallmark of neuronal intermediate filament inclusion disease

  9. Expression of the 2 markers, alpha-internexin and peripherin (show PRPH Proteins), in a small round cell tumor strongly favors the diagnosis of neuroblastoma (show ARHGEF16 Proteins).

  10. Alpha-Internexin (INA) expression appears to be a simple, reliable prognostic marker and a surrogate marker of 1p19q codeletion.

Mouse (Murine) Internexin Neuronal Intermediate Filament Protein, alpha (INA) interaction partners

  1. Neurofilament light chain (NFL (show NEFL Proteins)) and neuronal intermediate filament protein (show GFAP Proteins) alpha-internexin accumulate in axon swellings in the spinal white matter in superoxide dismutase (SOD)-1 (show SOD1 Proteins) mouse.

  2. Therefore, the cre transgene driven by mouse alpha-internexin promoter, described here, provides a useful animal model to specifically manipulate genes in the developing nervous system.

  3. Alpha-internexin coassembles with all 3 neurofilament proteins into a single network of filaments. All of them are functionally interdependent. It is a fourth subunit of neurofilaments in the adult CNS.

  4. abnormal accumulation of neuronal IFs in the swelling axons and abnormal translocation of alpha-internexin in the nuclei of the spinal motor neurons from dystonia musculorum mice may not directly cause cell death of the spinal motor neurons

  5. RE1 silencing transcription factor (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin, NF-H (show NEFH Proteins) and NF-M (show CEBPB Proteins) genes

Internexin Neuronal Intermediate Filament Protein, alpha (INA) Protein Profile

Protein Summary

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.

Gene names and symbols associated with INA

  • zgc:65851 (zgc:65851)
  • internexin neuronal intermediate filament protein, alpha (ina-A)
  • internexin neuronal intermediate filament protein, alpha (ina-b)
  • internexin neuronal intermediate filament protein, alpha (ina-a)
  • low molecular weight neuronal intermediate filament (nif)
  • internexin neuronal intermediate filament protein, alpha (INA)
  • internexin neuronal intermediate filament protein, alpha a (inaa)
  • internexin neuronal intermediate filament protein, alpha (ina)
  • internexin neuronal intermediate filament protein, alpha (Ina)
  • AV028420 protein
  • cb126 protein
  • CTDSPL protein
  • INA protein
  • ina-a protein
  • ina-b protein
  • Inexa protein
  • Intlaa protein
  • MGC53005 protein
  • MGC69277 protein
  • MGC82496 protein
  • NEF5 protein
  • NF-66 protein
  • Nf66 protein
  • sb:cb126 protein
  • si:ch211-67n3.6 protein
  • TXBP-1 protein
  • xefiltin protein
  • xina protein
  • XNIF protein

Protein level used designations for INA

internexin neuronal intermediate filament protein, alpha , intermediate filament protein , low molecular weight neuronal intermediate filament , 66 kDa neurofilament protein , alpha-Inx , alpha-internexin , neurofilament 5 (66kD) , neurofilament-66, tax-binding protein , neurofilament-66 , internexin, alpha

GENE ID SPECIES
321113 Danio rerio
378565 Xenopus laevis
379168 Xenopus laevis
446639 Xenopus laevis
448000 Xenopus (Silurana) tropicalis
450709 Pan troglodytes
555251 Danio rerio
100101732 Xenopus (Silurana) tropicalis
100599632 Nomascus leucogenys
9118 Homo sapiens
226180 Mus musculus
24503 Rattus norvegicus
532236 Bos taurus
486869 Canis lupus familiaris
100153400 Sus scrofa
101085925 Felis catus
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